CEMdb

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HGNC approved symbol	Pfam domains	Uniprot ID(mouse)	HGNC approved name	Uniprot ID(human)	Function	Modification	Protein complex	Target entity	Product
HGNC approved symbol	Pfam domains	UniProt ID (mouse)	HGNC approved name	UniProt ID (human)	Function	Modification	Protein complex	Target entity	Product
#	LEDGF PF11467 472-578 PWWP PF00855 5-87 Pfam-B_32406 PB032406 111-159	HDGR2_MOUSE	#	HDGR2_HUMAN	Histone modification read	#	#	H3K79me3 H4K20me3 H3K36me3	#
A1CF	DND1_DSRM PF14709 445-523 RRM_1 PF00076 58-127 138-203 RRM_6 PF14259 233-297	A1CF_MOUSE	APOBEC1 complementation factor	A1CF_HUMAN	RNA modification	RNA deamination	APOB_mRNA_editosome	mRNA mC	U
ACTB	Actin PF00022 2-375	ACTB_MOUSE	actin beta	ACTB_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1 NuA4 NuA4-related complex	#	#
ACTL6A	Actin PF00022 8-429	ACL6A_MOUSE	actin-like 6A	ACL6A_HUMAN	Chromatin remodelling cofactor	#	BAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB SWI/SNF BRM-BRG1 Ino80 NuA4 NuA4-related complex SRCAP	#	#
ACTL6B	Actin PF00022 8-426	ACL6B_MOUSE	actin-like 6B	ACL6B_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF BRM-BRG1	#	#
ACTR3B	Actin PF00022 3-412	ARP3B_MOUSE	ARP3 actin-related protein 3 homolog B (yeast)	ARP3B_HUMAN	Chromatin remodelling	#	#	H2A H3 H4	#
ACTR5	Actin PF00022 30-570	ARP5_MOUSE	ARP5 actin-related protein 5 homolog (yeast)	ARP5_HUMAN	Chromatin remodelling	#	Ino80	#	#
ACTR6	Actin PF00022 1-395	ARP6_MOUSE	ARP6 actin-related protein 6 homolog (yeast)	ARP6_HUMAN	Chromatin remodelling cofactor	#	SRCAP	#	#
ACTR8	Actin PF00022 43-621	ARP8_MOUSE	ARP8 actin-related protein 8 homolog (yeast)	ARP8_HUMAN	Histone modification read	#	Ino80	#	#
ADNP	Homeobox PF00046 765-813 Pfam-B_10803 PB010803 691-762 Pfam-B_21724 PB021724 921-1100 Pfam-B_29916 PB029916 615-646	ADNP_MOUSE	activity-dependent neuroprotector homeobox	ADNP_HUMAN	Chromatin remodelling cofactor	#	#	#	#
AEBP2	Pfam-B_22101 PB022101 1-79 Pfam-B_8048 PB008048 401-515 zf-H2C2_2 PF13465 315-341	AEBP2_MOUSE	AE binding protein 2	AEBP2_HUMAN	Histone modification write cofactor	Histone methylation	PRC2	#	#
AICDA	APOBEC_N PF08210 11-181	AICDA_MOUSE	activation-induced cytidine deaminase	AICDA_HUMAN	DNA modification	DNA demethylation	APOB_mRNA_editosome	ssDNA hmC	hmU
AIRE	PHD PF00628 298-343 Pfam-B_9104 PB009104 481-543 SAND PF01342 189-249 Sp100 PF03172 1-106	AIRE_MOUSE	autoimmune regulator	AIRE_HUMAN	Histone modification read TF	# #	#	H3K4 H3K4me3 DNA motif	#
ALKBH1	2OG-FeII_Oxy_2 PF13532 98-344	ALKB1_MOUSE	alkB alkylation repair homolog 1 (E. coli)	ALKB1_HUMAN	Histone modification	#	#	H2A	#
ANKRD32	Ank_2 PF12796 783-871 845-931 Pfam-B_101142 PB101142 932-1056 Pfam-B_12624 PB012624 231-430 Pfam-B_18156 PB018156 1-229 Pfam-B_81366 PB081366 641-782	ANR32_MOUSE	ankyrin repeat domain 32	ANR32_HUMAN	Histone modification read	#	#	H2AXS139	#
ANP32A	LRR_9 PF14580 17-166	AN32A_MOUSE	acidic (leucine-rich) nuclear phosphoprotein 32 family member A	AN32A_HUMAN	Chromatin remodelling cofactor	#	#	#	#
ANP32B	LRR_4 PF12799 88-136 Pfam-B_30686 PB030686 171-249	AN32B_MOUSE	acidic (leucine-rich) nuclear phosphoprotein 32 family member B	AN32B_HUMAN	Histone chaperone	#	#	H3 H4	#
ANP32E	LRR_4 PF12799 88-133 LRR_8 PF13855 65-125 Pfam-B_38005 PB038005 215-262 Pfam-B_94319 PB094319 171-200	AN32E_MOUSE	acidic (leucine-rich) nuclear phosphoprotein 32 family member E	AN32E_HUMAN	Histone chaperone Histone modification read	# #	SWR	H2A.Z	#
APBB1	PID PF00640 370-509 543-664 Pfam-B_23321 PB023321 1-215 WW PF00397 255-283	APBB1_MOUSE	amyloid beta (A4) precursor protein-binding family B member 1 (Fe65)	APBB1_HUMAN	Histone modification	#	#	H2AX	#
APEX1	Exo_endo_phos PF03372 65-309 Pfam-B_21616 PB021616 1-39	APEX1_MOUSE	APEX nuclease (multifunctional DNA repair enzyme) 1	APEX1_HUMAN	DNA modification cofactor	DNA demethylation	#	#	#
APOBEC1	APOBEC_N PF08210 17-186	ABEC1_MOUSE	apolipoprotein B mRNA editing enzyme catalytic polypeptide 1	ABEC1_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	APOB_mRNA_editosome	ssDNA mRNA mC	U
APOBEC2	APOBEC_C PF05240 159-216 Pfam-B_38491 PB038491 1-39	ABEC2_MOUSE	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 2	ABEC2_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	#	ssDNA mRNA mC	hmU
APOBEC3A	APOBEC_C PF05240 133-187	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3A	ABC3A_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	#	ssDNA mRNA mC	dhU
APOBEC3B	APOBEC_C PF05240 316-370 APOBEC_N PF08210 11-190	ABEC3_MOUSE	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B	ABC3B_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	#	ssDNA mRNA mC	dhU
APOBEC3C	APOBEC_C PF05240 128-182	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3C	ABC3C_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	#	ssDNA mRNA mC	dhU
APOBEC3D	APOBEC_C PF05240 140-194 324-378	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3D	ABC3D_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	#	ssDNA mRNA mC	dhU
APOBEC3F	APOBEC_N PF08210 3-189 199-373	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3F	ABC3F_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	APOB_mRNA_editosome	ssDNA mRNA mC	dhU
APOBEC3G	APOBEC_N PF08210 3-182 202-380	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G	ABC3G_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	APOB_mRNA_editosome	ssDNA mRNA mC	dhU
APOBEC3H	APOBEC_C PF05240 116-174 dCMP_cyt_deam_1 PF00383 24-99	#	apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3H	ABC3H_HUMAN	DNA modification RNA modification	DNA demethylation mRNA editing	APOB_mRNA_editosome	ssDNA mRNA mC	dhU
ARID1A	ARID PF01388 1015-1104 DUF3518 PF12031 1975-2231 Pfam-B_16906 PB016906 451-499 Pfam-B_1854 PB001854 281-379	ARI1A_MOUSE	AT rich interactive domain 1A (SWI-like)	ARI1A_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm WINAC bBAF SWI/SNF BRM-BRG1	DNA motif	#
ARID1B	ARID PF01388 1050-1140 DUF3518 PF12031 1926-2182 Pfam-B_60945 PB060945 291-369 Pfam-B_7257 PB007257 371-449	#	AT rich interactive domain 1B (SWI1-like)	ARI1B_HUMAN	Histone modification write	Histone ubiquitination	BAF nBAF npBAF PBAF SWI/SNF-like_EPAFa SWI/SNF-like EPAFB SWI/SNF BRM-BRG1	H2BK120 DNA motif	#
ARID2	ARID PF01388 10-101 Pfam-B_11884 PB011884 1660-1747 Pfam-B_14804 PB014804 1051-1098 Pfam-B_649 PB000649 1529-1658 Pfam-B_6603 PB006603 1239-1268 RFX_DNA_binding PF02257 517-604	#	AT rich interactive domain 2 (ARID RFX-like)	ARID2_HUMAN	Chromatin remodelling cofactor	#	PBAF	DNA motif	#
ARID4A	ARID PF01388 306-397 Pfam-B_1988 PB001988 1071-1111 1166-1240 RBB1NT PF08169 168-263 Tudor-knot PF11717 573-630	#	AT rich interactive domain 4A (RBP1-like)	ARI4A_HUMAN	Histone modification write cofactor	Histone acetylation	mSin3A	DNA motif	#
ARID4B	ARID PF01388 304-394 Pfam-B_15110 PB015110 771-828 RBB1NT PF08169 166-264 Tudor-knot PF11717 569-626	ARI4B_MOUSE	AT rich interactive domain 4B (RBP1-like)	ARI4B_HUMAN	Histone modification write cofactor	Histone acetylation	mSin3A	DNA motif	#
ARNTL	HLH PF00010 73-126 PAS PF00989 146-253 PAS_11 PF14598 337-444 Pfam-B_2781 PB002781 455-619	BMAL1_MOUSE	aryl hydrocarbon receptor nuclear translocator-like	BMAL1_HUMAN	Histone modification write cofactor TF	# TF activator	#	#	#
ARRB1	Arrestin_C PF02752 193-356 Arrestin_N PF00339 18-174	ARRB1_MOUSE	arrestin beta 1	ARRB1_HUMAN	Histone modification	#	#	#	#
ASF1A	ASF1_hist_chap PF04729 1-154	ASF1A_MOUSE	anti-silencing function 1A histone chaperone	ASF1A_HUMAN	Histone chaperone	#	#	H3 H4	#
ASF1B	ASF1_hist_chap PF04729 1-154	ASF1B_MOUSE	anti-silencing function 1B histone chaperone	ASF1B_HUMAN	Histone chaperone	#	#	H3 H4	#
ASH1L	BAH PF01426 2661-2798 Bromodomain PF00439 2453-2538 PHD PF00628 2587-2631 Pfam-B_14208 PB014208 1818-1847 Pfam-B_18246 PB018246 2310-2419 Pfam-B_25586 PB025586 1473-1507 Pfam-B_4663 PB004663 1023-1054 1180-1377 Pfam-B_6310 PB006310 1509-1554 SET PF00856 2156-2261	ASH1L_MOUSE	ash1 (absent small or homeotic)-like (Drosophila)	ASH1L_HUMAN	Histone modification write	Histone methylation	#	H3K36	H3K36me
ASH2L	Pfam-B_11232 PB011232 499-622 Pfam-B_12412 PB012412 361-417 SPRY PF00622 418-497	ASH2L_MOUSE	ash2 (absent small or homeotic)-like (Drosophila)	ASH2L_HUMAN	Histone modification write cofactor	Histone methylation	COMPASS Menin-associated_HMT MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7 COMPASS-like MLL3 4	#	#
ASXL1	ASXH PF13919 231-362 HARE-HTH PF05066 11-83 PHD_3 PF13922 1475-1539 Pfam-B_4087 PB004087 970-1084	ASXL1_MOUSE	additional sex combs like transcriptional regulator 1	ASXL1_HUMAN	Histone modification erase Polycomb group (PcG) protein	Histone deubiquitination #	PR-DUB	H2AK119	H2AK119ub1
ASXL2	ASXH PF13919 249-381 HARE-HTH PF05066 11-83 PHD_3 PF13922 1370-1433 Pfam-B_4087 PB004087 944-1090	ASXL2_MOUSE	additional sex combs like transcriptional regulator 2	ASXL2_HUMAN	Histone modification read	#	#	H3K4 H3K9	#
ASXL3	ASXH PF13919 229-361 HARE-HTH PF05066 10-81 PHD_3 PF13922 2183-2246 Pfam-B_17129 PB017129 941-1279 Pfam-B_20113 PB020113 751-939 Pfam-B_27498 PB027498 1341-1411 Pfam-B_34336 PB034336 1281-1339 Pfam-B_6874 PB006874 601-669	ASXL3_MOUSE	additional sex combs like transcriptional regulator 3	ASXL3_HUMAN	Scaffold protein Polycomb group (PcG) protein	# #	#	#	#
ATAD2	AAA PF00004 463-598 Bromodomain PF00439 993-1075 Pfam-B_11064 PB011064 870-958 Pfam-B_23116 PB023116 1-56 Pfam-B_40477 PB040477 57-79	ATAD2_MOUSE	ATPase family AAA domain containing 2	ATAD2_HUMAN	Chromatin remodelling	#	#	#	#
ATAD2B	AAA PF00004 437-572 Bromodomain PF00439 967-1050 Pfam-B_11064 PB011064 896-932 Pfam-B_130965 PB130965 330-388	#	ATPase family AAA domain containing 2B	ATD2B_HUMAN	Histone modification read	#	#	H1.4 H2A H2B H3 and H4	#
ATF2	bZIP_1 PF00170 349-413	ATF2_MOUSE	activating transcription factor 2	ATF2_HUMAN	Histone modification write TF	Histone acetylation TF activator	#	H2B H4 DNA motif	#
ATF7IP	Pfam-B_2570 PB002570 450-518	MCAF1_MOUSE	activating transcription factor 7 interacting protein	MCAF1_HUMAN	Histone modification write cofactor	Histone methylation	#	#	#
ATM	FAT PF02259 2096-2489 FATC PF02260 3024-3056 PI3_PI4_kinase PF00454 2711-2962 Pfam-B_10220 PB010220 1575-1713 Pfam-B_13450 PB013450 602-830 Pfam-B_16049 PB016049 1715-1818 Pfam-B_17604 PB017604 1819-1953 Pfam-B_3386 PB003386 861-1458 TAN PF11640 5-166	ATM_MOUSE	ATM serine/threonine kinase	ATM_HUMAN	Histone modification write	Histone phosphorylation	#	H2AXS139	#
ATN1	Atrophin-1 PF03154 1-163 349-1190	ATN1_MOUSE	atrophin 1	ATN1_HUMAN	Histone modification erase cofactor	#	#	#	#
ATR	FAT PF02259 1771-2092 FATC PF02260 2612-2644 PI3_PI4_kinase PF00454 2321-2567 Pfam-B_15857 PB015857 1226-1489 Pfam-B_17853 PB017853 1-129 Pfam-B_20071 PB020071 291-659 Pfam-B_21066 PB021066 131-289 Pfam-B_21726 PB021726 661-1009 Pfam-B_22672 PB022672 1011-1079 UME PF08064 1119-1225	ATR_MOUSE	ATR serine/threonine kinase	ATR_HUMAN	Histone modification write	Histone phosphorylation	#	H2AX	#
ATRX	Helicase_C PF00271 2076-2155 Pfam-B_12326 PB012326 1906-2016 Pfam-B_14952 PB014952 1242-1362 Pfam-B_16104 PB016104 2368-2490 Pfam-B_16400 PB016400 1424-1474 Pfam-B_17163 PB017163 1364-1422 Pfam-B_19720 PB019720 751-889 Pfam-B_24253 PB024253 1181-1239 Pfam-B_3534 PB003534 45-304 SNF2_N PF00176 1563-1889	ATRX_MOUSE	alpha thalassemia/mental retardation syndrome X-linked	ATRX_HUMAN	Chromatin remodelling	#	#	H3K9me2 H3K9me3 H3K4	#
ATXN7	Pfam-B_15485 PB015485 781-879 Pfam-B_23658 PB023658 129-174 Pfam-B_6735 PB006735 491-579 SCA7 PF08313 318-397	ATX7_MOUSE	ataxin 7	ATX7_HUMAN	Histone modification write cofactor	Histone acetylation	SAGA	#	#
ATXN7L3	Pfam-B_25595 PB025595 276-345 SCA7 PF08313 201-239 Sgf11 PF08209 80-112	AT7L3_MOUSE	ataxin 7-like 3	AT7L3_HUMAN	Histone modification erase cofactor	Histone deubiquitination	SAGA	#	#
AURKA	Pfam-B_20489 PB020489 1-59 Pkinase PF00069 133-383	AURKA_MOUSE	aurora kinase A	AURKA_HUMAN	Histone modification write	Histone phosphorylation	#	H3	H3S10ph
AURKB	Pfam-B_34716 PB034716 1-46 Pkinase PF00069 77-327	AURKB_MOUSE	aurora kinase B	AURKB_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10 H3S28	#
AURKC	Pkinase PF00069 43-293	AURKC_MOUSE	aurora kinase C	AURKC_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10 H3S28	#
BABAM1	Pfam-B_4074 PB004074 1-327	BABA1_MOUSE	BRISC and BRCA1 A complex member 1	BABA1_HUMAN	Histone modification erase cofactor	Histone deubiquitination	BRISC BRCA1-A	#	#
BAHD1	BAH PF01426 623-779	BAHD1_MOUSE	bromo adjacent homology domain containing 1	BAHD1_HUMAN	Chromatin remodelling	#	#	H3K27me3	#
BANP	BEN PF10523 249-322	BANP_MOUSE	BTG3 associated nuclear protein	BANP_HUMAN	Histone modification write	Histone acetylation	#	H3K9 H4K8	#
BAP1	Peptidase_C12 PF01088 4-217 Pfam-B_14567 PB014567 441-579 Pfam-B_16218 PB016218 271-439 Pfam-B_4660 PB004660 581-693	BAP1_MOUSE	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	BAP1_HUMAN	Histone modification erase Polycomb group (PcG) protein	Histone deubiquitination #	PR-DUB	H2AK119ub1	H2AK119
BARD1	Ank PF00023 427-459 460-491 493-525 BRCT PF00533 568-640 Pfam-B_30184 PB030184 161-239 Pfam-B_32178 PB032178 241-290 Pfam-B_32432 PB032432 291-339 Pfam-B_33025 PB033025 723-775 zf-RING_6 PF14835 41-105	BARD1_MOUSE	BRCA1 associated RING domain 1	BARD1_HUMAN	Histone modification write	Histone ubiquitination	BRCC BRCA1-A	H2AX H2A H2B H3 H4	H2AXub H2Aub H2Bub H3ub H4ub
BAZ1A	Bromodomain PF00439 1438-1521 DDT PF02791 422-487 PHD PF00628 1150-1198 Pfam-B_18021 PB018021 670-767 Pfam-B_18567 PB018567 769-877 Pfam-B_19398 PB019398 1210-1430 WAC_Acf1_DNA_bd PF10537 22-122 WHIM1 PF15612 592-640	BAZ1A_MOUSE	bromodomain adjacent to zinc finger domain 1A	BAZ1A_HUMAN	Histone chaperone	#	ACF CHRAC	#	#
BAZ1B	Bromodomain PF00439 1348-1431 PHD PF00628 1186-1234 WAC_Acf1_DNA_bd PF10537 20-120 WHIM1 PF15612 724-773 WHIM2 PF15613 899-936 WHIM3 PF15614 991-1031	BAZ1B_MOUSE	bromodomain adjacent to zinc finger domain 1B	BAZ1B_HUMAN	Histone modification write	Histone phosphorylation	B-WICH WINAC	H2AXT142 H3	H2AXY142ph
BAZ2A	Bromodomain PF00439 1802-1885 DDT PF02791 848-910 MBD PF01429 546-620 PHD PF00628 1678-1726 Pfam-B_14139 PB014139 1518-1541 Pfam-B_1702 PB001702 2-228 Pfam-B_25722 PB025722 1211-1279 Pfam-B_3124 PB003124 701-789 1085-1136 Pfam-B_32186 PB032186 1484-1516 Pfam-B_6766 PB006766 331-489 WHIM1 PF15612 950-999 WHIM3 PF15614 1439-1480	BAZ2A_MOUSE	bromodomain adjacent to zinc finger domain 2A	BAZ2A_HUMAN	Chromatin remodelling Histone modification erase	# Histone deacetylation	NoRC	H4K16ac DNA motif	H4K5 H4K8 H4K12
BAZ2B	Bromodomain PF00439 2069-2151 DDT PF02791 1087-1149 MBD PF01429 739-813 PHD PF00628 1933-1981 Pfam-B_10350 PB010350 521-649 Pfam-B_12038 PB012038 1200-1479 Pfam-B_13066 PB013066 91-399 Pfam-B_1587 PB001587 401-519 Pfam-B_17078 PB017078 1618-1728 Pfam-B_17427 PB017427 1-89 Pfam-B_9375 PB009375 1481-1616	#	bromodomain adjacent to zinc finger domain 2B	BAZ2B_HUMAN	Histone modification read	#	#	H1.4ac H2Aac H2Bac H3ac H4Kac	#
BCOR	Ank_2 PF12796 1460-1560 Pfam-B_11277 PB011277 41-289 Pfam-B_26758 PB026758 300-329 Pfam-B_27995 PB027995 1241-1359 Pfam-B_30654 PB030654 1361-1419 Pfam-B_5207 PB005207 421-1239	BCOR_MOUSE	BCL6 corepressor	BCOR_HUMAN	Polycomb group (PcG) protein	#	BCOR	#	#
BCORL1	Ank_2 PF12796 1410-1486 1426-1519 Pfam-B_1109 PB001109 110-149 Pfam-B_16739 PB016739 560-637 Pfam-B_20248 PB020248 740-800 Pfam-B_31169 PB031169 1-76 Pfam-B_8912 PB008912 383-533	BCORL_MOUSE	BCL6 corepressor-like 1	BCORL_HUMAN	Histone modification erase cofactor	Histone deacetylation	BCOR	H3K36me2	#
BMI1	zf-C3HC4 PF00097 18-56	BMI1_MOUSE	BMI1 proto-oncogene polycomb ring finger	BMI1_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
BPTF	Bromodomain PF00439 2936-3019 DDT PF02791 240-300 PHD PF00628 392-437 2869-2918 Pfam-B_14861 PB014861 2113-2229 Pfam-B_26081 PB026081 91-205 Pfam-B_911 PB000911 1922-2111 Pfam-B_94218 PB094218 1-89 WHIM1 PF15612 339-388	#	bromodomain PHD finger transcription factor	BPTF_HUMAN	Chromatin remodelling	#	NuRF	#	#
BRCA1	BRCT PF00533 1648-1723 1756-1842 BRCT_assoc PF12820 344-508 EIN3 PF04873 648-978 Pfam-B_17893 PB017893 1404-1493 zf-C3HC4 PF00097 24-64	BRCA1_MOUSE	breast cancer 1 early onset	BRCA1_HUMAN	Histone modification write cofactor Histone modification write cofactor Histone modification write cofactor TF TF	Histone acetylation Histone methylation Histone ubiquitination TF activator TF repressor	BRCC BRCA1-A	DNA motif	#
BRCA2	BRCA-2_OB1 PF09103 2670-2800 BRCA-2_OB3 PF09104 3052-3190 BRCA-2_helical PF09169 2479-2667 BRCA2 PF00634 1002-1036 1212-1246 1421-1455 1517-1551 1664-1698 1837-1871 1971-2005 2051-2085 Pfam-B_13057 PB013057 2141-2448 Pfam-B_47717 PB047717 2449-2478 Pfam-B_8258 PB008258 651-989 Tower PF09121 2831-2872	BRCA2_MOUSE	breast cancer 2 early onset	BRCA2_HUMAN	Histone modification write	Histone acetylation	BRCC	H3 H4 ssDNA	#
BRCC3	JAB PF01398 7-148	BRCC3_MOUSE	BRCA1/BRCA2-containing complex subunit 3	BRCC3_HUMAN	Histone modification erase	Histone deubiquitination	BRISC BRCA1-A	H2AK63 H2AXK63	H2A H2AX
BRD1	Bromodomain PF00439 571-654 EPL1 PF10513 46-196 PHD_2 PF13831 228-262 PWWP PF00855 927-1042 zf-HC5HC2H_2 PF13832 269-388	#	bromodomain containing 1	BRD1_HUMAN	Histone modification read	#	MOZ/MORF	H3K36me3 H3	#
BRD2	Bromodomain PF00439 84-168 353-441 Pfam-B_12618 PB012618 624-776 Pfam-B_14336 PB014336 541-613	BRD2_MOUSE	bromodomain containing 2	BRD2_HUMAN	Histone modification read	#	#	H3K9me2 H3K14me2 H4K5ac H4K12ac	#
BRD3	Bromodomain PF00439 42-128 315-403	BRD3_MOUSE	bromodomain containing 3	BRD3_HUMAN	Histone modification read	#	#	H3K9me2 H3K14me2 H4K5ac H4K12ac	#
BRD4	Bromodomain PF00439 67-152 357-445 Pfam-B_14896 PB014896 1187-1263 Pfam-B_15118 PB015118 509-647 Pfam-B_18611 PB018611 648-667 Pfam-B_24632 PB024632 833-892 Pfam-B_29595 PB029595 1283-1311 Pfam-B_35798 PB035798 1136-1185 Pfam-B_361 PB000361 1324-1357	BRD4_MOUSE	bromodomain containing 4	BRD4_HUMAN	Histone modification read	#	#	H3K9 H3K14 H4K5 H4K12	#
BRD7	Bromodomain PF00439 140-223 DUF3512 PF12024 286-534 Pfam-B_1543 PB001543 591-649 Pfam-B_64177 PB064177 1-49	BRD7_MOUSE	bromodomain containing 7	BRD7_HUMAN	Histone modification read	#	SWI/SNF BRM-BRG1	H3K9ac H3K14ac H3K8ac	#
BRD8	Bromodomain PF00439 713-799 1112-1195 Pfam-B_19676 PB019676 1-69 Pfam-B_55933 PB055933 71-109	BRD8_MOUSE	bromodomain containing 8	BRD8_HUMAN	Histone modification read	#	SWR NuA4 NuA4-related complex	#	#
BRD9	Bromodomain PF00439 143-228 DUF3512 PF12024 268-505 Pfam-B_8260 PB008260 511-595	BRD9_MOUSE	bromodomain containing 9	BRD9_HUMAN	Histone modification read	#	SWI/SNF BRM-BRG1	H3	#
BRDT	Bromodomain PF00439 36-121 276-364 Pfam-B_11430 PB011430 710-791	BRDT_MOUSE	bromodomain testis-specific	BRDT_HUMAN	Histone modification read	#	#	H4K5ac H4K8ac	#
BRE	BRE PF06113 1-333	BRE_MOUSE	brain and reproductive organ-expressed (TNFRSF1A modulator)	BRE_HUMAN	Histone modification write cofactor	Histone ubiquitination	BRISC BRCC BRCA1-A	#	#
BRMS1	Sds3 PF08598 58-229	BRMS1_MOUSE	breast cancer metastasis suppressor 1	BRMS1_HUMAN	Chromatin remodelling	#	mSin3A	#	#
BRMS1L	Sds3 PF08598 59-227	BRM1L_MOUSE	breast cancer metastasis-suppressor 1-like	BRM1L_HUMAN	Histone modification erase	Histone deacetylation	mSin3A	#	#
BRPF1	Bromodomain PF00439 637-720 EPL1 PF10513 105-255 PHD_2 PF13831 287-321 PWWP PF00855 1083-1198 zf-HC5HC2H_2 PF13832 328-447	#	bromodomain and PHD finger containing 1	BRPF1_HUMAN	Histone modification read	#	MOZ/MORF	H3K36me3	#
BRPF3	Bromodomain PF00439 598-681 EPL1 PF10513 47-194 PHD_2 PF13831 226-260 PWWP PF00855 1074-1189 Pfam-B_5327 PB005327 751-829 zf-HC5HC2H_2 PF13832 267-386	#	bromodomain and PHD finger containing 3	BRPF3_HUMAN	Histone modification write cofactor	Histone acetylation	MOZ/MORF	#	#
BRWD1	Bromodomain PF00439 1166-1252 1322-1405 Pfam-B_18973 PB018973 859-924 Pfam-B_22078 PB022078 2089-2186 Pfam-B_27858 PB027858 1900-2087 Pfam-B_71 PB000071 2238-2318 Pfam-B_8184 PB008184 1821-1898 WD40 PF00400 177-214 218-256 260-302 358-396 458-497	BRWD1_MOUSE	bromodomain and WD repeat domain containing 1	BRWD1_HUMAN	Histone modification read	#	#	H3	#
BRWD3	Bromodomain PF00439 1147-1233 1345-1418 Pfam-B_12397 PB012397 1669-1710 Pfam-B_2569 PB002569 9-97 WD40 PF00400 171-208 212-250 254-296 352-392 455-494 507-540	BRWD3_MOUSE	bromodomain and WD repeat domain containing 3	BRWD3_HUMAN	Histone modification read	#	#	H3	#
BUB1	Mad3_BUB1_I PF08311 4-126 Pkinase PF00069 787-1033	BUB1_MOUSE	BUB1 mitotic checkpoint serine/threonine kinase	BUB1_HUMAN	Histone modification write	Histone phosphorylation	#	H2AS121	H2AS121ph
C11orf30	ENT PF03735 16-88 Pfam-B_10468 PB010468 695-833 Pfam-B_10943 PB010943 985-1113	EMSY_MOUSE	chromosome 11 open reading frame 30	EMSY_HUMAN	Histone modification write cofactor	Histone methylation	#	#	#
C14orf169	Cupin_4 PF08007 215-557 Pfam-B_41208 PB041208 71-139 Pfam-B_47541 PB047541 1-69	NO66_MOUSE	#	NO66_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3 H3K4me1 H3K36me2	H3K4me2 H3K4 H3K36me1
C17orf49	#	BAP18_MOUSE	chromosome 17 open reading frame 49	BAP18_HUMAN	Histone modification read	#	CHD8 MLL2/3 MLL4/WBP7	H3K4me3	#
CARM1	CARM1 PF11531 26-139 PRMT5 PF05185 143-446 Pfam-B_10255 PB010255 449-469 Pfam-B_13059 PB013059 511-606	CARM1_MOUSE	coactivator-associated arginine methyltransferase 1	CARM1_HUMAN	Histone modification write	Histone methylation	#	H3R17	H3R17me H3R17me2a
CBX1	Chromo PF00385 21-70 Chromo_shadow PF01393 115-172	CBX1_MOUSE	chromobox homolog 1	CBX1_HUMAN	Histone modification read	#	#	H3K9me3 H3K27me3	#
CBX2	Chromo PF00385 12-61 Pfam-B_1400 PB001400 249-295	CBX2_MOUSE	chromobox homolog 2	CBX2_HUMAN	Histone modification read	#	PRC1	H3K9me3 H3K27me3	#
CBX3	Chromo PF00385 30-79 Chromo_shadow PF01393 119-176	CBX3_MOUSE	chromobox homolog 3	CBX3_HUMAN	Histone modification read	#	RING2-L3MBTL2 L3MBTL1	H3K9me3	#
CBX4	Chromo PF00385 11-60 Pfam-B_16393 PB016393 481-531 Pfam-B_26041 PB026041 401-479 Pfam-B_8537 PB008537 82-281	CBX4_MOUSE	chromobox homolog 4	CBX4_HUMAN	Histone modification read	#	PRC1	H3K9me3	#
CBX5	Chromo PF00385 20-69 Chromo_shadow PF01393 119-176	CBX5_MOUSE	chromobox homolog 5	CBX5_HUMAN	Histone modification read	#	#	H3K9me H3K27me3	#
CBX6	Chromo PF00385 11-60 Pfam-B_41557 PB041557 291-379 Pfam-B_49897 PB049897 381-410	CBX6_MOUSE	chromobox homolog 6	CBX6_HUMAN	Histone modification read	#	PRC1	H3K9me3 H3K27me3	#
CBX7	Chromo PF00385 11-60	CBX7_MOUSE	chromobox homolog 7	CBX7_HUMAN	Histone modification read	#	PRC1	H3K9me3 H3K27me3	#
CBX8	Chromo PF00385 11-60	CBX8_MOUSE	chromobox homolog 8	CBX8_HUMAN	Histone modification read	#	PRC1	H3K9me3 H3K27me3	#
CCDC101	DUF1325 PF07039 157-289	SGF29_MOUSE	coiled-coil domain containing 101	SGF29_HUMAN	Histone modification read	#	ATAC	H3K4me H3K4me3	#
CDC6	AAA_22 PF13401 190-322 Cdc6_C PF09079 465-545	CDC6_MOUSE	cell division cycle 6	CDC6_HUMAN	Chromatin remodelling	#	#	#	#
CDC73	CDC73 PF05179 233-525	CDC73_MOUSE	cell division cycle 73	CDC73_HUMAN	Histone modification write cofactor	Histone methylation	#	#	#
CDK1	Pkinase PF00069 4-287	CDK1_MOUSE	cyclin-dependent kinase 1	CDK1_HUMAN	Histone modification write	Histone phosphorylation	#	H1	H1ph
CDK2	Pkinase PF00069 4-286	CDK2_MOUSE	cyclin-dependent kinase 2	CDK2_HUMAN	Histone modification write	Histone phosphorylation	#	H1S H1T	H1Sph H1Tph
CDK3	Pkinase PF00069 4-286	CDK3_MOUSE	cyclin-dependent kinase 3	CDK3_HUMAN	Histone modification write	Histone phosphorylation	#	H1	#
CDK5	Pkinase PF00069 4-286	CDK5_MOUSE	cyclin-dependent kinase 5	CDK5_HUMAN	Histone modification write	Histone phosphorylation	#	H1	#
CDK7	Pfam-B_20206 PB020206 301-344 Pkinase PF00069 12-295	CDK7_MOUSE	cyclin-dependent kinase 7	CDK7_HUMAN	Histone modification write	Histone phosphorylation	#	H1	#
CDK9	Pkinase PF00069 19-315	CDK9_MOUSE	cyclin-dependent kinase 9	CDK9_HUMAN	Histone modification cofactor	#	#	#	#
CDK17	Pkinase PF00069 192-473	CDK17_MOUSE	cyclin-dependent kinase 17	CDK17_HUMAN	Histone modification write	Histone phosphorylation	#	H1	#
CDY1	Chromo PF00385 6-57 ECH PF00378 287-535 Pfam-B_51834 PB051834 101-148	#	chromodomain protein Y-linked 1	CDY1_HUMAN	Histone modification write	Histone acetylation	#	H4	#
CDY1B	Chromo PF00385 6-57 ECH PF00378 287-535 Pfam-B_51834 PB051834 101-148	#	chromodomain protein Y-linked 1B	CDY1_HUMAN	Histone modification write	Histone acetylation	#	H4	#
CDY2A	Chromo PF00385 6-57 ECH PF00378 288-536 Pfam-B_51834 PB051834 101-149	#	chromodomain protein Y-linked 2A	CDY2_HUMAN	Histone modification write	Histone acetylation	#	#	#
CDY2B	Chromo PF00385 6-57 ECH PF00378 288-536 Pfam-B_51834 PB051834 101-149	#	chromodomain protein Y-linked 2B	CDY2_HUMAN	Histone modification write	Histone acetylation	#	#	#
CDYL	Chromo PF00385 61-112 ECH PF00378 345-593 Pfam-B_14969 PB014969 136-234	CDYL_MOUSE	chromodomain protein Y-like	CDYL1_HUMAN	Histone modification write	Histone acetylation	#	H4	#
CDYL2	Chromo PF00385 7-57 ECH PF00378 253-501	CDYL2_MOUSE	chromodomain protein Y-like 2	CDYL2_HUMAN	Histone modification read	#	#	H3K9me3	#
CECR2	Bromodomain PF00439 443-526 Pfam-B_13010 PB013010 1-329 Pfam-B_18245 PB018245 800-968 Pfam-B_20164 PB020164 331-419	#	cat eye syndrome chromosome region candidate 2	CECR2_HUMAN	Histone modification read	#	CERF CERF	H2A H3	#
CENPC	CENP-C_C PF11699 856-940 CENP-C_mid PF15620 296-552 CENP_C_N PF15622 7-292	CENPC_MOUSE	centromere protein C	CENPC_HUMAN	DNA modification	DNA methylation	#	C	5mC
CHAF1A	CAF-1_p150 PF11600 266-479 CAF1-p150_C2 PF15539 665-956 CAF1-p150_N PF15557 1-229 CAF1A PF12253 557-635	CAF1A_MOUSE	chromatin assembly factor 1 subunit A (p150)	CAF1A_HUMAN	Chromatin remodelling	#	CAF-1	H3 H4	#
CHAF1B	CAF-1_p60_C PF15512 381-558 WD40 PF00400 10-45 57-94 119-157 161-199 339-372	CAF1B_MOUSE	chromatin assembly factor 1 subunit B (p60)	CAF1B_HUMAN	Chromatin remodelling	#	WINAC CAF-1	H3 H4	#
CHD1	Chromo PF00385 273-355 389-443 DUF4208 PF13907 1400-1500 Helicase_C PF00271 822-902 Pfam-B_182 PB000182 1646-1708 Pfam-B_91833 PB091833 121-162 SNF2_N PF00176 484-765	CHD1_MOUSE	chromodomain helicase DNA binding protein 1	CHD1_HUMAN	Chromatin remodelling	#	#	#	#
CHD1L	Helicase_C PF00271 381-459 Pfam-B_2492 PB002492 468-549 SNF2_N PF00176 49-328	CHD1L_MOUSE	chromodomain helicase DNA binding protein 1-like	CHD1L_HUMAN	Chromatin remodelling	#	#	#	#
CHD2	Chromo PF00385 261-344 378-447 DUF4208 PF13907 1455-1555 Helicase_C PF00271 825-905 Pfam-B_19320 PB019320 1231-1309 Pfam-B_761 PB000761 1111-1229 SNF2_N PF00176 487-768	CHD2_MOUSE	chromodomain helicase DNA binding protein 2	CHD2_HUMAN	Chromatin remodelling	#	#	#	#
CHD3	CHDCT2 PF08074 1735-1907 CHDNT PF08073 147-201 Chromo PF00385 539-574 631-683 DUF1086 PF06461 1363-1519 DUF1087 PF06465 1293-1357 Helicase_C PF00271 1094-1174 PHD PF00628 381-426 458-503 SNF2_N PF00176 739-1035	#	chromodomain helicase DNA binding protein 3	CHD3_HUMAN	Chromatin remodelling	#	NuRD	#	#
CHD4	CHDCT2 PF08074 1724-1896 CHDNT PF08073 163-217 Chromo PF00385 531-577 622-674 DUF1086 PF06461 1366-1523 DUF1087 PF06465 1289-1353 Helicase_C PF00271 1084-1164 PHD PF00628 372-417 451-496 SNF2_N PF00176 729-1025	CHD4_MOUSE	chromodomain helicase DNA binding protein 4	CHD4_HUMAN	Chromatin remodelling	#	NuRD	#	#
CHD5	CHDCT2 PF08074 1731-1903 CHDNT PF08073 146-200 Chromo PF00385 499-537 592-643 DUF1086 PF06461 1377-1531 DUF1087 PF06465 1295-1359 Helicase_C PF00271 1058-1138 PHD PF00628 345-390 418-463 Pfam-B_20089 PB020089 201-334 SNF2_N PF00176 703-999	CHD5_MOUSE	chromodomain helicase DNA binding protein 5	CHD5_HUMAN	Chromatin remodelling	#	#	H3K27me3 H3K4	#
CHD6	BRK PF07533 2400-2441 Chromo PF00385 292-354 375-429 Helicase_C PF00271 817-897 Pfam-B_18962 PB018962 1-49 Pfam-B_23619 PB023619 1691-1909 Pfam-B_71010 PB071010 1911-1953 Pfam-B_761 PB000761 1271-1333 1361-1519 SNF2_N PF00176 464-751	CHD6_MOUSE	chromodomain helicase DNA binding protein 6	CHD6_HUMAN	Chromatin remodelling	#	#	#	#
CHD7	BRK PF07533 2562-2612 2640-2685 Chromo PF00385 800-862 882-935 Helicase_C PF00271 1324-1404 Pfam-B_19729 PB019729 1-188 Pfam-B_19848 PB019848 2351-2469 Pfam-B_2227 PB002227 281-449 Pfam-B_2565 PB002565 1722-1920 Pfam-B_6146 PB006146 2041-2259 Pfam-B_761 PB000761 1622-1720 1966-2035 SNF2_N PF00176 971-1258	CHD7_MOUSE	chromodomain helicase DNA binding protein 7	CHD7_HUMAN	Chromatin remodelling	#	#	#	#
CHD8	BRK PF07533 2308-2353 Chromo PF00385 642-704 724-778 Helicase_C PF00271 1167-1247 Pfam-B_10410 PB010410 1-109 Pfam-B_12479 PB012479 1721-1779 Pfam-B_13819 PB013819 2211-2279 Pfam-B_20709 PB020709 2031-2169 Pfam-B_2565 PB002565 1781-2029 Pfam-B_6146 PB006146 2171-2209 Pfam-B_6192 PB006192 1481-1669 Pfam-B_7386 PB007386 311-493 Pfam-B_8182 PB008182 1411-1479 Pfam-B_8545 PB008545 111-309 SNF2_N PF00176 814-1101	CHD8_MOUSE	chromodomain helicase DNA binding protein 8	CHD8_HUMAN	Chromatin remodelling	#	CHD8 MLL2/3 MLL4/WBP7	H1	#
CHD9	BRK PF07533 2480-2530 2554-2599 Chromo PF00385 690-752 773-827 Helicase_C PF00271 1216-1296 Pfam-B_10410 PB010410 1-89 Pfam-B_1107 PB001107 2701-2729 Pfam-B_15117 PB015117 371-579 Pfam-B_24836 PB024836 1774-1901 Pfam-B_6192 PB006192 1530-1675 Pfam-B_7386 PB007386 231-369 Pfam-B_8182 PB008182 1460-1528 Pfam-B_8545 PB008545 91-229 SNF2_N PF00176 863-1150	CHD9_MOUSE	chromodomain helicase DNA binding protein 9	CHD9_HUMAN	Chromatin remodelling	#	#	#	#
CHEK1	Pkinase PF00069 9-265	CHK1_MOUSE	checkpoint kinase 1	CHK1_HUMAN	Histone modification write	Histone phosphorylation	#	H3.1	H3.1ph
CHRAC1	CBFD_NFYB_HMF PF00808 17-80	CHRC1_MOUSE	chromatin accessibility complex 1	CHRC1_HUMAN	Histone chaperone	#	CHRAC	#	#
CHTOP	FoP_duplication PF13865 171-245	CHTOP_MOUSE	chromatin target of PRMT1	CHTOP_HUMAN	#	#	#	#	#
CHUK	IKKbetaNEMObind PF12179 706-743 Pfam-B_15051 PB015051 300-415 Pkinase PF00069 15-297	IKKA_MOUSE	conserved helix-loop-helix ubiquitous kinase	IKKA_HUMAN	Histone modification write	Histone phosphorylation	#	H3	#
CIR1	Cir_N PF10197 13-49 Pfam-B_16354 PB016354 52-448	CIR1_MOUSE	corepressor interacting with RBPJ 1	CIR1_HUMAN	Histone modification read	#	#	#	#
CIT	CNH PF00780 1597-1868 Pfam-B_11694 PB011694 483-521 Pfam-B_387 PB000387 1354-1412 Pkinase PF00069 97-360 Pkinase_C PF00433 378-424	CTRO_MOUSE	citron rho-interacting serine/threonine kinase	CTRO_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone phosphorylation	#	H3K9	H3K9me
CLNS1A	Pfam-B_77655 PB077655 1-34 Voldacs PF03517 35-165	ICLN_MOUSE	chloride channel nucleotide-sensitive 1A	ICLN_HUMAN	Histone modification write cofactor	Histone methylation	methylosome	#	#
CLOCK	HLH PF00010 35-85 PAS PF00989 109-188 PAS_11 PF14598 273-381 Pfam-B_3081 PB003081 721-839 Pfam-B_7827 PB007827 571-719 Pfam-B_8264 PB008264 382-429	CLOCK_MOUSE	clock circadian regulator	CLOCK_HUMAN	Histone modification write	Histone acetylation	#	H3 H4	#
CRB2	EGF PF00008 112-142 150-180 227-257 324-354 362-392 811-841 1060-1090 Laminin_G_2 PF02210 465-588 900-1033 Pfam-B_3557 PB003557 1199-1283 Pfam-B_79172 PB079172 1119-1197 hEGF PF12661 305-317	CRUM2_MOUSE	crumbs family member 2	CRUM2_HUMAN	Histone modification read	#	#	H4K20	#
CREBBP	Bromodomain PF00439 1094-1180 Creb_binding PF09030 2016-2115 DUF902 PF06001 1191-1232 KAT11 PF08214 1342-1648 KIX PF02172 587-667 Pfam-B_2669 PB002669 2188-2217 Pfam-B_817 PB000817 2353-2401 ZZ PF00569 1701-1742 zf-TAZ PF02135 352-432 1770-1843	CBP_MOUSE	CREB binding protein	CBP_HUMAN	Histone modification write	Histone acetylation	#	#	#
CSNK2A1	Pkinase PF00069 39-324	CSK21_MOUSE	casein kinase 2 alpha 1 polypeptide	CSK21_HUMAN	Histone modification	#	RING2-FBRS	#	#
CSRP2BP	Acetyltransf_1 PF00583 678-752 Pfam-B_6449 PB006449 351-435 Pfam-B_8520 PB008520 1-129	CSR2B_MOUSE	CSRP2 binding protein	CSR2B_HUMAN	Histone modification write	Histone acetylation	ATAC	H4	#
CTBP1	2-Hacid_dh PF00389 30-352 2-Hacid_dh_C PF02826 133-317	CTBP1_MOUSE	C-terminal binding protein 1	CTBP1_HUMAN	Chromatin remodelling	#	LSD-CoREST	#	#
CTBP2	2-Hacid_dh PF00389 36-358 2-Hacid_dh_C PF02826 139-323	CTBP2_MOUSE	C-terminal binding protein 2	CTBP2_HUMAN	Histone modification write cofactor	Histone methylation	#	H3K9	H3K9me H3K9me2
CTCF	Pfam-B_18810 PB018810 671-725 zf-C2H2 PF00096 437-460 zf-C2H2_4 PF13894 555-578 zf-H2C2_2 PF13465 280-305 308-333 336-362 365-389 393-418 481-506 507-534	CTCF_MOUSE	CCCTC-binding factor (zinc finger protein)	CTCF_HUMAN	Chromatin remodelling TF	# TF activator	#	DNA motif	#
CTCFL	Pfam-B_37192 PB037192 1-49 Pfam-B_59982 PB059982 611-659 zf-C2H2 PF00096 428-451 546-568 zf-H2C2_2 PF13465 271-296 299-324 327-353 356-380 384-409 472-497 500-525	CTCFL_MOUSE	CCCTC-binding factor (zinc finger protein)-like	CTCFL_HUMAN	Chromatin remodelling	#	#	#	#
CTR9	Pfam-B_9491 PB009491 5-42 TPR_1 PF00515 163-196 198-231 306-339 342-374 498-530 531-564 681-710 TPR_2 PF07719 451-483	CTR9_MOUSE	CTR9 Paf1/RNA polymerase II complex component	CTR9_HUMAN	Histone modification cofactor	#	#	H3K36	#
CUL1	Cullin PF00888 21-707 Cullin_Nedd8 PF10557 703-770	CUL1_MOUSE	cullin 1	CUL1_HUMAN	Chromatin remodelling cofactor	#	#	H3K9me3 H3K36me3 H1.4K26me3	H3K9 H3K36 H1.4K26
CUL2	Cullin PF00888 14-645 Cullin_Nedd8 PF10557 672-739	CUL2_MOUSE	cullin 2	CUL2_HUMAN	Chromatin remodelling cofactor	#	#	HP1 (Heterochromatin protein 1)	#
CUL3	Cullin PF00888 34-666 Cullin_Nedd8 PF10557 695-762	CUL3_MOUSE	cullin 3	CUL3_HUMAN	Histone modification write	Histone ubiquitination	#	MACROH2A	#
CUL4A	Cullin PF00888 63-661 Cullin_Nedd8 PF10557 688-753	CUL4A_MOUSE	cullin 4A	CUL4A_HUMAN	Histone modification write	Histone ubiquitination	#	H3 H4	#
CUL4B	Cullin PF00888 217-815 Cullin_Nedd8 PF10557 842-907	CUL4B_MOUSE	cullin 4B	CUL4B_HUMAN	Histone modification write	Histone ubiquitination	#	H3 H4	#
CUL5	Cullin PF00888 19-673 Cullin_Nedd8 PF10557 707-774	CUL5_MOUSE	cullin 5	CUL5_HUMAN	DNA modification cofactor	DNA methylation	#	#	#
CXXC1	PHD PF00628 28-76 zf-CXXC PF02008 160-208 zf-CpG_bind_C PF12269 400-636	CXXC1_MOUSE	CXXC finger protein 1	CXXC1_HUMAN	Chromatin remodelling TF	# #	COMPASS	CG DNA motif	#
DAPK3	Pkinase PF00069 13-275	DAPK3_MOUSE	death-associated protein kinase 3	DAPK3_HUMAN	Histone modification write	Histone phosphorylation	#	H3T11	#
DAXX	Daxx PF03344 1-740	DAXX_MOUSE	death-domain associated protein	DAXX_HUMAN	#	#	#	H3.3	#
DDB1	CPSF_A PF03178 788-1099 MMS1_N PF10433 75-546 Pfam-B_431 PB000431 585-732	DDB1_MOUSE	damage-specific DNA binding protein 1 127kDa	DDB1_HUMAN	Histone modification write	Histone ubiquitination	#	H2A	#
DDB2	WD40 PF00400 112-140 232-271 284-316	DDB2_MOUSE	damage-specific DNA binding protein 2 48kDa	DDB2_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	#	#
DDX21	DEAD PF00270 210-385 GUCT PF08152 620-716 Helicase_C PF00271 458-532 Pfam-B_47445 PB047445 1-39	DDX21_MOUSE	DEAD (Asp-Glu-Ala-Asp) box helicase 21	DDX21_HUMAN	RNA modification	#	B-WICH	#	#
DDX50	DEAD PF00270 161-336 GUCT PF08152 571-666 Helicase_C PF00271 409-483	DDX50_MOUSE	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50	DDX50_HUMAN	RNA modification	#	#	#	#
DEK	DEK_C PF08766 321-375 Pfam-B_10960 PB010960 191-269 SAP PF02037 149-183	DEK_MOUSE	DEK proto-oncogene	DEK_HUMAN	Chromatin remodelling	#	B-WICH	H4	#
DMAP1	DMAP1 PF05499 243-407	DMAP1_MOUSE	DNA methyltransferase 1 associated protein 1	DMAP1_HUMAN	Chromatin remodelling	#	NuA4 NuA4-related complex SRCAP	#	#
DNAJC1	DnaJ PF00226 65-126 Myb_DNA-binding PF00249 494-543 Pfam-B_8255 PB008255 367-413	DNJC1_MOUSE	DnaJ (Hsp40) homolog subfamily C member 1	DNJC1_HUMAN	Histone modification write cofactor Histone modification erase cofactor	Histone acetylation Histone deacetylation	#	#	#
DNAJC2	DnaJ PF00226 88-158 Myb_DNA-binding PF00249 451-506 552-600 Pfam-B_24524 PB024524 28-59 Pfam-B_30652 PB030652 1-27	DNJC2_MOUSE	DnaJ (Hsp40) homolog subfamily C member 2	DNJC2_HUMAN	Histone modification read	#	#	H2A	#
DND1	DND1_DSRM PF14709 253-333 RRM_1 PF00076 60-126	DND1_MOUSE	DND microRNA-mediated repression inhibitor 1	DND1_HUMAN	RNA modification	#	#	#	#
DNMT1	BAH PF01426 755-880 931-1100 DMAP_binding PF06464 16-105 DNA_methylase PF00145 1139-1594 DNMT1-RFD PF12047 399-534 zf-CXXC PF02008 645-691	DNMT1_MOUSE	DNA (cytosine-5-)-methyltransferase 1	DNMT1_HUMAN	DNA modification	DNA methylation	#	dhC	dhU
DNMT3A	DNA_methylase PF00145 634-776 PWWP PF00855 290-375	DNM3A_MOUSE	DNA (cytosine-5-)-methyltransferase 3 alpha	DNM3A_HUMAN	DNA modification	DNA methylation	#	dhC	dhU
DNMT3B	DNA_methylase PF00145 575-725 PWWP PF00855 223-308	DNM3B_MOUSE	DNA (cytosine-5-)-methyltransferase 3 beta	DNM3B_HUMAN	DNA modification	DNA methylation	#	dhC	dhU
DNMT3L	Pfam-B_139748 PB139748 181-229 Pfam-B_41249 PB041249 91-179	DNM3L_MOUSE	DNA (cytosine-5-)-methyltransferase 3-like	DNM3L_HUMAN	Histone modification read	#	#	H3K4	#
DNTTIP2	Fcf2 PF08698 635-731	TDIF2_MOUSE	deoxynucleotidyltransferase terminal interacting protein 2	TDIF2_HUMAN	Chromatin remodelling	#	#	H2A H2B	#
DOT1L	DOT1 PF08123 115-317 Pfam-B_30738 PB030738 501-539	-	DOT1-like histone H3K79 methyltransferase	DOT1L_HUMAN	Histone modification write	Histone methylation	#	H3K79	#
DPF1	PHD PF00628 256-311 310-368 Pfam-B_77905 PB077905 1-37 Requiem_N PF14051 38-111	DPF1_MOUSE	D4 zinc and double PHD fingers family 1	DPF1_HUMAN	Chromatin remodelling cofactor	#	nBAF SWI/SNF BRM-BRG1	#	#
DPF2	PHD PF00628 272-330 329-376 Requiem_N PF14051 12-85	REQU_MOUSE	D4 zinc and double PHD fingers family 2	REQU_HUMAN	Chromatin remodelling	#	SWI/SNF BRM-BRG1	#	#
DPF3	PHD PF00628 261-319 318-366 Requiem_N PF14051 12-85	DPF3_MOUSE	D4 zinc and double PHD fingers family 3	DPF3_HUMAN	Chromatin remodelling	#	BAF nBAF SWI/SNF BRM-BRG1	H3 H4	#
DPPA3	PGC7_Stella PF15549 1-155	DPPA3_MOUSE	developmental pluripotency associated 3	DPPA3_HUMAN	Histone modification read	#	#	H3K9me2	#
DPY30	Dpy-30 PF05186 52-93 Pfam-B_28037 PB028037 1-51	DPY30_MOUSE	dpy-30 homolog (C. elegans)	DPY30_HUMAN	Histone modification write cofactor	Histone methylation	COMPASS Menin-associated_HMT MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7 COMPASS-like MLL3 4	#	#
DR1	CBFD_NFYB_HMF PF00808 11-75	NC2B_MOUSE	down-regulator of transcription 1 TBP-binding (negative cofactor 2)	NC2B_HUMAN	Histone chaperone	#	ATAC	#	#
DTX3L	Pfam-B_11420 PB011420 311-389 706-737 zf-RING_2 PF13639 559-600	DTX3L_MOUSE	deltex 3 like E3 ubiquitin ligase	DTX3L_HUMAN	Histone modification write	Histone ubiquitination	#	H4K91	#
DZIP3	Pfam-B_10362 PB010362 531-619 Pfam-B_5525 PB005525 201-419 Pfam-B_5636 PB005636 1-199 Pfam-B_8501 PB008501 621-773 Pfam-B_8729 PB008729 421-529 zf-RING_2 PF13639 1146-1188	DZIP3_MOUSE	DAZ interacting zinc finger protein 3	DZIP3_HUMAN	Histone modification write	Histone ubiquitination	#	H2AK119	H2AK119ub
E2F6	E2F_TDP PF02319 63-128	E2F6_MOUSE	E2F transcription factor 6	E2F6_HUMAN	TF	TF repressor	RING2-L3MBTL2 CHD8 MLL2/3 MLL4/WBP7	DNA motif	#
EED	Pfam-B_26038 PB026038 1-39 Pfam-B_6684 PB006684 265-359 WD40 PF00400 180-219 231-264	EED_MOUSE	embryonic ectoderm development	EED_HUMAN	Polycomb group (PcG) protein	#	PRC2	#	#
EHMT1	Ank_2 PF12796 742-836 810-903 910-998 Ank_4 PF13637 773-826 839-893 Pfam-B_28560 PB028560 1-98 Pre-SET PF05033 1013-1118 SET PF00856 1137-1243	EHMT1_MOUSE	euchromatic histone-lysine N-methyltransferase 1	EHMT1_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me1 H3K9me2
EHMT2	Ank PF00023 684-716 717-748 750-783 784-816 818-849 850-882 Pfam-B_9355 PB009355 34-359 Pre-SET PF05033 925-1030 SET PF00856 1049-1155	EHMT2_MOUSE	euchromatic histone-lysine N-methyltransferase 2	EHMT2_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me1 H3K9me2
EID1	Pfam-B_5729 PB005729 1-159	EID1_MOUSE	EP300 interacting inhibitor of differentiation 1	EID1_HUMAN	Histone modification write cofactor	Histone acetylation	#	#	#
EID2	Pfam-B_42536 PB042536 111-199 Pfam-B_7728 PB007728 1-109 201-234	EID2_MOUSE	EP300 interacting inhibitor of differentiation 2	EID2_HUMAN	Histone modification write cofactor	Histone acetylation	#	#	#
EID2B	#	#	EP300 interacting inhibitor of differentiation 2B	EID2B_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ELP2	WD40 PF00400 48-91 99-143 197-237 274-320 378-416 557-587 604-642 662-697	ELP2_MOUSE	elongator acetyltransferase complex subunit 2	ELP2_HUMAN	Histone modification write cofactor	Histone acetylation	Pol2 elongator	#	#
ELP3	Acetyltransf_1 PF00583 441-536 Pfam-B_13823 PB013823 1-49 Radical_SAM PF04055 96-305	ELP3_MOUSE	elongator acetyltransferase complex subunit 3	ELP3_HUMAN	Histone modification write	Histone acetylation	Pol2 elongator	H3 H4?	#
ELP4	PAXNEB PF05625 27-424	ELP4_MOUSE	elongator acetyltransferase complex subunit 4	ELP4_HUMAN	Histone modification write cofactor	Histone acetylation	Pol2 elongator	#	#
ELP5	Elong_Iki1 PF10483 17-298	ELP5_MOUSE	elongator acetyltransferase complex subunit 5	ELP5_HUMAN	Histone modification write cofactor	Histone acetylation	Pol2 elongator	H3K14 H4K8	#
ELP6	DUF2348 PF09807 1-251	ELP6_MOUSE	elongator acetyltransferase complex subunit 6	ELP6_HUMAN	Histone modification write cofactor	Histone acetylation	Pol2 elongator	#	#
ENY2	EnY2 PF10163 11-96	ENY2_MOUSE	enhancer of yellow 2 homolog (Drosophila)	ENY2_HUMAN	Histone modification erase cofactor	Histone ubiquitination	SAGA	#	#
EP300	Bromodomain PF00439 1058-1144 Creb_binding PF09030 1990-2099 DUF902 PF06001 1155-1196 KAT11 PF08214 1306-1612 KIX PF02172 566-646 Pfam-B_15526 PB015526 1-129 Pfam-B_817 PB000817 2317-2349 ZZ PF00569 1664-1705 zf-TAZ PF02135 336-416 1733-1806	EP300_MOUSE	E1A binding protein p300	EP300_HUMAN	Histone modification write	Histone acetylation	#	H2A H2B H3 H4	#
EP400	HSA PF07529 800-871 Helicase_C PF00271 1932-2014 Pfam-B_18422 PB018422 1887-1923 SNF2_N PF00176 1094-1374	EP400_MOUSE	E1A binding protein p400	EP400_HUMAN	Chromatin remodelling Histone modification write	# Histone acetylation	SWR NuA4 NuA4-related complex	#	#
EPC1	EPL1 PF10513 6-149 E_Pc_C PF06752 582-836	EPC1_MOUSE	enhancer of polycomb homolog 1 (Drosophila)	EPC1_HUMAN	Polycomb group (PcG) protein	#	NuA4 Piccolo_NuA4 NuA4-related complex	#	#
EPC2	EPL1 PF10513 6-149 E_Pc_C PF06752 577-807 Pfam-B_18248 PB018248 432-544 Pfam-B_19406 PB019406 370-415	EPC2_MOUSE	enhancer of polycomb homolog 2 (Drosophila)	EPC2_HUMAN	Chromatin remodelling	#	#	#	#
ERBB4	Furin-like PF00757 176-335 GF_recep_IV PF14843 502-634 Pfam-B_10445 PB010445 1236-1306 Pkinase_Tyr PF07714 718-974 Recep_L_domain PF01030 55-167 358-478	ERBB4_MOUSE	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4	ERBB4_HUMAN	Histone modification cofactor	#	#	H3K9me3	#
ERCC6	Helicase_C PF00271 873-952 Pfam-B_58020 PB058020 1-49 SNF2_N PF00176 510-812	#	excision repair cross-complementation group 6	ERCC6_HUMAN	Chromatin remodelling	#	B-WICH	#	#
EXOSC1	ECR1_N PF14382 7-41 EXOSC1 PF10447 64-135	EXOS1_MOUSE	exosome component 1	EXOS1_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC2	ECR1_N PF14382 26-64	EXOS2_MOUSE	exosome component 2	EXOS2_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC3	Pfam-B_7181 PB007181 221-267	EXOS3_MOUSE	exosome component 3	EXOS3_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC4	Pfam-B_25613 PB025613 221-243 RNase_PH PF01138 21-152 RNase_PH_C PF03725 155-220	EXOS4_MOUSE	exosome component 4	EXOS4_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC5	RNase_PH PF01138 27-147 RNase_PH_C PF03725 150-216	EXOS5_MOUSE	exosome component 5	EXOS5_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC6	RNase_PH PF01138 35-175	EXOS6_MOUSE	exosome component 6	EXOS6_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC7	RNase_PH PF01138 31-166 RNase_PH_C PF03725 196-262	EXOS7_MOUSE	exosome component 7	EXOS7_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC8	RNase_PH PF01138 31-166 RNase_PH_C PF03725 191-258	EXOS8_MOUSE	exosome component 8	EXOS8_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EXOSC9	RNase_PH PF01138 31-163 RNase_PH_C PF03725 189-256	EXOS9_MOUSE	exosome component 9	EXOS9_HUMAN	Scaffold protein RNA modification	# RNA degradation	RNA exosome	#	#
EYA1	Pfam-B_10178 PB010178 530-586 Pfam-B_3150 PB003150 209-513	EYA1_MOUSE	EYA transcriptional coactivator and phosphatase 1	EYA1_HUMAN	Histone modification erase	Histone phosphorylation	#	H2AXT142	#
EYA2	#	EYA2_MOUSE	EYA transcriptional coactivator and phosphatase 2	EYA2_HUMAN	Histone modification erase	Histone phosphorylation	#	H2AXT142	#
EYA3	#	EYA3_MOUSE	EYA transcriptional coactivator and phosphatase 3	EYA3_HUMAN	Histone modification erase	Histone phosphorylation	#	H2AXT142	#
EYA4	Pfam-B_6035 PB006035 96-142	EYA4_MOUSE	EYA transcriptional coactivator and phosphatase 4	EYA4_HUMAN	Histone modification erase	Histone phosphorylation	#	H2AXY142ph	H2AXY142
EZH1	EZH2_WD-Binding PF11616 39-68 SET PF00856 624-728	EZH1_MOUSE	enhancer of zeste 1 polycomb repressive complex 2 subunit	EZH1_HUMAN	Histone modification write Polycomb group (PcG) protein	Histone methylation #	PRC2	H3K27	H3K27me1 H3K27me2 H3K27me3
EZH2	EZH2_WD-Binding PF11616 39-68 SET PF00856 623-727	EZH2_MOUSE	enhancer of zeste 2 polycomb repressive complex 2 subunit	EZH2_HUMAN	Histone modification write Polycomb group (PcG) protein	Histone methylation #	PRC2	H3K27	H3K27me1 H3K27me2 H3K27me3
FAM175A	Pfam-B_8506 PB008506 1-175	F175A_MOUSE	family with sequence similarity 175 member A	F175A_HUMAN	Scaffold protein	#	BRCA1-A	#	#
FAM175B	Pfam-B_24421 PB024421 331-390	F175B_MOUSE	family with sequence similarity 175 member B	F175B_HUMAN	Histone modification erase cofactor	Histone ubiquitination	BRISC	H2AK63	H2AK63ub
FBL	Fibrillarin PF01269 88-315	FBRL_MOUSE	fibrillarin	FBRL_HUMAN	Histone modification write	Histone methylation	#	H2AQ104	H2AQ104me
FBRS	Auts2 PF15336 82-282 Pfam-B_58582 PB058582 283-359	FBRS_MOUSE	fibrosin	FBRS_HUMAN	Histone modification	#	RING2-FBRS	#	#
FBRSL1	Auts2 PF15336 587-791 Pfam-B_17807 PB017807 439-487 Pfam-B_187339 PB187339 41-131 Pfam-B_52362 PB052362 164-412	#	fibrosin-like 1	FBSL_HUMAN	Histone modification	#	RING2-FBRS	#	#
FOXA1	Fork_head PF00250 170-265 Fork_head_N PF08430 17-169 HNF_C PF09354 397-461	FOXA1_MOUSE	forkhead box A1	FOXA1_HUMAN	Chromatin remodelling TF	# #	#	DNA motif	#
FOXO1	Fork_head PF00250 127-268 Pfam-B_12765 PB012765 601-653 Pfam-B_39024 PB039024 1-49	FOXO1_MOUSE	forkhead box O1	FOXO1_HUMAN	TF	#	#	DNA motif H3 H4	#
FOXP1	Fork_head PF00250 465-555 Pfam-B_24123 PB024123 1-79	FOXP1_MOUSE	forkhead box P1	FOXP1_HUMAN	TF	#	#	DNA motif	#
FOXP2	Fork_head PF00250 504-593 Pfam-B_4008 PB004008 240-308	FOXP2_MOUSE	forkhead box P2	FOXP2_HUMAN	TF	#	#	DNA motif	#
FOXP3	Fork_head PF00250 337-426	FOXP3_MOUSE	forkhead box P3	FOXP3_HUMAN	TF	#	#	DNA motif	#
FOXP4	Fork_head PF00250 467-555 Pfam-B_22084 PB022084 1-155 Pfam-B_23482 PB023482 569-647 Pfam-B_4008 PB004008 201-230	FOXP4_MOUSE	forkhead box P4	FOXP4_HUMAN	TF	#	#	DNA motif	#
GADD45A	Ribosomal_L7Ae PF01248 21-123	GA45A_MOUSE	growth arrest and DNA-damage-inducible alpha	GA45A_HUMAN	Chromatin remodelling	#	#	H2A H2B H3 H4	#
GADD45B	Ribosomal_L7Ae PF01248 21-121	GA45B_MOUSE	growth arrest and DNA-damage-inducible beta	GA45B_HUMAN	Chromatin remodelling	#	#	H2A H2B H3 H4	#
GADD45G	Ribosomal_L7Ae PF01248 24-113	GA45G_MOUSE	growth arrest and DNA-damage-inducible gamma	GA45G_HUMAN	Chromatin remodelling	#	#	H2A H2B H3 H4	#
GATAD1	GATA PF00320 9-36 Pfam-B_13145 PB013145 175-216 Pfam-B_17231 PB017231 235-263	GATD1_MOUSE	GATA zinc finger domain containing 1	GATD1_HUMAN	Histone modification read	#	#	H3K4me3	#
GATAD2A	Pfam-B_2058 PB002058 1-79	P66A_MOUSE	GATA zinc finger domain containing 2A	P66A_HUMAN	Histone modification read	#	NuRD	H2A H2B H3 H4	#
GATAD2B	GATA PF00320 420-454	P66B_MOUSE	GATA zinc finger domain containing 2B	P66B_HUMAN	Histone modification read	#	NuRD	H2A H2B H3 H4	#
GFI1	LIM PF00412 228-283 287-342 346-401 405-460 Paxillin PF03535 6-135	GFI1_MOUSE	growth factor independent 1 transcription repressor	GFI1_HUMAN	Chromatin remodelling	#	#	#	#
GFI1B	zf-C2H2 PF00096 220-242 zf-H2C2_2 PF13465 177-203 262-287 290-314	GFI1B_MOUSE	growth factor independent 1B transcription repressor	GFI1B_HUMAN	Histone modification cofactor	#	#	#	#
GLYR1	NAD_binding_11 PF14833 430-551 NAD_binding_2 PF03446 267-429 PWWP PF00855 6-89	GLYR1_MOUSE	glyoxylate reductase 1 homolog (Arabidopsis)	GLYR1_HUMAN	Histone modification read	#	#	H3K4me3	#
GSE1	DUF3736 PF12540 70-203 731-874	GSE1_MOUSE	Gse1 coiled-coil protein	GSE1_HUMAN	Histone modification erase	Histone acetylation	BHC LSD-CoREST	#	#
GSG2	DUF3635 PF12330 708-797 Pfam-B_41097 PB041097 111-310 Pfam-B_49843 PB049843 1-109 Pkinase PF00069 484-699	HASP_MOUSE	germ cell associated 2 (haspin)	HASP_HUMAN	Histone modification write	Histone phosphorylation	#	H3T3	H3T3ph
GTF2I	GTF2I PF02946 112-187 361-436 466-541 571-646 733-808 868-943	GTF2I_MOUSE	general transcription factor IIi	GTF2I_HUMAN	TF	#	BHC	DNA motif	#
GTF3C4	TFIIIC_delta PF12657 61-254 zf-TFIIIC PF12660 733-822	TF3C4_MOUSE	general transcription factor IIIC polypeptide 4 90kDa	TF3C4_HUMAN	Histone modification write	Histone acetylation	#	H3	#
HAT1	Hat1_N PF10394 26-187	HAT1_MOUSE	histone acetyltransferase 1	HAT1_HUMAN	Histone modification write	Histone acetylation	#	H4 H2A	#
HCFC1	Kelch_1 PF01344 32-71 Kelch_3 PF13415 91-145 146-208 215-263 264-330 Pfam-B_49758 PB049758 381-598	HCFC1_MOUSE	host cell factor C1	HCFC1_HUMAN	Chromatin remodelling	#	NSL COMPASS MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7	#	#
HCFC2	Kelch_1 PF01344 244-301 Kelch_3 PF13415 205-253 Kelch_5 PF13854 312-356	HCFC2_MOUSE	host cell factor C2	HCFC2_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	MLL-HCF CHD8 MLL2/3 MLL4/WBP7	H3	#
HDAC1	Hist_deacetyl PF00850 18-320 Pfam-B_22185 PB022185 444-478	HDAC1_MOUSE	histone deacetylase 1	HDAC1_HUMAN	Histone modification erase	Histone acetylation	SWI/SNF_Brm NuRD BHC MeCP1 mSin3A core HDAC mSin3A-like complex RING2-L3MBTL2 CREST-BRG1 LSD-CoREST	H3 H4	#
HDAC2	Hist_deacetyl PF00850 19-321 Pfam-B_46198 PB046198 351-449	HDAC2_MOUSE	histone deacetylase 2	HDAC2_HUMAN	Histone modification erase	Histone acetylation	SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm NuRD BHC MeCP1 mSin3A core HDAC mSin3A-like complex RING2-L3MBTL2 LSD-CoREST	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC3	Hist_deacetyl PF00850 11-315 Pfam-B_3137 PB003137 353-383	HDAC3_MOUSE	histone deacetylase 3	HDAC3_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC4	Arb2 PF09757 1000-1059 HDAC4_Gln PF12203 61-152 Hist_deacetyl PF00850 664-993	HDAC4_MOUSE	histone deacetylase 4	HDAC4_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC5	HDAC4_Gln PF12203 66-133 Hist_deacetyl PF00850 693-1023	HDAC5_MOUSE	histone deacetylase 5	HDAC5_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC6	Hist_deacetyl PF00850 95-403 489-799 zf-UBP PF02148 1133-1195	HDAC6_MOUSE	histone deacetylase 6	HDAC6_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC7	Hist_deacetyl PF00850 530-860 Pfam-B_5922 PB005922 1-148	HDAC7_MOUSE	histone deacetylase 7	HDAC7_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC8	Hist_deacetyl PF00850 21-323 Pfam-B_15628 PB015628 324-375	HDAC8_MOUSE	histone deacetylase 8	HDAC8_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC9	HDAC4_Gln PF12203 36-124 Hist_deacetyl PF00850 643-973 Pfam-B_5353 PB005353 577-624	HDAC9_MOUSE	histone deacetylase 9	HDAC9_HUMAN	Histone modification erase	Histone acetylation	#	H3Kac H4Kac	H3K H4K
HDAC10	Hist_deacetyl PF00850 13-322	HDA10_MOUSE	histone deacetylase 10	HDA10_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDAC11	Hist_deacetyl PF00850 23-320	HDA11_MOUSE	histone deacetylase 11	HDA11_HUMAN	Histone modification erase	Histone acetylation	#	H2AKac H2BKac H3Kac H4Kac	H2AK H2BK H3K H4K
HDGF	PWWP PF00855 10-92	HDGF_MOUSE	hepatoma-derived growth factor	HDGF_HUMAN	Chromatin remodelling TF	# TF repressor	#	DNA motif	#
HELLS	Helicase_C PF00271 633-712 SNF2_N PF00176 226-577	HELLS_MOUSE	helicase lymphoid-specific	HELLS_HUMAN	Chromatin remodelling	#	#	#	#
HIF1AN	Cupin_8 PF13621 48-302	HIF1N_MOUSE	hypoxia inducible factor 1 alpha subunit inhibitor	HIF1N_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
HINFP	Pfam-B_17110 PB017110 1-103 zf-C2H2 PF00096 255-278 345-368 zf-C2H2_4 PF13894 229-254 zf-H2C2_2 PF13465 185-210	HINFP_MOUSE	histone H4 transcription factor	HINFP_HUMAN	Histone modification read TF TF	# TF activator TF repressor	#	H4 DNA motif	#
HIRA	HIRA_B PF09453 448-471 Hira PF07569 763-962 Pfam-B_18560 PB018560 963-1015 WD40 PF00400 5-44 60-98 121-159 164-202 258-312	HIRA_MOUSE	histone cell cycle regulator	HIRA_HUMAN	Histone modification read	#	#	H2B H4	#
HIRIP3	CHZ PF09649 484-520	HIRP3_MOUSE	HIRA interacting protein 3	HIRP3_HUMAN	Histone modification read	#	#	H2A H3	#
HJURP	HJURP_C PF12347 409-471 554-614 HJURP_mid PF12346 271-386 Pfam-B_631 PB000631 682-746 Scm3 PF10384 16-77	HJURP_MOUSE	Holliday junction recognition protein	HJURP_HUMAN	Histone chaperone	#	#	H4	#
HLCS	BPL_C PF02237 669-718 BPL_LplA_LipB PF03099 471-603 Pfam-B_33359 PB033359 244-405 Pfam-B_35799 PB035799 407-469	BPL1_MOUSE	holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)	BPL1_HUMAN	Histone modification write	#	#	H1 H2A H2B H4	#
HLTF	HIRAN PF08797 60-155 Helicase_C PF00271 870-950 SNF2_N PF00176 243-722 zf-RING_2 PF13639 758-801	HLTF_MOUSE	helicase-like transcription factor	HLTF_HUMAN	Chromatin remodelling cofactor	#	#	#	#
HMG20A	HMG_box PF00505 103-171	HM20A_MOUSE	high mobility group 20A	HM20A_HUMAN	Chromatin remodelling cofactor	#	LSD-CoREST	H3K4	#
HMG20B	HMG_box PF00505 70-138 Pfam-B_10576 PB010576 211-315	HM20B_MOUSE	high mobility group 20B	HM20B_HUMAN	Chromatin remodelling	#	BHC LSD-CoREST	#	#
HMGB1	HMG_box PF00505 95-163 HMG_box_2 PF09011 6-79	HMGB1_MOUSE	high mobility group box 1	HMGB1_HUMAN	Chromatin remodelling	#	#	#	#
HMGN1	HMG14_17 PF01101 2-96	HMGN1_MOUSE	high mobility group nucleosome binding domain 1	HMGN1_HUMAN	Chromatin remodelling	#	#	H1	#
HMGN2	HMG14_17 PF01101 2-90	HMGN2_MOUSE	high mobility group nucleosomal binding domain 2	HMGN2_HUMAN	Chromatin remodelling	#	#	H1	#
HMGN3	HMG14_17 PF01101 2-98	HMGN3_MOUSE	high mobility group nucleosomal binding domain 3	HMGN3_HUMAN	Chromatin remodelling	#	#	H1	#
HMGN4	HMG14_17 PF01101 2-90	#	high mobility group nucleosomal binding domain 4	HMGN4_HUMAN	Chromatin remodelling	#	#	H1	#
HMGN5	HMG14_17 PF01101 2-102	HMGN5_MOUSE	high mobility group nucleosome binding domain 5	HMGN5_HUMAN	Chromatin remodelling	#	#	H1	#
HP1BP3	Linker_histone PF00538 157-232 260-330 341-412	HP1B3_MOUSE	heterochromatin protein 1 binding protein 3	HP1B3_HUMAN	Chromatin remodelling	#	#	#	#
HR	JmjC PF02373 1026-1140 Pfam-B_40014 PB040014 312-431 Pfam-B_80075 PB080075 181-289	HAIR_MOUSE	hair growth associated	HAIR_HUMAN	Histone modification erase	Histone methylation	#	H3K9me1 H3K9me2	H3K9
HSPA1A	HSP70 PF00012 6-612	HS71A_MOUSE	heat shock 70kDa protein 1A	HSP71_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	#	#
HSPA1B	HSP70 PF00012 6-612	HS71A_MOUSE	heat shock 70kDa protein 1B	HSP71_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	#	#
HUWE1	DUF4414 PF14377 2968-3079 DUF908 PF06012 89-370 DUF913 PF06025 429-815 HECT PF00632 4067-4374 Pfam-B_13571 PB013571 3944-3965 Pfam-B_15798 PB015798 3091-3191 Pfam-B_20712 PB020712 2429-2459 Pfam-B_6870 PB006870 3966-4021 UBA PF00627 1317-1352 WWE PF02825 1611-1679	HUWE1_MOUSE	HECT UBA and WWE domain containing 1 E3 ubiquitin protein ligase	HUWE1_HUMAN	Histone modification write	Histone ubiquitination	#	H3K9	#
IKBKAP	IKI3 PF04762 1-954 Pfam-B_8846 PB008846 1048-1212	ELP1_MOUSE	inhibitor of kappa light polypeptide gene enhancer in B-cells kinase complex-associated protein	ELP1_HUMAN	Scaffold protein	#	Pol2 elongator	RNA	#
IKZF1	zf-H2C2_2 PF13465 131-156 159-184 187-212	IKZF1_MOUSE	IKAROS family zinc finger 1 (Ikaros)	IKZF1_HUMAN	Chromatin remodelling TF	# #	#	DNA motif	#
IKZF3	Pfam-B_2031 PB002031 67-110 zf-C2H2_4 PF13894 480-504 zf-H2C2_2 PF13465 132-157 160-183 188-213	IKZF3_MOUSE	IKAROS family zinc finger 3 (Aiolos)	IKZF3_HUMAN	TF	#	#	DNA motif	#
ING1	ING PF12998 173-256 PHD PF00628 355-402 Pfam-B_837 PB000837 51-89	ING1_MOUSE	inhibitor of growth family member 1	ING1_HUMAN	Histone modification read	#	#	H3K4me3	#
ING2	ING PF12998 26-125 PHD PF00628 214-261	ING2_MOUSE	inhibitor of growth family member 2	ING2_HUMAN	Histone modification read	#	mSin3A-like complex	H3K4me3	#
ING3	ING PF12998 2-104 PHD PF00628 362-409	ING3_MOUSE	inhibitor of growth family member 3	ING3_HUMAN	Chromatin remodelling Histone modification write cofactor	# Histone acetylation	SWR NuA4 Piccolo_NuA4	H2A H4	#
ING4	ING PF12998 5-107 PHD PF00628 198-245	ING4_MOUSE	inhibitor of growth family member 4	ING4_HUMAN	Histone modification read	#	HBO1	H3K4me3	#
ING5	ING PF12998 5-107 PHD PF00628 188-235	ING5_MOUSE	inhibitor of growth family member 5	ING5_HUMAN	Histone modification read	#	HBO1 MOZ/MORF	H3K4me3 H3K4me2	#
INO80	DBINO PF13892 270-410 Helicase_C PF00271 1135-1214 Pfam-B_16799 PB016799 1435-1475 SNF2_N PF00176 521-822	INO80_MOUSE	INO80 complex subunit	INO80_HUMAN	Chromatin remodelling	#	Ino80	#	#
INO80B	PAPA-1 PF04795 211-293 zf-HIT PF04438 305-336	IN80B_MOUSE	INO80 complex subunit B	IN80B_HUMAN	Chromatin remodelling cofactor	#	Ino80	#	#
INO80C	YL1_C PF08265 141-170	IN80C_MOUSE	INO80 complex subunit C	IN80C_HUMAN	Chromatin remodelling cofactor	#	Ino80 CHD8 MLL2/3 MLL4/WBP7	#	#
INO80D	Pfam-B_14282 PB014282 588-622 zf-C3Hc3H PF13891 16-80 446-512	IN80D_MOUSE	INO80 complex subunit D	IN80D_HUMAN	Chromatin remodelling cofactor	#	Ino80	#	#
INO80E	#	#	INO80 complex subunit E	IN80E_HUMAN	Chromatin remodelling cofactor	#	#	#	#
JADE1	EPL1 PF10513 29-181 PHD_2 PF13831 217-251 zf-HC5HC2H_2 PF13832 256-368	JADE1_MOUSE	jade family PHD finger 1	JADE1_HUMAN	Histone modification write	Histone acetylation	HBO1	H3 H4	H3ac H4ac
JADE2	EPL1 PF10513 39-177 PHD_2 PF13831 213-247 Pfam-B_23296 PB023296 631-669 zf-HC5HC2H_2 PF13832 252-364	JADE2_MOUSE	jade family PHD finger 2	JADE2_HUMAN	Histone modification write	Histone acetylation	HBO1	H3 H4	H3ac H4ac
JADE3	EPL1 PF10513 30-178 PHD PF00628 202-249 zf-HC5HC2H_2 PF13832 253-365	JADE3_MOUSE	jade family PHD finger 3	JADE3_HUMAN	Histone modification write	Histone acetylation	HBO1	H3 H4	H3ac H4ac
JAK2	Pkinase_Tyr PF07714 545-805 849-1123 SH2 PF00017 400-481	JAK2_MOUSE	Janus kinase 2	JAK2_HUMAN	Histone modification write	Histone phosphorylation	#	H3T41	H3T41ph
JARID2	ARID PF01388 618-709 JmjC PF02373 916-1031 JmjN PF02375 558-591 Pfam-B_728 PB000728 1-122 zf-C5HC2 PF02928 1139-1193	JARD2_MOUSE	jumonji AT rich interactive domain 2	JARD2_HUMAN	Histone modification write cofactor	Histone methylation	PRC2	H3K27 H3K9	#
JDP2	bZIP_1 PF00170 70-131	JDP2_MOUSE	Jun dimerization protein 2	JDP2_HUMAN	Chromatin remodelling Histone modification erase cofactor	# Histone acetylation	#	#	#
JMJD1C	JmjC PF02373 2381-2481 Pfam-B_14856 PB014856 2090-2122 Pfam-B_15350 PB015350 2148-2224 Pfam-B_16501 PB016501 1889-1927 Pfam-B_17329 PB017329 541-947 Pfam-B_19453 PB019453 1929-2023 Pfam-B_2770 PB002770 220-524 Pfam-B_63706 PB063706 1-119	JHD2C_MOUSE	jumonji domain containing 1C	JHD2C_HUMAN	Histone modification erase	Histone methylation	#	H3K9me	H3K9
JMJD6	JmjC PF02373 174-288 Pfam-B_22969 PB022969 1-39	JMJD6_MOUSE	jumonji domain containing 6	JMJD6_HUMAN	Histone modification erase	Histone methylation	#	H3R2me H4R3me	H3R2 H4R3
KANSL1	PEHE PF15275 885-1035 Pfam-B_14811 PB014811 571-639 Pfam-B_19390 PB019390 431-469 Pfam-B_2194 PB002194 135-403 Pfam-B_6892 PB006892 471-569	KANL1_MOUSE	KAT8 regulatory NSL complex subunit 1	KANL1_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	NSL CHD8 MLL2/3 MLL4/WBP7	H4	H4ac
KANSL2	Pfam-B_21577 PB021577 1-25 zf-C3Hc3H PF13891 27-93 300-365	KANL2_MOUSE	KAT8 regulatory NSL complex subunit 2	KANL2_HUMAN	Histone modification write cofactor	Histone acetylation	NSL	H5	H4ac
KANSL3	Abhydrolase_5 PF12695 287-436 Pfam-B_10092 PB010092 521-544 Pfam-B_8995 PB008995 545-589	KANL3_MOUSE	KAT8 regulatory NSL complex subunit 3	KANL3_HUMAN	Histone modification write cofactor	Histone acetylation	NSL	H6	H4ac
KAT2A	Acetyltransf_1 PF00583 553-628 Bromodomain PF00439 737-820 PCAF_N PF06466 86-337 Pfam-B_10717 PB010717 1-67	KAT2A_MOUSE	K(lysine) acetyltransferase 2A	KAT2A_HUMAN	Histone modification write	Histone acetylation	TFTC-HAT SAGA ATAC STAGA	#	#
KAT2B	Acetyltransf_7 PF13508 541-624 Bromodomain PF00439 732-815 PCAF_N PF06466 74-327 Pfam-B_358817 PB358817 339-381	KAT2B_MOUSE	K(lysine) acetyltransferase 2B	KAT2B_HUMAN	Histone modification write	Histone acetylation	#	#	#
KAT5	MOZ_SAS PF01853 285-477 Tudor-knot PF11717 7-65	KAT5_MOUSE	K(lysine) acetyltransferase 5	KAT5_HUMAN	Histone modification write	Histone acetylation	SWR NuA4 Piccolo_NuA4	H2AK5 H3K14 H4K5 H4K8 H4K12 H4K16	H2AK5ac H3K14ac H4K5ac H4K8ac H4K12ac H4K16ac
KAT6A	MOZ_SAS PF01853 562-749 PHD PF00628 208-265 264-313 Pfam-B_19382 PB019382 1-84 Pfam-B_21350 PB021350 1011-1048 Pfam-B_25985 PB025985 1056-1116 Pfam-B_3468 PB003468 1648-1699 Pfam-B_6470 PB006470 1487-1601	KAT6A_MOUSE	K(lysine) acetyltransferase 6A	KAT6A_HUMAN	Histone modification write	Histone acetylation	MOZ/MORF	H3 H4	H3ac H4ac
KAT6B	Linker_histone PF00538 106-175 MOZ_SAS PF01853 773-960 PHD PF00628 271-320 Pfam-B_6470 PB006470 1604-1717	KAT6B_MOUSE	K(lysine) acetyltransferase 6B	KAT6B_HUMAN	Histone modification write	Histone acetylation	MOZ/MORF	H3	H3ac
KAT7	MOZ_SAS PF01853 390-577 zf-C2HC PF01530 182-212	KAT7_MOUSE	K(lysine) acetyltransferase 7	KAT7_HUMAN	Histone modification write	Histone acetylation	HBO1	H4	H4ac
KAT8	MOZ_SAS PF01853 232-418 Tudor-knot PF11717 55-111	KAT8_MOUSE	K(lysine) acetyltransferase 8	KAT8_HUMAN	Histone modification write	Histone acetylation	NSL CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7	H2A H3 H4	H2Aac H3ac H4ac
KDM1A	Amino_oxidase PF01593 288-826 SWIRM PF04433 174-264	KDM1A_MOUSE	lysine (K)-specific demethylase 1A	KDM1A_HUMAN	Histone modification erase	Histone methylation	NuRD BHC SCL	H3K4me1 H3K4me2 H3K9me	H3K4 H3K9
KDM1B	Amino_oxidase PF01593 392-820 zf-CW PF07496 137-192	KDM1B_MOUSE	lysine (K)-specific demethylase 1B	KDM1B_HUMAN	Histone modification erase	Histone methylation	#	H3K4me1 H3K4me2	H3K4
KDM2A	F-box PF00646 889-935 JmjC PF02373 199-299 Pfam-B_11167 PB011167 362-470 Pfam-B_6618 PB006618 951-1149 Pfam-B_9841 PB009841 686-744 zf-CXXC PF02008 563-609	KDM2A_MOUSE	lysine (K)-specific demethylase 2A	KDM2A_HUMAN	Histone modification erase	Histone methylation	#	H3K36me2	H3K36
KDM2B	Cupin_8 PF13621 23-335 F-box PF00646 1050-1107 Pfam-B_23456 PB023456 441-519 Pfam-B_33113 PB033113 1235-1289 zf-CXXC PF02008 605-651	KDM2B_MOUSE	lysine (K)-specific demethylase 2B	KDM2B_HUMAN	Histone modification erase	Histone methylation	BCOR	H3K4me3 H3K36me2	H3K4 H3K36
KDM3A	JmjC PF02373 1151-1264 Pfam-B_14772 PB014772 851-889 Pfam-B_17027 PB017027 351-439 Pfam-B_6147 PB006147 441-539 Pfam-B_7111 PB007111 781-849	KDM3A_MOUSE	lysine (K)-specific demethylase 3A	KDM3A_HUMAN	Histone modification erase	Histone methylation	#	H3K9me1 H3K9me2	H3K9
KDM3B	JmjC PF02373 1594-1704 Pfam-B_16202 PB016202 1548-1593 Pfam-B_16670 PB016670 1497-1546 Pfam-B_19299 PB019299 351-469 Pfam-B_22020 PB022020 711-779 Pfam-B_3525 PB003525 571-639 Pfam-B_38652 PB038652 1-39 Pfam-B_6147 PB006147 471-569 Pfam-B_7111 PB007111 781-839	KDM3B_MOUSE	lysine (K)-specific demethylase 3B	KDM3B_HUMAN	Histone modification erase	Histone methylation	#	H3K9me1 H3K9me2	H3K9
KDM4A	JmjC PF02373 175-291 JmjN PF02375 15-49 PHD_2 PF13831 732-767 zf-HC5HC2H_2 PF13832 773-884	KDM4A_MOUSE	lysine (K)-specific demethylase 4A	KDM4A_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3 H3K36me3	H3K4me2 H3K36me2
KDM4B	JmjC PF02373 176-292 JmjN PF02375 16-50 PHD_2 PF13831 754-789 Pfam-B_12059 PB012059 1021-1094 zf-HC5HC2H_2 PF13832 795-906	KDM4B_MOUSE	lysine (K)-specific demethylase 4B	KDM4B_HUMAN	Histone modification erase	Histone methylation	#	H3K9me3	H3K9me1 H3K9me2
KDM4C	JmjC PF02373 177-293 JmjN PF02375 17-51 PHD_2 PF13831 712-747 Pfam-B_10616 PB010616 1021-1054 Pfam-B_14467 PB014467 422-670 Pfam-B_5109 PB005109 891-1019 zf-HC5HC2H_2 PF13832 753-864	KDM4C_MOUSE	lysine (K)-specific demethylase 4C	KDM4C_HUMAN	Histone modification erase	Histone methylation	#	H3K9me3 H3K36me3	H3K9me1 H3K9me2
KDM4D	JmjC PF02373 179-295 JmjN PF02375 19-53 Pfam-B_45485 PB045485 324-356 Pfam-B_84013 PB084013 451-521	KDM4D_MOUSE	lysine (K)-specific demethylase 4D	KDM4D_HUMAN	Histone modification erase	Histone methylation	#	H3K9me3	H3K9me1 H3K9me2
KDM4E	JmjC PF02373 176-292 JmjN PF02375 16-50	#	lysine (K)-specific demethylase 4E	KDM4E_HUMAN	Histone modification erase	Histone methylation	#	H3K9me2 H3K9me3	H3K9
KDM5A	ARID PF01388 81-170 JmjC PF02373 470-586 JmjN PF02375 20-53 PHD PF00628 295-343 1163-1218 PLU-1 PF08429 740-1072 zf-C5HC2 PF02928 676-729	KDM5A_MOUSE	lysine (K)-specific demethylase 5A	KDM5A_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3	H3K4
KDM5B	ARID PF01388 94-183 JmjC PF02373 486-602 JmjN PF02375 33-66 PHD PF00628 311-359 1178-1224 1486-1538 PLU-1 PF08429 756-1088 zf-C5HC2 PF02928 692-745	KDM5B_MOUSE	lysine (K)-specific demethylase 5B	KDM5B_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3	H3K4
KDM5C	ARID PF01388 76-165 JmjC PF02373 501-617 JmjN PF02375 15-48 PHD PF00628 326-374 1187-1250 PLU-1 PF08429 771-1100 Pfam-B_12821 PB012821 1417-1482 zf-C5HC2 PF02928 707-760	KDM5C_MOUSE	lysine (K)-specific demethylase 5C	KDM5C_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3	H3K4me2 H3K4me1
KDM5D	ARID PF01388 76-165 JmjC PF02373 491-607 JmjN PF02375 15-48 PHD PF00628 316-364 1174-1237 PLU-1 PF08429 761-1087 Pfam-B_12821 PB012821 1401-1443 zf-C5HC2 PF02928 697-750	KDM5D_MOUSE	lysine (K)-specific demethylase 5D	KDM5D_HUMAN	Histone modification erase	Histone methylation	#	H3K4me3 H3K4me2	H3K4
KDM6A	JmjC PF02373 1133-1241 Pfam-B_604 PB000604 631-769 Pfam-B_972 PB000972 771-1109 TPR_1 PF00515 130-163 318-351 352-380 TPR_17 PF13431 272-304 TPR_8 PF13181 205-238	KDM6A_MOUSE	lysine (K)-specific demethylase 6A	KDM6A_HUMAN	Histone modification erase	Histone methylation	CHD8 MLL2/3 MLL4/WBP7 COMPASS-like MLL3 4	H3K27me2. H3K27me3	H3K27
KDM6B	JmjC PF02373 1377-1485 Pfam-B_5108 PB005108 101-843 Pfam-B_992 PB000992 1-99	KDM6B_MOUSE	lysine (K)-specific demethylase 6B	KDM6B_HUMAN	Histone modification erase	Histone methylation	#	H3K27me2. H3K27me4	H3K28
KDM7A	PHD PF00628 39-88 JmjC PF02373 269-369 Pfam-B_18122 PB018122 381-538 Pfam-B_13686 PB013686 541-639 Pfam-B_1060 PB001060 853-939	KDM7A_MOUSE	lysine (K)-specific demethylase 7A	KDM7A_HUMAN	Histone modification erase	Histone methylation	#	H3K9me2 H3K27me2 H4K20me1	H3K9 H3K27 H4K20
KDM8	Cupin_8 PF13621 192-416	KDM8_MOUSE	lysine (K)-specific demethylase 8	KDM8_HUMAN	Histone modification erase	Histone methylation	#	H3K36me2	H3K36
KEAP1	BACK PF07707 184-286 BTB PF00651 67-179 Kelch_1 PF01344 317-359 361-410 412-457 459-504 506-551 553-598	KEAP1_MOUSE	kelch-like ECH-associated protein 1	KEAP1_HUMAN	Chromatin remodelling	#	#	#	#
KMT2A	FYRC PF05965 3666-3749 FYRN PF05964 2023-2073 PHD PF00628 1481-1533 1568-1627 Pfam-B_11202 PB011202 1021-1086 SET PF00856 3840-3945 zf-CXXC PF02008 1147-1194 zf-HC5HC2H PF13771 1900-1978	KMT2A_MOUSE	lysine (K)-specific methyltransferase 2A	KMT2A_HUMAN	Histone modification write	Histone methylation	MLL-HCF CHD8 COMPASS-like MLL1 2	H3K4	H3K4me
KMT2B	FYRC PF05965 2411-2494 FYRN PF05964 1732-1782 PHD PF00628 1251-1303 1337-1396 Pfam-B_25060 PB025060 1783-1849 Pfam-B_25524 PB025524 1168-1202 Pfam-B_26440 PB026440 701-839 Pfam-B_27348 PB027348 2191-2289 Pfam-B_3353 PB003353 1981-2079 Pfam-B_6332 PB006332 1401-1479 Pfam-B_85509 PB085509 345-387 SET PF00856 2586-2691 zf-CXXC PF02008 958-1005 zf-HC5HC2H PF13771 1608-1686	KMT2B_MOUSE	lysine (K)-specific methyltransferase 2B	KMT2B_HUMAN	Histone modification write	Histone methylation	Menin-associated_HMT MLL2/3 COMPASS-like MLL3 4	H3K4	H3K4me3
KMT2C	FYRC PF05965 4606-4693 FYRN PF05964 4550-4604 PHD PF00628 390-438 959-1010 1009-1060 Pfam-B_16694 PB016694 2536-2572 Pfam-B_19991 PB019991 1874-1906 Pfam-B_43 PB000043 3044-3095 Pfam-B_49476 PB049476 1-159 SET PF00856 4782-4887 zf-HC5HC2H PF13771 252-331 4429-4507	KMT2C_MOUSE	lysine (K)-specific methyltransferase 2C	KMT2C_HUMAN	Histone modification write	Histone methylation	MLL2/3 COMPASS-like MLL3 4	H3K4	H3K4me
KMT2D	FYRC PF05965 5236-5323 FYRN PF05964 5180-5234 PHD PF00628 275-323 1379-1429 1429-1477 Pfam-B_26489 PB026489 5016-5050 Pfam-B_29065 PB029065 423-678 Pfam-B_2976 PB002976 1682-1717 Pfam-B_33020 PB033020 3681-3767 SET PF00856 5408-5513 zf-HC5HC2H PF13771 139-218 5059-5137	KMT2D_MOUSE	lysine (K)-specific methyltransferase 2D	KMT2D_HUMAN	Histone modification write	Histone methylation	COMPASS-like MLL1 2 MLL4/WBP7 COMPASS-like MLL3 4	H3K4	H3K4me
KMT2E	PHD PF00628 120-166 Pfam-B_13611 PB013611 1791-1856 Pfam-B_19470 PB019470 1301-1369 Pfam-B_19601 PB019601 1131-1179 Pfam-B_20626 PB020626 961-1129 Pfam-B_22469 PB022469 871-959 Pfam-B_24586 PB024586 1261-1299 Pfam-B_7010 PB007010 1651-1789 Pfam-B_7713 PB007713 731-869 SET PF00856 342-447	KMT2E_MOUSE	lysine (K)-specific methyltransferase 2E	KMT2E_HUMAN	Histone modification write	Histone methylation	#	H3K4	H3K4me1 H3K4me2
L3MBTL1	MBT PF02820 242-314 349-421 453-525 SAM_1 PF00536 681-745 zf-C2HC PF01530 551-581	LMBL1_MOUSE	l(3)mbt-like 1 (Drosophila)	LMBL1_HUMAN	Histone modification read	#	L3MBTL1	H1BK26 H4K20	#
L3MBTL2	MBT PF02820 214-290 327-395 432-508 540-610	LMBL2_MOUSE	l(3)mbt-like 2 (Drosophila)	LMBL2_HUMAN	Histone modification read	#	RING2-L3MBTL2	H3K4 H3K9 H3K27 H4K20	#
L3MBTL3	MBT PF02820 268-340 375-447 479-548 Pfam-B_29190 PB029190 1-79 SAM_1 PF00536 706-770	LMBL3_MOUSE	l(3)mbt-like 3 (Drosophila)	LMBL3_HUMAN	Histone modification read	#	#	H4K20me	#
L3MBTL4	MBT PF02820 88-160 196-268 300-371 SAM_1 PF00536 541-605 zf-C2HC PF01530 376-407	LMBL4_MOUSE	l(3)mbt-like 4 (Drosophila)	LMBL4_HUMAN	Histone modification read	#	#	HKme	#
LAS1L	Las1 PF04031 42-188 Pfam-B_28535 PB028535 671-732	LAS1L_MOUSE	LAS1-like (S. cerevisiae)	LAS1L_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	H3K4 H3 H4 H2A	H3K4me H3K4me2 H3Ac H4Ac H2AAc
LBR	ERG4_ERG24 PF01222 183-615 LBR_tudor PF09465 1-55	LBR_MOUSE	lamin B receptor	LBR_HUMAN	#	#	#	#	#
LEO1	Leo1 PF04004 373-537 Pfam-B_17842 PB017842 1-105 Pfam-B_20153 PB020153 171-239 Pfam-B_6431 PB006431 241-309	LEO1_MOUSE	Leo1 Paf1/RNA polymerase II complex component homolog (S. cerevisiae)	LEO1_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	#	#
LRWD1	LRR_1 PF00560 48-69 Pfam-B_28625 PB028625 274-344 Pfam-B_39252 PB039252 191-239 WD40 PF00400 382-421	LRWD1_MOUSE	leucine-rich repeats and WD repeat domain containing 1	LRWD1_HUMAN	Chromatin remodelling	#	#	H3K9me3 H3K27me3	#
MAP3K7	Pfam-B_11880 PB011880 521-569 Pkinase_Tyr PF07714 36-284	M3K7_MOUSE	mitogen-activated protein kinase kinase kinase 7	M3K7_HUMAN	Histone modification write	#	#	#	#
MAPKAPK3	Pkinase PF00069 44-304	MAPK3_MOUSE	mitogen-activated protein kinase-activated protein kinase 3	MAPK3_HUMAN	Chromatin remodelling	#	#	#	#
MASTL	Pfam-B_24677 PB024677 271-369 Pfam-B_8409 PB008409 371-489 Pkinase PF00069 35-203 733-835	GWL_MOUSE	microtubule associated serine/threonine kinase-like	GWL_HUMAN	Histone modification write	Histone phosphorylation	#	H1 H3	H1p H3p
MAX	HLH PF00010 24-75	MAX_MOUSE	MYC associated factor X	MAX_HUMAN	Histone modification write cofactor Histone modification write cofactor TF TF	Histone methylation Histone acetylation TF activator TF repressor	CHD8 MLL2/3 MLL4/WBP7	DNA motif	#
MAZ	zf-C2H2 PF00096 337-360 zf-C2H2_4 PF13894 190-213 366-388 zf-H2C2_2 PF13465 293-318	MAZ_MOUSE	MYC-associated zinc finger protein (purine-binding transcription factor)	MAZ_HUMAN	Chromatin remodelling	#	#	#	#
MBD1	MBD PF01429 1-85 Pfam-B_12306 PB012306 468-526 Pfam-B_9691 PB009691 528-587 zf-CXXC PF02008 168-215 217-262 330-377	MBD1_MOUSE	methyl-CpG binding domain protein 1	MBD1_HUMAN	Histone modification write cofactor TF	Histone methylation TF repressor	#	mCG DNA motif	#
MBD2	MBD PF01429 145-216 MBD_C PF14048 294-387	MBD2_MOUSE	methyl-CpG binding domain protein 2	MBD2_HUMAN	Histone modification write cofactor Histone modification erase cofactor TF	Histone methylation Histone acetylation TF repressor	NuRD MeCP1	mCG DNA motif	#
MBD3	MBD PF01429 1-72 MBD_C PF14048 150-243	MBD3_MOUSE	methyl-CpG binding domain protein 3	MBD3_HUMAN	Histone modification erase cofactor	Histone acetylation	NuRD	#	#
MBD4	HhH-GPD PF00730 461-575 MBD PF01429 76-151 Pfam-B_47325 PB047325 409-460	MBD4_MOUSE	methyl-CpG binding domain protein 4	MBD4_HUMAN	DNA modification	#	#	G:T G:U	#
MBD5	Pfam-B_1400 PB001400 981-1140 Pfam-B_19258 PB019258 499-567 Pfam-B_41495 PB041495 438-497 Pfam-B_51737 PB051737 1-119 Pfam-B_5417 PB005417 121-219 Pfam-B_7705 PB007705 221-410	MBD5_MOUSE	methyl-CpG binding domain protein 5	MBD5_HUMAN	Chromatin remodelling	#	#	#	#
MBD6	Pfam-B_28044 PB028044 161-209	MBD6_MOUSE	methyl-CpG binding domain protein 6	MBD6_HUMAN	Chromatin remodelling	#	#	#	#
MBIP	Pfam-B_15854 PB015854 191-249 Pfam-B_276 PB000276 251-342	MBIP1_MOUSE	MAP3K12 binding inhibitory protein 1	MBIP1_HUMAN	Histone modification write cofactor	Histone acetylation	ATAC	#	#
MBTD1	MBT PF02820 183-253 289-360 388-464 496-568 Pfam-B_45320 PB045320 1-59	MBTD1_MOUSE	mbt domain containing 1	MBTD1_HUMAN	Polycomb group (PcG) protein	#	#	H4K20me1 H4K20me2	#
MCRS1	FHA PF00498 363-436 MCRS_N PF13325 134-331	MCRS1_MOUSE	microspherule protein 1	MCRS1_HUMAN	Histone modification write	Histone acetylation	Ino80 NSL CHD8 MLL2/3 MLL4/WBP7	H4K5 H4K8 H4K16	H4K5ac H4K8ac H4K16ac
MDC1	FHA PF00498 54-124 Pfam-B_1811 PB001811 319-407	MDC1_MOUSE	mediator of DNA-damage checkpoint 1	MDC1_HUMAN	Histone modification read	#	#	H2AX	#
MEAF6	NuA4 PF09340 16-97	EAF6_MOUSE	MYST/Esa1-associated factor 6	EAF6_HUMAN	Histone modification write cofactor	Histone acetylation	HBO1 NuA4 MOZ/MORF	H2A H3K14 H4K5 H4K8 H4K12	H2Aac H3K14ac H4K5ac H4K8ac H4K12ac
MECP2	MBD PF01429 90-164	MECP2_MOUSE	methyl CpG binding protein 2	MECP2_HUMAN	Histone modification write cofactor Histone modification write cofactor TF	Histone methylation Histone acetylation TF repressor	#	mCG DNA motif	#
MEN1	Menin PF05053 1-615	MEN1_MOUSE	multiple endocrine neoplasia I	MEN1_HUMAN	Histone modification write cofactor	Histone methylation	Menin-associated_HMT MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7	H3K4	H3K4me
MGA	HLH PF00010 2385-2436 Pfam-B_11518 PB011518 378-497 Pfam-B_24878 PB024878 2971-3008 Pfam-B_591 PB000591 979-1080 1332-1376 Pfam-B_7320 PB007320 1791-1938 Pfam-B_80122 PB080122 1-39 Pfam-B_8542 PB008542 653-837 T-box PF00907 76-261	MGAP_MOUSE	MGA MAX dimerization protein	MGAP_HUMAN	Histone modification write cofactor Histone modification write cofactor TF TF	Histone methylation Histone acetylation TF activator TF repressor	RING2-L3MBTL2 CHD8 MLL2/3 MLL4/WBP7	DNA motif	#
MGEA5	NAGidase PF07555 62-364 Pfam-B_15148 PB015148 851-895	NCOAT_MOUSE	meningioma expressed antigen 5 (hyaluronidase)	NCOAT_HUMAN	Histone modification write	Histone acetylation	#	H3K14 H4K8	H3K14ac H4K8ac
MINA	Cupin_4 PF08007 51-364	MINA_MOUSE	MYC induced nuclear antigen	MINA_HUMAN	Histone modification erase	Histone methylation	#	H3K9me3	H3K9
MLLT1	YEATS PF03366 29-112	#	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 1	ENL_HUMAN	Chromatin remodelling cofactor	#	SWI/SNF-like_EPAFa SWI/SNF-like EPAFB	#	#
MLLT6	Pfam-B_16181 PB016181 791-1091 Pfam-B_3448 PB003448 551-789 zf-HC5HC2H_2 PF13832 63-180	#	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 6	AF17_HUMAN	Histone modification write cofactor	Histone methylation	#	H3K79	H3K79me3
MLLT10	PHD_2 PF13831 36-72 Pfam-B_12689 PB012689 541-619 Pfam-B_12729 PB012729 821-879 Pfam-B_4074 PB004074 234-538 Pfam-B_6933 PB006933 721-819 Pfam-B_9291 PB009291 621-719 zf-HC5HC2H_2 PF13832 80-197	AF10_MOUSE	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog Drosophila); translocated to 10	AF10_HUMAN	Histone modification write cofactor	Histone methylation	#	H3K79	H3K79me3
MORF4L1	MRG PF05712 166-350 Tudor-knot PF11717 11-53	MO4L1_MOUSE	mortality factor 4 like 1	MO4L1_HUMAN	Histone modification read	#	NuA4	H4	#
MORF4L2	MRG PF05712 93-276 Pfam-B_26706 PB026706 1-39	MO4L2_MOUSE	mortality factor 4 like 2	MO4L2_HUMAN	Histone modification erase cofactor	Histone acetylation	NuA4	#	#
MOV10	AAA_11 PF13086 498-605 599-691 AAA_12 PF13087 698-923 Pfam-B_18178 PB018178 1-114	MOV10_MOUSE	Mov10 RISC complex RNA helicase	MOV10_HUMAN	#	#	#	#	#
MPHOSPH8	Ank_2 PF12796 570-664 647-730 Chromo PF00385 59-109	MPP8_MOUSE	M-phase phosphoprotein 8	MPP8_HUMAN	Histone modification read	#	#	H3K9me3 H3K9me2	#
MRGBP	Eaf7 PF07904 34-114	MRGBP_MOUSE	MRG/MORF4L binding protein	MRGBP_HUMAN	Histone modification write cofactor	Histone acetylation	NuA4	#	#
MSH6	MutS_I PF01624 407-526 MutS_II PF05188 537-703 MutS_III PF05192 737-1065 MutS_IV PF05190 932-1024 MutS_V PF00488 1074-1326 PWWP PF00855 90-182	MSH6_MOUSE	mutS homolog 6	MSH6_HUMAN	Histone modification read	#	#	H3K36me3	#
MSL1	PEHE PF15275 473-591 Pfam-B_41610 PB041610 41-129 Pfam-B_70275 PB070275 1-39	MSL1_MOUSE	male-specific lethal 1 homolog (Drosophila)	MSL1_HUMAN	Histone modification write	Histone ubiquitination	#	H2BK34	H2BK34ub
MSL2	Pfam-B_16851 PB016851 461-575 Pfam-B_19348 PB019348 1-89 Pfam-B_20099 PB020099 211-459 Pfam-B_22844 PB022844 91-209	MSL2_MOUSE	male-specific lethal 2 homolog (Drosophila)	MSL2_HUMAN	Histone modification write	Histone ubiquitination	#	H2BK34	H2BK34ub
MSL3	MRG PF05712 136-504 Tudor-knot PF11717 11-74	MS3L1_MOUSE	male-specific lethal 3 homolog (Drosophila)	MS3L1_HUMAN	Histone modification read	#	#	H4K20me1	#
MST1	Kringle PF00051 110-186 191-268 283-361 370-448 PAN_1 PF00024 16-106 Trypsin PF00089 484-704	HGFL_MOUSE	macrophage stimulating 1 (hepatocyte growth factor-like)	HGFL_HUMAN	Histone modification	#	#	#	#
MTA1	BAH PF01426 4-164 ELM2 PF01448 167-221 GATA PF00320 393-430	MTA1_MOUSE	metastasis associated 1	MTA1_HUMAN	Chromatin remodelling cofactor	#	NuRD	#	#
MTA2	BAH PF01426 4-144 ELM2 PF01448 147-201 GATA PF00320 367-404 Pfam-B_3593 PB003593 571-637	MTA2_MOUSE	metastasis associated 1 family member 2	MTA2_HUMAN	Histone modification erase cofactor	Histone acetylation	NuRD	#	#
MTA3	BAH PF01426 4-147 ELM2 PF01448 150-204 GATA PF00320 379-416 Pfam-B_11869 PB011869 421-489 Pfam-B_22870 PB022870 491-520	MTA3_MOUSE	metastasis associated 1 family member 3	MTA3_HUMAN	Chromatin remodelling cofactor	#	NuRD	#	#
MTF2	Mtf2_C PF14061 542-592 PHD PF00628 104-157	MTF2_MOUSE	metal response element binding transcription factor 2	MTF2_HUMAN	Polycomb group (PcG) protein	#	PRC2	H3K36me3	#
MUM1	Pfam-B_7774 PB007774 1-232	MUM1_MOUSE	melanoma associated antigen (mutated) 1	MUM1_HUMAN	Histone modification read	#	#	H3K36me K3K79me H4K20me	#
MYBBP1A	DNA_pol_phi PF04931 70-836	MBB1A_MOUSE	MYB binding protein (P160) 1a	MBB1A_HUMAN	Chromatin remodelling cofactor	#	B-WICH	#	#
MYO1C	IQ PF00612 735-755 758-777 Myosin_TH1 PF06017 873-1059 Myosin_head PF00063 48-718	MYO1C_MOUSE	myosin IC	MYO1C_HUMAN	Chromatin remodelling cofactor	#	B-WICH	#	#
MYSM1	JAB PF01398 572-682 Myb_DNA-binding PF00249 118-163 Pfam-B_30622 PB030622 691-736 SWIRM PF04433 372-461	MYSM1_MOUSE	Myb-like SWIRM and MPN domains 1	MYSM1_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Aub	H2A
NAA60	Acetyltransf_1 PF00583 57-156	NAA60_MOUSE	N(alpha)-acetyltransferase 60 NatF catalytic subunit	NAA60_HUMAN	Histone modification write	Histone acetylation	#	H4K20 H4K79 H4K91	H4K20ac H4K79ac H4K91ac
NAP1L1	NAP PF00956 75-346	NP1L1_MOUSE	nucleosome assembly protein 1-like 1	NP1L1_HUMAN	Histone chaperone	#	#	#	#
NAP1L2	NAP PF00956 109-412	NP1L2_MOUSE	nucleosome assembly protein 1-like 2	NP1L2_HUMAN	Histone modification cofactor	#	#	H3 H4	#
NAP1L4	NAP PF00956 64-339	NP1L4_MOUSE	nucleosome assembly protein 1-like 4	NP1L4_HUMAN	Histone modification cofactor	#	#	H3 H4	#
NASP	SHNi-TPR PF10516 542-579 TPR_1 PF00515 584-617	NASP_MOUSE	nuclear autoantigenic sperm protein (histone-binding)	NASP_HUMAN	Chromatin remodelling	#	#	H1	#
NAT10	DUF1726 PF08351 107-201 GNAT_acetyltr_2 PF13718 528-753 Helicase_RecD PF05127 281-488 tRNA_bind_2 PF13725 771-892	NAT10_MOUSE	N-acetyltransferase 10 (GCN5-related)	NAT10_HUMAN	Histone modification write	Histone acetylation	#	#	#
NBN	FHA PF00498 24-100 Nbs1_C PF08599 682-746	NBN_MOUSE	nibrin	NBN_HUMAN	Chromatin remodelling	#	#	H2AX	#
NCL	Pfam-B_12581 PB012581 1-59 RRM_1 PF00076 309-377 395-460 488-554 574-641	NUCL_MOUSE	nucleolin	NUCL_HUMAN	Histone chaperone	#	#	DNA motif RNA motif	#
NCOA1	DUF1518 PF07469 1149-1205 1212-1268 Nuc_rec_co-act PF08815 924-973 PAS PF00989 112-183 PAS_11 PF14598 259-370 SRC-1 PF08832 625-708	NCOA1_MOUSE	nuclear receptor coactivator 1	NCOA1_HUMAN	Histone modification write	Histone acetylation	#	H3 H4	#
NCOA2	DUF1518 PF07469 1281-1338 Nuc_rec_co-act PF08815 1071-1117 PAS PF00989 115-215 PAS_11 PF14598 267-379 SRC-1 PF08832 636-709	NCOA2_MOUSE	nuclear receptor coactivator 2	NCOA2_HUMAN	Chromatin remodelling cofactor	#	#	#	#
NCOA3	DUF1518 PF07469 1291-1348 Nuc_rec_co-act PF08815 1045-1095 PAS PF00989 113-210 PAS_11 PF14598 264-375 Pfam-B_10879 PB010879 1096-1195 Pfam-B_14009 PB014009 794-924 SRC-1 PF08832 616-704	NCOA3_MOUSE	nuclear receptor coactivator 3	NCOA3_HUMAN	Histone modification write	Histone acetylation	#	#	#
NCOA6	Nucleic_acid_bd PF13820 45-195 Pfam-B_14375 PB014375 987-1511 Pfam-B_3537 PB003537 407-669	NCOA6_MOUSE	nuclear receptor coactivator 6	NCOA6_HUMAN	Histone modification write cofactor	Histone methylation	CHD8 MLL2/3 COMPASS-like MLL3 4	#	#
NCOR1	Myb_DNA-binding PF00249 625-670 Pfam-B_4054 PB004054 1242-1723 Pfam-B_670 PB000670 1725-1983 Pfam-B_7837 PB007837 1-159	NCOR1_MOUSE	nuclear receptor corepressor 1	NCOR1_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
NCOR2	Myb_DNA-binding PF00249 612-657 Pfam-B_1539 PB001539 271-430	NCOR2_MOUSE	nuclear receptor corepressor 2	NCOR2_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
NEK6	Pkinase PF00069 45-306	NEK6_MOUSE	NIMA-related kinase 6	NEK6_HUMAN	Histone modification write	Histone phosphorylation	#	H1 H3	H1ph H3ph
NEK9	Pfam-B_22064 PB022064 309-349 Pkinase PF00069 52-308 RCC1 PF00415 390-441 444-495 499-547 615-665	NEK9_MOUSE	NIMA-related kinase 9	NEK9_HUMAN	Histone modification write	Histone phosphorylation	#	H1	H1ph
NFRKB	NFRKB_winged PF14465 379-478 Pfam-B_18306 PB018306 610-661	NFRKB_MOUSE	nuclear factor related to kappaB binding protein	NFRKB_HUMAN	Chromatin remodelling cofactor TF	# #	Ino80	DNA motif	#
NFYB	CBFD_NFYB_HMF PF00808 57-122 Pfam-B_17851 PB017851 1-39	NFYB_MOUSE	nuclear transcription factor Y beta	NFYB_HUMAN	Chromatin remodelling TF	# TF activator	#	DNA motif	#
NFYC	CBFD_NFYB_HMF PF00808 41-105 Pfam-B_8767 PB008767 141-201	NFYC_MOUSE	nuclear transcription factor Y gamma	NFYC_HUMAN	Histone modification	#	#	#	#
NIPBL	Cohesin_HEAT PF12765 1794-1835 Nipped-B_C PF12830 2274-2457 Pfam-B_338 PB000338 1292-1355 Pfam-B_4450 PB004450 1859-2018 Pfam-B_5032 PB005032 2020-2194	NIPBL_MOUSE	Nipped-B homolog (Drosophila)	NIPBL_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
NOC2L	Noc2 PF03715 325-623 Pfam-B_22168 PB022168 62-101 Pfam-B_2429 PB002429 644-713 Pfam-B_50064 PB050064 1-31	NOC2L_MOUSE	nucleolar complex associated 2 homolog (S. cerevisiae)	NOC2L_HUMAN	Chromatin remodelling TF	# TF repressor	#	H3	#
NPAS2	HLH PF00010 10-59 PAS PF00989 84-176 PAS_11 PF14598 248-356	NPAS2_MOUSE	neuronal PAS domain protein 2	NPAS2_HUMAN	Chromatin remodelling TF	# TF activator	#	DNA motif	#
NPM1	Nucleoplasmin PF03066 13-196	NPM_MOUSE	nucleophosmin (nucleolar phosphoprotein B23 numatrin)	NPM_HUMAN	Histone chaperone	#	#	H3 H2B H4	#
NPM2	TSP_1 PF00090 161-209 213-267 271-316 319-374	NPM2_MOUSE	nucleophosmin/nucleoplasmin 2	NPM2_HUMAN	Histone chaperone	#	#	H2A H2B	#
NSD1	PHD PF00628 1709-1751 PWWP PF00855 321-419 1754-1844 Pfam-B_7228 PB007228 821-937 SET PF00856 1953-2059	NSD1_MOUSE	nuclear receptor binding SET domain protein 1	NSD1_HUMAN	Histone modification write	Histone methylation	#	H3K36 H4K20	H3K36me H4K20me
NSL1	Mis14 PF08641 67-211	NSL1_MOUSE	NSL1 MIS12 kinetochore complex component	NSL1_HUMAN	Histone modification write cofactor	Histone acetylation	#	H4K16	H4K16ac
OGT	Glyco_transf_41 PF13844 556-1024 TPR_1 PF00515 89-122 191-224 225-258 259-292 293-326 327-360 361-394 395-428 429-462 TPR_11 PF13414 87-154 TPR_8 PF13181 160-190	OGT1_MOUSE	O-linked N-acetylglucosamine (GlcNAc) transferase	OGT1_HUMAN	Histone modification write	Histone GlcNAcylation	NSL	H2BS112	H2BS112GlcNa
PADI1	PAD PF03068 276-663 PAD_M PF08527 115-273 PAD_N PF08526 1-113	PADI1_MOUSE	peptidyl arginine deiminase type I	PADI1_HUMAN	Histone modification	Histone citrullination	#	H2AR H3R H4R	H2ARci H3Rci H4Rci
PADI2	PAD PF03068 279-665 PAD_M PF08527 116-274 PAD_N PF08526 1-114	PADI2_MOUSE	peptidyl arginine deiminase type II	PADI2_HUMAN	Histone modification	Histone citrullination	#	H2AR H3R H4R	H2ARci H3Rci H4Rci
PADI3	PAD PF03068 278-664 PAD_M PF08527 115-273 PAD_N PF08526 1-113	PADI3_MOUSE	peptidyl arginine deiminase type III	PADI3_HUMAN	Histone modification	Histone citrullination	#	H2AR H3R H4R	H2ARci H3Rci H4Rci
PADI4	PAD PF03068 278-663 PAD_M PF08527 113-273 PAD_N PF08526 1-111	PADI4_MOUSE	peptidyl arginine deiminase type IV	PADI4_HUMAN	Histone modification	Histone citrullination	#	H2AR H3R2 H3R8 H3R17 H3R26 H4R	H2ARci H3R2ci H3R8ci H3R17ci H3R26ci H4Rci
PAF1	Paf1 PF03985 27-446	PAF1_MOUSE	Paf1 RNA polymerase II associated factor homolog (S. cerevisiae)	PAF1_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	H2 H3	#
PAGR1	PAXIP1_C PF15364 86-221	PAGR1_MOUSE	PAXIP1 associated glutamate-rich protein 1	PAGR1_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7 COMPASS-like MLL3 4	#	#
PAK2	PBD PF00786 73-131 Pkinase PF00069 249-500	PAK2_MOUSE	p21 protein (Cdc42/Rac)-activated kinase 2	PAK2_HUMAN	Histone modification write	Histone phosphorylation	#	H4S47	H4S47ph
PARG	PARG_cat PF05028 577-912 Pfam-B_14007 PB014007 925-955	PARG_MOUSE	poly (ADP-ribose) glycohydrolase	PARG_HUMAN	Chromatin remodelling	#	#	H3K9	#
PARP1	BRCT PF00533 385-462 PADR1 PF08063 279-332 PARP PF00644 797-1007 PARP_reg PF02877 662-795 WGR PF05406 549-633 zf-PARP PF00645 12-90 116-200	PARP1_MOUSE	poly (ADP-ribose) polymerase 1	PARP1_HUMAN	Chromatin remodelling	#	#	H1	#
PARP2	PARP PF00644 365-577 PARP_reg PF02877 231-363 WGR PF05406 111-195	PARP2_MOUSE	poly (ADP-ribose) polymerase 2	PARP2_HUMAN	Chromatin remodelling cofactor	#	#	#	#
PARP3	PARP PF00644 322-533 PARP_reg PF02877 182-320 WGR PF05406 62-144	#	poly (ADP-ribose) polymerase family member 3	PARP3_HUMAN	Polycomb group (PcG) protein	#	#	#	#
PAXIP1	BRCT PF00533 601-681 701-776 867-934 PTCB-BRCT PF12738 102-165 Pfam-B_13490 PB013490 1009-1064 Pfam-B_16838 PB016838 485-548	PAXI1_MOUSE	PAX interacting (with transcription-activation domain) protein 1	PAXI1_HUMAN	Histone modification write cofactor	Histone methylation	CHD8 MLL2/3 MLL4/WBP7 COMPASS-like MLL3 4	H3K4	H3K4me3
PBK	Pkinase PF00069 33-318	TOPK_MOUSE	PDZ binding kinase	TOPK_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10	H3S10ph
PBRM1	BAH PF01426 956-1074 1156-1272 Bromodomain PF00439 54-139 186-275 392-475 532-613 666-750 785-867 HMG_box PF00505 1379-1446	PB1_MOUSE	polybromo 1	PB1_HUMAN	Histone modification read	#	PBAF SWI/SNF BRM-BRG1	H3	#
PCGF1	zf-C3HC4 PF00097 47-85	PCGF1_MOUSE	polycomb group ring finger 1	PCGF1_HUMAN	Polycomb group (PcG) protein	#	PRC1 BCOR	#	#
PCGF2	zf-C3HC4 PF00097 18-56	PCGF2_MOUSE	polycomb group ring finger 2	PCGF2_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
PCGF3	zf-C3HC4 PF00097 17-55	PCGF3_MOUSE	polycomb group ring finger 3	PCGF3_HUMAN	Polycomb group (PcG) protein	#	PRC1 RING2-FBRS	#	#
PCGF5	zf-C3HC4 PF00097 18-56	PCGF5_MOUSE	polycomb group ring finger 5	PCGF5_HUMAN	Polycomb group (PcG) protein	#	PRC1 RING2-FBRS	#	#
PCGF6	zf-C3HC4 PF00097 134-172	PCGF6_MOUSE	polycomb group ring finger 6	PCGF6_HUMAN	Polycomb group (PcG) protein	#	PRC1 RING2-L3MBTL2	#	#
PCNA	PCNA_C PF02747 127-254 PCNA_N PF00705 1-125	PCNA_MOUSE	proliferating cell nuclear antigen	PCNA_HUMAN	Chromatin remodelling	#	#	H2A H2B	#
PDP1	PP2C PF00481 194-487 Pfam-B_13776 PB013776 99-163	PDP1_MOUSE	pyruvate dehyrogenase phosphatase catalytic subunit 1	PDP1_HUMAN	Histone modification read	#	#	H4K20me3	#
PELP1	NUC202 PF08166 423-489 569-642 RIX1 PF08167 66-226	PELP1_MOUSE	proline glutamate and leucine rich protein 1	PELP1_HUMAN	Histone modification read Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	H1 H3 H4	#
PHC1	Pfam-B_4954 PB004954 615-678 Pfam-B_5821 PB005821 430-536 SAM_1 PF00536 938-1002 zf-FCS PF06467 792-827	PHC1_MOUSE	polyhomeotic homolog 1 (Drosophila)	PHC1_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
PHC2	Pfam-B_5669 PB005669 651-679 Pfam-B_6832 PB006832 1-198 SAM_1 PF00536 792-856	PHC2_MOUSE	polyhomeotic homolog 2 (Drosophila)	PHC2_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
PHC3	Pfam-B_12208 PB012208 689-724 Pfam-B_17091 PB017091 431-487 Pfam-B_19383 PB019383 780-822 Pfam-B_19396 PB019396 1-39 SAM_1 PF00536 917-981	PHC3_MOUSE	polyhomeotic homolog 3 (Drosophila)	PHC3_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
PHF1	Mtf2_C PF14061 525-566 PHD PF00628 89-142 Pfam-B_18040 PB018040 1-30 Pfam-B_24844 PB024844 331-384	PHF1_MOUSE	PHD finger protein 1	PHF1_HUMAN	Polycomb group (PcG) protein	#	PRC2	#	#
PHF2	JmjC PF02373 236-336 PHD PF00628 7-56 Pfam-B_3847 PB003847 851-988	PHF2_MOUSE	PHD finger protein 2	PHF2_HUMAN	Histone modification erase	Histone methylation	#	H3K9me2	H3K9
PHF8	JmjC PF02373 270-370 PHD PF00628 43-92 Pfam-B_22520 PB022520 499-557 Pfam-B_5629 PB005629 779-877	PHF8_MOUSE	PHD finger protein 8	PHF8_HUMAN	Histone modification erase	Histone methylation	#	H3K9me1 H3K9me2 H3K27me2 H4K20me1 H3K36me2 H3K36me3 H3K4me3	H3K9 H3K27 H4K20 H3K36 H3K4
PHF10	PHD PF00628 379-436 435-481 Pfam-B_1316 PB001316 15-230	PHF10_MOUSE	PHD finger protein 10	PHF10_HUMAN	Chromatin remodelling	#	npBAF SWI/SNF BRM-BRG1	#	#
PHF12	PHD PF00628 58-105 273-318	PHF12_MOUSE	PHD finger protein 12	PHF12_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
PHF13	PHD PF00628 234-280 Pfam-B_28476 PB028476 1-49	PHF13_MOUSE	PHD finger protein 13	PHF13_HUMAN	Histone modification read	#	#	H3K4me3	#
PHF14	PHD PF00628 321-380 727-779 Pfam-B_16803 PB016803 175-216 Pfam-B_19012 PB019012 218-295 zf-HC5HC2H_2 PF13832 383-498	PHF14_MOUSE	PHD finger protein 14	PHF14_HUMAN	Histone modification read	#	#	H2A H2B H3	H2Aac H2Bac H3ac
PHF19	Mtf2_C PF14061 529-579 PHD PF00628 98-151 Pfam-B_31053 PB031053 1-59	PHF19_MOUSE	PHD finger protein 19	PHF19_HUMAN	Chromatin remodelling Histone modification write cofactor	# Histone acetylation	PRC2	#	#
PHF20	DUF3776 PF12618 173-279 PHD PF00628 654-700 Pfam-B_21846 PB021846 511-589 Pfam-B_23453 PB023453 280-309	PHF20_MOUSE	PHD finger protein 20	PHF20_HUMAN	Histone modification write	Histone acetylation	NSL CHD8 MLL2/3 MLL4/WBP7	H4	H4ac
PHF20L1	DUF3776 PF12618 210-317 415-518 PHD PF00628 683-729 Pfam-B_37699 PB037699 791-849	P20L1_MOUSE	PHD finger protein 20-like 1	P20L1_HUMAN	Histone modification read	#	#	H3K4me	#
PHF21A	AT_hook PF02178 425-436 PHD PF00628 490-535 Pfam-B_15568 PB015568 536-649 Pfam-B_7050 PB007050 1-349	PF21A_MOUSE	PHD finger protein 21A	PF21A_HUMAN	Histone modification erase cofactor	Histone methylation	BHC LSD-CoREST	#	#
PHIP	Bromodomain PF00439 1165-1251 1325-1409 Pfam-B_15784 PB015784 743-864 Pfam-B_60538 PB060538 1-77 WD40 PF00400 174-211 215-253 257-298 355-393 456-495	PHIP_MOUSE	pleckstrin homology domain interacting protein	PHIP_HUMAN	Histone modification read	#	#	H3	#
PIWIL4	PAZ PF02170 271-407 Pfam-B_2782 PB002782 101-219 Pfam-B_34294 PB034294 1-99 Piwi PF02171 546-838	PIWL4_MOUSE	piwi-like RNA-mediated gene silencing 4	PIWL4_HUMAN	Chromatin remodelling Histone modification erase cofactor	# Histone methylation	#	H3K9	#
PKM	PK PF00224 42-395 PK_C PF02887 409-529	KPYM_MOUSE	pyruvate kinase muscle	KPYM_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	H3S10 H3S28 H2BS32	H3S10ph H3S28ph H2BS32ph H3T11ph
PKN1	HR1 PF02185 37-105 126-198 213-285 Pfam-B_33979 PB033979 8-36 Pkinase PF00069 615-874 Pkinase_C PF00433 894-940	PKN1_MOUSE	protein kinase N1	PKN1_HUMAN	Histone modification write	Histone phosphorylation	#	H3T11	H3T11ph
POGZ	DDE_1 PF03184 1117-1304 HTH_Tnp_Tc5 PF03221 1024-1085 Pfam-B_10413 PB010413 693-771 Pfam-B_10981 PB010981 1-69 Pfam-B_5179 PB005179 796-843 Pfam-B_6754 PB006754 773-795	POGZ_MOUSE	pogo transposable element with ZNF domain	POGZ_HUMAN	Histone modification read	Histone methylation	#	H3K9me3	#
POLE3	CBFD_NFYB_HMF PF00808 8-73 Pfam-B_35841 PB035841 74-135	DPOE3_MOUSE	polymerase (DNA directed) epsilon 3 accessory subunit	DPOE3_HUMAN	Histone chaperone	#	CHRAC	#	#
PPARGC1A	Pfam-B_19319 PB019319 241-286 RRM_1 PF00076 679-742	PRGC1_MOUSE	peroxisome proliferator-activated receptor gamma coactivator 1 alpha	PRGC1_HUMAN	Histone modification cofactor	#	#	#	#
PPM1G	PP2C PF00481 25-120 264-492	PPM1G_MOUSE	protein phosphatase Mg2+/Mn2+ dependent 1G	PPM1G_HUMAN	Chromatin remodelling	#	#	#	#
PPP2CA	Metallophos PF00149 50-245	PP2AA_MOUSE	protein phosphatase 2 catalytic subunit alpha isozyme	PP2AA_HUMAN	Histone modification write	Histone phosphorylation	#	H2AX	H2AXph
PPP4C	Metallophos PF00149 47-242	PP4C_MOUSE	protein phosphatase 4 catalytic subunit	PP4C_HUMAN	Histone modification erase	Histone phosphorylation	PPP4C-PPP4R2-PPP4R3A	H2AXS139ph	H2AXS139
PPP4R2	PPP4R2 PF09184 2-267	PP4R2_MOUSE	protein phosphatase 4 regulatory subunit 2	PP4R2_HUMAN	Histone modification cofactor	#	PPP4C-PPP4R2-PPP4R3A	#	#
PRDM1	SET PF00856 99-201 zf-H2C2_2 PF13465 589-614 617-642 645-670	PRDM1_MOUSE	PR domain containing 1 with ZNF domain	PRDM1_HUMAN	Histone modification write cofactor	Histone methylation	#	H3K9	H3K9me
PRDM2	Pfam-B_29325 PB029325 1053-1085 SET PF00856 41-141 zf-C2H2 PF00096 390-412 zf-C2H2_4 PF13894 360-383 483-506 1134-1157 1191-1214 1455-1475	#	PR domain containing 2 with ZNF domain	PRDM2_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me
PRDM4	Pfam-B_13260 PB013260 461-509 zf-C2H2 PF00096 730-752 zf-H2C2_2 PF13465 632-657 660-683 688-713	PRDM4_MOUSE	PR domain containing 4	PRDM4_HUMAN	Histone modification write	Histone methylation	#	H4R3	H4R3me2s
PRDM5	zf-C2H2 PF00096 199-221 262-287 603-625 zf-C2H2_4 PF13894 167-190 zf-C2H2_jaz PF12171 375-399 zf-H2C2_2 PF13465 334-359 418-443 446-472 475-500 503-528 531-556 559-583 zf-met PF12874 234-254 295-317	PRDM5_MOUSE	PR domain containing 5	PRDM5_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me
PRDM6	SET PF00856 259-365 zf-C2H2 PF00096 501-523 zf-C2H2_4 PF13894 473-495 zf-H2C2_2 PF13465 543-568	PRDM6_MOUSE	PR domain containing 6	PRDM6_HUMAN	Histone modification write	Histone methylation	#	H3R2 H4K20	H3R2me1 H3R2me2 H4K20me1
PRDM7	KRAB PF01352 27-65 SSXRD PF09514 170-202	#	PR domain containing 7	PRDM7_HUMAN	Histone modification write	Histone methylation	#	#	#
PRDM8	zf-C2H2 PF00096 627-648 666-688	PRDM8_MOUSE	PR domain containing 8	PRDM8_HUMAN	Histone modification write	Histone methylation	#	#	#
PRDM9	KRAB PF01352 27-65 SSXRD PF09514 170-202 zf-C2H2 PF00096 860-882 zf-H2C2_2 PF13465 540-562 566-590 594-619 622-647 650-674 678-702 706-731 734-758 762-786 790-815 818-843 846-871	PRDM9_MOUSE	PR domain containing 9	PRDM9_HUMAN	Histone modification write	Histone methylation	#	H3K4	H3K4me3
PRDM11	Pfam-B_3219 PB003219 1-353	PRD11_MOUSE	PR domain containing 11	PRD11_HUMAN	Histone modification write	Histone methylation	#	#	#
PRDM12	Pfam-B_39033 PB039033 1-49 zf-H2C2_2 PF13465 257-282 285-310	PRD12_MOUSE	PR domain containing 12	PRD12_HUMAN	Histone modification write cofactor	Histone methylation	#	H3K9	H3K9me
PRDM13	zf-C2H2 PF00096 137-160 zf-H2C2_2 PF13465 587-611 615-641	PRD13_MOUSE	PR domain containing 13	PRD13_HUMAN	Histone modification write	Histone methylation	#	#	#
PRDM14	SET PF00856 265-367 zf-C2H2 PF00096 546-568 zf-C2H2_4 PF13894 400-421 432-455 zf-H2C2_2 PF13465 475-500 504-528	PRD14_MOUSE	PR domain containing 14	PRD14_HUMAN	DNA modification	DNA demethylation	#	mC	#
PRDM16	Pfam-B_2662 PB002662 14-127 zf-C2H2 PF00096 337-360 366-388 394-416 423-445 979-1002 1008-1032 zf-C2H2_6 PF13912 229-255 zf-H2C2_2 PF13465 295-319 965-989	PRD16_MOUSE	PR domain containing 16	PRD16_HUMAN	Histone modification write cofactor TF	Histone methylation TF repressor	#	H3K9 DNA motif	H3K9me
PRKAA1	Pfam-B_8588 PB008588 351-524 Pkinase PF00069 27-279	AAPK1_MOUSE	protein kinase AMP-activated alpha 1 catalytic subunit	AAPK1_HUMAN	Histone modification write	Histone phosphorylation	#	H2BS36	H2BS36ph
PRKAA2	Pkinase PF00069 16-268	AAPK2_MOUSE	protein kinase AMP-activated alpha 2 catalytic subunit	AAPK2_HUMAN	Histone modification write	Histone phosphorylation	#	H2BS36	H2BS36ph
PRKAB1	AMPKBI PF04739 149-270	AAKB1_MOUSE	protein kinase AMP-activated beta 1 non-catalytic subunit	AAKB1_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	#	#
PRKAB2	AMPKBI PF04739 155-272	AAKB2_MOUSE	protein kinase AMP-activated beta 2 non-catalytic subunit	AAKB2_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	#	#
PRKAG1	CBS PF00571 39-97 118-178 187-252 263-324	AAKG1_MOUSE	protein kinase AMP-activated gamma 1 non-catalytic subunit	AAKG1_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	#	#
PRKAG2	CBS PF00571 350-410 428-484 494-556 Pfam-B_5182 PB005182 268-349	AAKG2_MOUSE	protein kinase AMP-activated gamma 2 non-catalytic subunit	AAKG2_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	#	#
PRKAG3	CBS PF00571 273-333 350-406 414-479	AAKG3_MOUSE	protein kinase AMP-activated gamma 3 non-catalytic subunit	AAKG3_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	#	#
PRKCA	C1_1 PF00130 37-89 102-154 C2 PF00168 173-260 Pkinase PF00069 339-597 Pkinase_C PF00433 622-662	KPCA_MOUSE	protein kinase C alpha	KPCA_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	H3	#
PRKCB	C1_1 PF00130 37-89 102-154 C2 PF00168 173-260 Pkinase PF00069 342-600 Pkinase_C PF00433 620-666	KPCB_MOUSE	protein kinase C beta	KPCB_HUMAN	Histone modification write	Histone methylation	#	H3T6	H3T6ph
PRKCD	C1_1 PF00130 159-211 231-283 Pkinase PF00069 349-603 Pkinase_C PF00433 623-669	KPCD_MOUSE	protein kinase C delta	KPCD_HUMAN	Histone modification	#	#	#	#
PRKDC	FAT PF02259 3023-3470 FATC PF02260 4096-4128 NUC194 PF08163 1813-2210 PI3_PI4_kinase PF00454 3747-4015 Pfam-B_14440 PB014440 411-472 Pfam-B_1565 PB001565 131-345 Pfam-B_9125 PB009125 2650-2694	PRKDC_MOUSE	protein kinase DNA-activated catalytic polypeptide	PRKDC_HUMAN	Histone modification write	Histone phosphorylation	#	H2AXS139 H2AFXS139	H2AXS139ph H2AFXS139ph
PRMT1	Methyltransf_31 PF13847 76-216	ANM1_MOUSE	protein arginine methyltransferase 1	ANM1_HUMAN	Histone modification write	Histone methylation	#	H4R3	H4R3me1 H4R3me2a
PRMT2	PRMT5 PF05185 114-415 SH3_9 PF14604 37-84	ANM2_MOUSE	protein arginine methyltransferase 2	ANM2_HUMAN	Histone modification write	Histone methylation	#	H4	H4me
PRMT5	PRMT5 PF05185 181-619 Pfam-B_18578 PB018578 1-49	ANM5_MOUSE	protein arginine methyltransferase 5	ANM5_HUMAN	Histone modification write	Histone methylation	methylosome	H3R8 H4R3	H3R8me H4R3me
PRMT6	Methyltransf_18 PF12847 82-189	ANM6_MOUSE	protein arginine methyltransferase 6	ANM6_HUMAN	Histone modification write	Histone methylation	#	H2AR3 H3R2 H4R4	H2AR3me H4R3me H3R2me2a
PRMT7	Pfam-B_13426 PB013426 301-359 PrmA PF06325 54-149	ANM7_MOUSE	protein arginine methyltransferase 7	ANM7_HUMAN	Histone modification write	Histone methylation	#	H2A H4R3	H2A H4R3me2
PRMT8	PrmA PF06325 102-200	ANM8_MOUSE	protein arginine methyltransferase 8	ANM8_HUMAN	Histone modification write	Histone methylation	#	H4R	H4Rme
PRMT9	PrmA PF06325 167-257 TPR_11 PF13414 67-132	ANM9_MOUSE	protein arginine methyltransferase 9	ANM9_HUMAN	Histone modification write	Histone methylation	#	H4R3	H4R3me2
PRPF31	NOSIC PF08060 92-144 Nop PF01798 186-334 Pfam-B_23523 PB023523 1-44 Prp31_C PF09785 336-465	PRP31_MOUSE	pre-mRNA processing factor 31	PRP31_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	#	#
PRR14	Tantalus PF15386 457-517	PRR14_MOUSE	proline rich 14	PRR14_HUMAN	Histone modification write	Histone phosphorylation	#	H3K9me2 H3K9me3	#
PSIP1	LEDGF PF11467 349-455 PWWP PF00855 5-87	PSIP1_MOUSE	PC4 and SFRS1 interacting protein 1	PSIP1_HUMAN	Chromatin remodelling	#	#	#	#
RAD51	HHH_5 PF14520 28-80 Rad51 PF08423 83-338	RAD51_MOUSE	RAD51 recombinase	RAD51_HUMAN	Histone modification erase	Histone ubiquitination	BRCC	histone	#
RAD54B	Helicase_C PF00271 678-758 Pfam-B_10171 PB010171 772-829 SNF2_N PF00176 299-598	RA54B_MOUSE	RAD54 homolog B (S. cerevisiae)	RA54B_HUMAN	Chromatin remodelling	#	#	#	#
RAD54L	Helicase_C PF00271 531-611 Pfam-B_14570 PB014570 674-743 Rad54_N PF08658 33-138 SNF2_N PF00176 156-463	RAD54_MOUSE	RAD54-like (S. cerevisiae)	RAD54_HUMAN	Chromatin remodelling	#	#	#	#
RAD54L2	Helicase_C PF00271 774-854 Pfam-B_2830 PB002830 105-259 SNF2_N PF00176 274-625	ARIP4_MOUSE	RAD54-like 2 (S. cerevisiae)	ARIP4_HUMAN	Chromatin remodelling	#	#	#	#
RAG1	Pfam-B_793 PB000793 1-89 RAG1 PF12940 513-953 zf-C3HC4 PF00097 293-331 zf-RAG1 PF10426 354-383	RAG1_MOUSE	recombination activating gene 1	RAG1_HUMAN	Histone modification write	Histone ubiquitination	#	H3.3K DNA motif	H3.3Kub
RAG2	RAG2 PF03089 51-389 RAG2_PHD PF13341 414-491	RAG2_MOUSE	recombination activating gene 2	RAG2_HUMAN	Histone modification read	#	#	H3K4me3	#
RAI1	Pfam-B_11259 PB011259 438-596 Pfam-B_27361 PB027361 388-436 Pfam-B_6090 PB006090 1665-1710 zf-HC5HC2H PF13771 1825-1903	RAI1_MOUSE	retinoic acid induced 1	RAI1_HUMAN	Chromatin remodelling	#	#	#	#
RARA	Hormone_recep PF00104 207-409 zf-C4 PF00105 86-155	RARA_MOUSE	retinoic acid receptor alpha	RARA_HUMAN	Histone modification write cofactor TF TF	Histone methylation TF activator TF repressor	#	H3K4	H3K4me H3K4me2
RB1	DUF3452 PF11934 105-229 RB_A PF01858 373-573 RB_B PF01857 645-766 Rb_C PF08934 768-927	RB_MOUSE	retinoblastoma 1	RB_HUMAN	Chromatin remodelling Histone modification write	# Histone ubiquitination	CREST-BRG1 L3MBTL1	#	#
RBBP4	CAF1C_H4-bd PF12265 18-89 WD40 PF00400 167-206 218-256 263-302 307-346 364-403	RBBP4_MOUSE	retinoblastoma binding protein 4	RBBP4_HUMAN	Histone chaperone	#	NuRF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm NuRD mSin3A core HDAC mSin3A-like complex PRC2 CAF-1	H4	#
RBBP5	Pfam-B_3428 PB003428 121-325 WD40 PF00400 23-52 58-94	RBBP5_MOUSE	retinoblastoma binding protein 5	RBBP5_HUMAN	Histone modification write cofactor	Histone methylation	COMPASS Menin-associated_HMT MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7 COMPASS-like MLL3 4	H3K4	H3K4me1 H3K4me2 H3K4me3
RBBP7	CAF1C_H4-bd PF12265 17-88 WD40 PF00400 166-205 217-255 262-301 306-345 363-402	RBBP7_MOUSE	retinoblastoma binding protein 7	RBBP7_HUMAN	Histone chaperone	#	NuRF NuRD mSin3A core HDAC mSin3A-like complex PRC2	H4	#
RBX1	zf-rbx1 PF12678 21-98	RBX1_MOUSE	ring-box 1 E3 ubiquitin protein ligase	RBX1_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	H3 H4	H3ub H4ub
RCC1	RCC1 PF00415 34-82 85-134 137-187 190-255 258-309 312-360 363-414	RCC1_MOUSE	regulator of chromosome condensation 1	RCC1_HUMAN	Chromatin remodelling	#	#	H2A H2B	#
RCOR1	ELM2 PF01448 102-157 Myb_DNA-binding PF00249 381-425	RCOR1_MOUSE	REST corepressor 1	RCOR1_HUMAN	Histone modification erase cofactor Histone modification erase cofactor	Histone acetylation Histone methylation	BHC SCL LSD-CoREST	#	#
RCOR3	ELM2 PF01448 1-54 Myb_DNA-binding PF00249 288-332	RCOR3_MOUSE	REST corepressor 3	RCOR3_HUMAN	Histone modification erase cofactor	Histone acetylation	LSD-CoREST	#	#
REST	Pfam-B_2325 PB002325 821-909 Pfam-B_9727 PB009727 1001-1095 zf-C2H2_4 PF13894 216-238 zf-H2C2_2 PF13465 290-315 318-343 346-372	REST_MOUSE	RE1-silencing transcription factor	REST_HUMAN	Histone modification erase cofactor TF TF	Histone acetylation TF activator TF repressor	#	DNA motif	#
RING1	Pfam-B_11743 PB011743 292-404 Pfam-B_13488 PB013488 241-291 Pfam-B_23468 PB023468 191-239 zf-C3HC4 PF00097 48-87	RING1_MOUSE	ring finger protein 1	RING1_HUMAN	Histone modification write Polycomb group (PcG) protein	Histone ubiquitination #	PRC1 BCOR RING2-L3MBTL2 RING2-FBRS	H2AK119	H2AK119ub
RLIM	zf-RING_2 PF13639 568-611	RNF12_MOUSE	ring finger protein LIM domain interacting	RNF12_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
RMI1	DUF1767 PF08585 12-104 Pfam-B_227 PB000227 590-623	RMI1_MOUSE	RecQ mediated genome instability 1	RMI1_HUMAN	DNA modification	#	#	#	#
RNF2	zf-C3HC4 PF00097 51-90	RING2_MOUSE	ring finger protein 2	RING2_HUMAN	Histone modification write	Histone ubiquitination	PRC1 BCOR RING2-L3MBTL2 RING2-FBRS CHD8 MLL2/3 MLL4/WBP7	H2AK119	H2AK119ub
RNF8	FHA PF00498 38-109 zf-RING_2 PF13639 401-441	RNF8_MOUSE	ring finger protein 8 E3 ubiquitin protein ligase	RNF8_HUMAN	Histone modification write	Histone ubiquitination	#	H2AK63 H2AXK63 H2AK48 H2AXK48	H2AK63ub H2AXK63ub H2AK48ub H2AXK48ub
RNF20	Pfam-B_13436 PB013436 97-179 Pfam-B_14933 PB014933 35-95 Pfam-B_6844 PB006844 735-892 zf-C3HC4 PF00097 922-960	BRE1A_MOUSE	ring finger protein 20 E3 ubiquitin protein ligase	BRE1A_HUMAN	Histone modification write	Histone ubiquitination	#	H2BK120	H2BK120ub1
RNF40	Pfam-B_21314 PB021314 191-299 Pfam-B_9159 PB009159 1-189 zf-C3HC4 PF00097 948-986	BRE1B_MOUSE	ring finger protein 40 E3 ubiquitin protein ligase	BRE1B_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	H2BK121	H2BK120ub2
RNF168	Pfam-B_30754 PB030754 528-566 zf-C3HC4_2 PF13923 16-54	RN168_MOUSE	ring finger protein 168 E3 ubiquitin protein ligase	RN168_HUMAN	Histone modification write	Histone ubiquitination	#	H2AK13 H2AK15 H2AXK13 H2AXK15	H2AK13ub H2AK15ub H2AXK13ub H2AXK15ub
RPS6KA3	Pkinase PF00069 68-327 422-679 Pkinase_C PF00433 349-389	KS6A3_MOUSE	ribosomal protein S6 kinase 90kDa polypeptide 3	KS6A3_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	H3S10	H3S10ph
RPS6KA4	Pkinase PF00069 33-301 413-674 Pkinase_C PF00433 321-365	KS6A4_MOUSE	ribosomal protein S6 kinase 90kDa polypeptide 4	KS6A4_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10 H3S28	H3S10ph H3S28ph
RPS6KA5	Pkinase PF00069 49-318 427-687 Pkinase_C PF00433 338-381	KS6A5_MOUSE	ribosomal protein S6 kinase 90kDa polypeptide 5	KS6A5_HUMAN	Histone modification write	Histone phosphorylation	#	H2AS1 H3S10 H3S28	H2AS1ph H3S10ph H3S28ph
RRP8	Methyltransf_8 PF05148 237-456	RRP8_MOUSE	ribosomal RNA processing 8 methyltransferase homolog (yeast)	RRP8_HUMAN	Histone modification cofactor	#	eNoSc	H3ac	H3K9me2
RSF1	PHD PF00628 893-941 WHIM1 PF15612 98-148 WHIM2 PF15613 150-182 WHIM3 PF15614 188-409	#	remodeling and spacing factor 1	RSF1_HUMAN	Histone modification read	#	RSF	#	#
RUVBL1	TIP49 PF06068 14-416	RUVB1_MOUSE	RuvB-like AAA ATPase 1	RUVB1_HUMAN	Chromatin remodelling Histone modification write	# Histone phosphorylation	Ino80 SWR NuA4 NuA4-related complex CHD8 MLL2/3 MLL4/WBP7 SRCAP	#	#
RUVBL2	TIP49 PF06068 21-412	RUVB2_MOUSE	RuvB-like AAA ATPase 2	RUVB2_HUMAN	Chromatin remodelling cofactor	#	Ino80 SWR NuA4 NuA4-related complex CHD8 MLL2/3 MLL4/WBP7 SRCAP	#	#
RYBP	Pfam-B_18067 PB018067 49-226 zf-RanBP PF00641 22-48	RYBP_MOUSE	RING1 and YY1 binding protein	RYBP_HUMAN	Polycomb group (PcG) protein	#	BCOR RING2-L3MBTL2 RING2-FBRS	#	#
SAFB	Pfam-B_12198 PB012198 66-89 RRM_6 PF14259 409-478 SAP PF02037 31-65	SAFB1_MOUSE	scaffold attachment factor B	SAFB1_HUMAN	Chromatin remodelling	#	#	#	#
SAP18	SAP18 PF06487 16-137	SAP18_MOUSE	Sin3A-associated protein 18kDa	SAP18_HUMAN	Histone modification erase cofactor	Histone acetylation	mSin3A	#	#
SAP25	SAP25 PF15476 1-199	SAP25_MOUSE	Sin3A-associated protein 25kDa	SAP25_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
SAP30	SAP30_Sin3_bdg PF13867 153-205 zf-SAP30 PF13866 56-134	SAP30_MOUSE	Sin3A-associated protein 30kDa	SAP30_HUMAN	Histone modification erase cofactor	Histone acetylation	mSin3A mSin3A-like complex	#	#
SAP30L	SAP30_Sin3_bdg PF13867 114-166 zf-SAP30 PF13866 18-95	SP30L_MOUSE	SAP30-like	SP30L_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
SAP130	Pfam-B_10398 PB010398 431-719 Pfam-B_13351 PB013351 101-249 Pfam-B_17122 PB017122 781-837 Pfam-B_18714 PB018714 721-779 Pfam-B_237 PB000237 949-984	SP130_MOUSE	Sin3A-associated protein 130kDa	SP130_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
SATB1	CUT PF02376 362-448 485-571 Homeobox PF00046 645-702 Pfam-B_9146 PB009146 141-299	SATB1_MOUSE	SATB homeobox 1	SATB1_HUMAN	Chromatin remodelling cofactor	#	#	#	#
SATB2	CUT PF02376 352-437 474-560 Homeobox PF00046 615-672 Pfam-B_8103 PB008103 1-268	SATB2_MOUSE	SATB homeobox 2	SATB2_HUMAN	Chromatin remodelling cofactor	#	#	#	#
SCMH1	DUF3588 PF12140 355-469 MBT PF02820 62-134 171-239 SAM_1 PF00536 591-656	SCMH1_MOUSE	sex comb on midleg homolog 1 (Drosophila)	SCMH1_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
SCML2	DUF3588 PF12140 353-468 MBT PF02820 67-139 176-244 SAM_1 PF00536 629-695	#	sex comb on midleg-like 2 (Drosophila)	SCML2_HUMAN	Polycomb group (PcG) protein	#	PRC1	#	#
SCML4	DUF3588 PF12140 92-208 SAM_1 PF00536 344-410	SCML4_MOUSE	sex comb on midleg-like 4 (Drosophila)	SCML4_HUMAN	Polycomb group (PcG) protein	#	#	#	#
SENP1	Peptidase_C48 PF02902 464-642 Pfam-B_2161 PB002161 1-189 Pfam-B_34931 PB034931 191-249	SENP1_MOUSE	SUMO1/sentrin specific peptidase 1	SENP1_HUMAN	Histone modification erase cofactor	Histone sumoylation	#	H4	#
SENP3	Peptidase_C48 PF02902 400-572 Pfam-B_2161 PB002161 1-349	SENP3_MOUSE	SUMO1/sentrin/SMT3 specific peptidase 3	SENP3_HUMAN	Histone modification erase Histone modification write cofactor	Histone sumoylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	H3	H3ac
SET	NAP PF00956 42-237	SET_MOUSE	SET nuclear proto-oncogene	SET_HUMAN	Histone modification	#	#	#	#
SETD1A	N-SET PF11764 1418-1558 Pfam-B_24657 PB024657 752-1010 Pfam-B_24930 PB024930 331-410 Pfam-B_41492 PB041492 622-680 RRM_1 PF00076 99-166 SET PF00856 1579-1685	#	SET domain containing 1A	SET1A_HUMAN	Histone modification write	Histone methylation	COMPASS	H3K4	H3K4me
SETD1B	N-SET PF11764 1629-1774 Pfam-B_1367 PB001367 1017-1148 Pfam-B_14013 PB014013 887-1015 RRM_1 PF00076 108-175 SET PF00856 1795-1901	SET1B_MOUSE	SET domain containing 1B	SET1B_HUMAN	Histone modification write	Histone methylation	COMPASS	H3K4	H3K4me
SETD2	Pfam-B_18604 PB018604 305-521 Pfam-B_22486 PB022486 541-599 Pfam-B_2796 PB002796 2146-2339 Pfam-B_3607 PB003607 1826-2144 Pfam-B_67824 PB067824 31-77 SET PF00856 1561-1667 SRI PF08236 2465-2559 WW PF00397 2391-2420	SETD2_MOUSE	SET domain containing 2	SETD2_HUMAN	Histone modification write	Histone methylation	#	H3K36me2	H3K36me3
SETD3	Rubis-subs-bind PF09273 343-475 SET PF00856 105-314	SETD3_MOUSE	SET domain containing 3	SETD3_HUMAN	Histone modification write	Histone methylation	#	H3K36	H3K36me
SETD5	Pfam-B_7713 PB007713 700-789 SET PF00856 285-390	SETD5_MOUSE	SET domain containing 5	SETD5_HUMAN	Histone modification write	Histone methylation	#	#	#
SETD6	Pfam-B_25912 PB025912 1-69 Rubis-subs-bind PF09273 329-465 SET PF00856 74-286	SETD6_MOUSE	SET domain containing 6	SETD6_HUMAN	Chromatin remodelling Histone modification write	# Histone methylation	#	#	#
SETD7	MORN PF02493 13-35 36-58 60-81 106-128 SET PF00856 227-336	SETD7_MOUSE	SET domain containing (lysine methyltransferase) 7	SETD7_HUMAN	Histone modification write	Histone methylation	#	H3K4	H3K4me1
SETD8	SET PF00856 268-378	SETD8_MOUSE	SET domain containing (lysine methyltransferase) 8	SETD8_HUMAN	Histone modification write	Histone methylation	#	H4K20	H4K20me1
SETDB1	MBD PF01429 594-668 Pfam-B_23747 PB023747 365-520 Pfam-B_27578 PB027578 341-364 Pre-SET PF05033 681-795 SET PF00856 814-1266	SETB1_MOUSE	SET domain bifurcated 1	SETB1_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me3
SETDB2	MBD PF01429 160-232 Pre-SET PF05033 245-359 SET PF00856 378-694	SETB2_MOUSE	SET domain bifurcated 2	SETB2_HUMAN	Histone modification write	Histone methylation	#	H3K9	H3K9me3
SETMAR	HTH_Tnp_Tc3_2 PF01498 401-466 Pre-SET PF05033 16-118 SET PF00856 137-250 Transposase_1 PF01359 488-568	SETMR_MOUSE	SET domain and mariner transposase fusion gene	SETMR_HUMAN	Histone modification write	Histone methylation	#	H3K4 H3K36	H3K4me H3K36me
SF3B1	Pfam-B_1720 PB001720 1099-1147 SF3b1 PF08920 282-457	SF3B1_MOUSE	splicing factor 3b subunit 1 155kDa	SF3B1_HUMAN	RNA modification	#	B-WICH	#	#
SF3B3	CPSF_A PF03178 863-1184 MMS1_N PF10433 76-597	SF3B3_MOUSE	splicing factor 3b subunit 3 130kDa	SF3B3_HUMAN	RNA modification	#	#	#	#
SFMBT1	DUF3588 PF12140 501-620 MBT PF02820 54-128 167-240 279-356 388-461 Pfam-B_19576 PB019576 672-751 SAM_1 PF00536 794-857	SMBT1_MOUSE	Scm-like with four mbt domains 1	SMBT1_HUMAN	Polycomb group (PcG) protein	#	SCL	H4K20	#
SFMBT2	DUF3588 PF12140 527-646 MBT PF02820 78-152 191-263 304-380 412-485 SAM_1 PF00536 822-885	SMBT2_MOUSE	Scm-like with four mbt domains 2	SMBT2_HUMAN	Histone modification read Polycomb group (PcG) protein TF	# # TF repressor	#	H3K9me2 H3K9me3 H3K27me3 H4K20me2 H4K20me3	H3 H4
SFPQ	NOPS PF08075 444-495 RRM_1 PF00076 299-363 373-440	SFPQ_MOUSE	splicing factor proline/glutamine-rich	SFPQ_HUMAN	Chromatin remodelling cofactor RNA modification TF	# # TF repressor	#	#	#
SHPRH	Helicase_C PF00271 1545-1622 Linker_histone PF00538 438-512 Pfam-B_11163 PB011163 1-248 SNF2_N PF00176 307-987 zf-C3HC4_2 PF13923 1432-1478	SHPRH_MOUSE	SNF2 histone linker PHD RING helicase E3 ubiquitin protein ligase	SHPRH_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	#	#
SIN3A	PAH PF02671 141-187 322-381 477-523 Pfam-B_10250 PB010250 1-99 Pfam-B_10714 PB010714 1098-1128 Pfam-B_8471 PB008471 1055-1090 Sin3_corepress PF08295 550-650	SIN3A_MOUSE	SIN3 transcription regulator family member A	SIN3A_HUMAN	Histone modification erase cofactor TF TF	Histone acetylation TF activator TF repressor	SWI/SNF_Brg1(I) SWI/SNF_Brm mSin3A mSin3A-like complex	DNA motif	#
SIN3B	PAH PF02671 59-105 180-236 321-367 Sin3_corepress PF08295 393-448 450-525	SIN3B_MOUSE	SIN3 transcription regulator family member B	SIN3B_HUMAN	Histone modification erase cofactor TF	Histone acetylation TF repressor	mSin3A	DNA motif	#
SIRT1	Pfam-B_28511 PB028511 1-109 Pfam-B_5913 PB005913 111-189 Pfam-B_8042 PB008042 611-745 SIR2 PF02146 261-447	SIR1_MOUSE	sirtuin 1	SIR1_HUMAN	Histone modification erase Histone modification write cofactor	Histone acetylation Histone methylation	eNoSc	H1K26ac H3K9ac H4K16ac	H1K26 H3K9 H4K16
SIRT2	SIR2 PF02146 84-268	SIR2_MOUSE	sirtuin 2	SIR2_HUMAN	Histone modification erase Histone modification write cofactor	Histone acetylation Histone methylation	#	H3K18ac H3K56ac H4K16ac H4K20me1	H3K18 H3K56 H4K16 H4K20me2 H4K20me3
SIRT6	SIR2 PF02146 52-89 80-221	SIR6_MOUSE	sirtuin 6	SIR6_HUMAN	Histone modification erase	Histone acetylation	#	H3K9ac H3K56ac	H3K9 H3K56
SIRT7	SIR2 PF02146 133-275	SIR7_MOUSE	sirtuin 7	SIR7_HUMAN	Histone modification erase	Histone acetylation	B-WICH	H3K18ac	H3K18
SKP1	Skp1 PF01466 85-162 Skp1_POZ PF03931 2-67	SKP1_MOUSE	S-phase kinase-associated protein 1	SKP1_HUMAN	Histone modification write cofactor	Histone ubiquitination	BCOR	#	#
SMARCA1	DBINO PF13892 42-119 HAND PF09110 758-856 Helicase_C PF00271 520-612 SLIDE PF09111 912-1028 SNF2_N PF00176 186-466	SMCA1_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 1	SMCA1_HUMAN	Chromatin remodelling Histone modification erase	# Histone acetylation	NuRF CERF CERF	#	#
SMARCA2	BRK PF07533 588-633 Bromodomain PF00439 1411-1493 HSA PF07529 436-508 Helicase_C PF00271 1084-1164 Pfam-B_17897 PB017897 1369-1398 Pfam-B_2366 PB002366 333-414 QLQ PF08880 172-208 SNF2_N PF00176 727-1022 SnAC PF14619 1257-1326	SMCA2_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 2	SMCA2_HUMAN	Histone modification read TF	# TF activator	BAF nBAF npBAF WINAC bBAF SWI/SNF BRM-BRG1	H3 DNA motif	#
SMARCA4	BRK PF07533 610-655 Bromodomain PF00439 1462-1551 HSA PF07529 460-532 Helicase_C PF00271 1114-1194 QLQ PF08880 170-206 SNF2_N PF00176 757-1052 SnAC PF14619 1321-1389	SMCA4_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 4	SMCA4_HUMAN	Histone modification read TF	# TF activator	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1 CREST-BRG1	H3 H4	#
SMARCA5	DBINO PF13892 58-116 HAND PF09110 743-841 Helicase_C PF00271 517-597 Pfam-B_36230 PB036230 1-39 SLIDE PF09111 897-1013 SNF2_N PF00176 183-463	SMCA5_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 5	SMCA5_HUMAN	Chromatin remodelling	#	ACF B-WICH RSF CHRAC NoRC	#	#
SMARCAD1	Helicase_C PF00271 888-967 Pfam-B_295 PB000295 41-308 SNF2_N PF00176 500-788	SMRCD_MOUSE	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily a containing DEAD/H box 1	SMRCD_HUMAN	Chromatin remodelling	#	#	#	#
SMARCAL1	HARP PF07443 248-302 343-397 Helicase_C PF00271 743-822 Pfam-B_7889 PB007889 1-159 SNF2_N PF00176 434-716	SMAL1_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a-like 1	SMAL1_HUMAN	Chromatin remodelling	#	#	#	#
SMARCB1	Pfam-B_9879 PB009879 2-146 SNF5 PF04855 178-373	SNF5_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily b member 1	SNF5_HUMAN	Histone modification read	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1	H3K56	#
SMARCC1	Myb_DNA-binding PF00249 620-665 SWIRM PF04433 449-537	SMRC1_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 1	SMRC1_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1	#	#
SMARCC2	Myb_DNA-binding PF00249 598-643 Pfam-B_1849 PB001849 1-168 SWIRM PF04433 424-512	SMRC2_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 2	SMRC2_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1	#	#
SMARCD1	Pfam-B_13759 PB013759 1-79 Pfam-B_3130 PB003130 378-473 SWIB PF02201 291-366	SMRD1_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 1	SMRD1_HUMAN	Chromatin remodelling	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB SWI/SNF BRM-BRG1	#	#
SMARCD2	Pfam-B_13705 PB013705 420-516 Pfam-B_7929 PB007929 141-287 SWIB PF02201 307-382	SMRD2_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 2	SMRD2_HUMAN	Chromatin remodelling cofactor	#	BAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brm SWI/SNF-like EPAFB bBAF SWI/SNF BRM-BRG1	#	#
SMARCD3	Pfam-B_18257 PB018257 7-73 Pfam-B_3130 PB003130 346-441 SWIB PF02201 259-334	SMRD3_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 3	SMRD3_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brm SWI/SNF BRM-BRG1	#	#
SMARCE1	HMG_box PF00505 66-134 Pfam-B_14199 PB014199 371-409	SMCE1_MOUSE	SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1	SMCE1_HUMAN	Chromatin remodelling cofactor	#	BAF nBAF npBAF PBAF SWI/SNF_Brg1(I) SWI/SNF_Brg1(II) SWI/SNF_Brm SWI/SNF-like_EPAFa WINAC SWI/SNF-like EPAFB bBAF	#	#
SMEK1	Pfam-B_1700 PB001700 381-501 Pfam-B_334 PB000334 506-611 SMK-1 PF04802 164-357	P4R3A_MOUSE	SMEK homolog 1 suppressor of mek1 (Dictyostelium)	P4R3A_HUMAN	Histone modification erase cofactor	Histone phosphorylation	PPP4C-PPP4R2-PPP4R3A	H2AFX	#
SMEK2	Pfam-B_2986 PB002986 536-638 SMK-1 PF04802 166-359	P4R3B_MOUSE	SMEK homolog 2 suppressor of mek1 (Dictyostelium)	P4R3B_HUMAN	Histone modification erase cofactor	Histone phosphorylation	#	H2AFX	#
SMYD1	SET PF00856 18-253 zf-MYND PF01753 52-90	SMYD1_MOUSE	SET and MYND domain containing 1	SMYD1_HUMAN	Histone modification write	Histone methylation	#	H3K4	H3K4me
SMYD2	SET PF00856 18-241 zf-MYND PF01753 52-90	SMYD2_MOUSE	SET and MYND domain containing 2	SMYD2_HUMAN	Histone modification write	Histone methylation	#	H3K4 H3K36	H3K4me H3K36me2
SMYD3	Pfam-B_27974 PB027974 391-422 SET PF00856 15-240 zf-MYND PF01753 47-87	SMYD3_MOUSE	SET and MYND domain containing 3	SMYD3_HUMAN	Histone modification write	Histone methylation	#	H3K4 H3K5	H3K4me2 H3K4me3 H3K5me2 H3K5me3
SMYD4	Pfam-B_24699 PB024699 740-795 Pfam-B_50317 PB050317 1-65 SET PF00856 244-574 TPR_11 PF13414 66-135 zf-MYND PF01753 296-335	SMYD4_MOUSE	SET and MYND domain containing 4	SMYD4_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
SNAI2	zf-C2H2 PF00096 159-181 zf-C2H2_6 PF13912 127-153 zf-H2C2_2 PF13465 199-224 227-252	SNAI2_MOUSE	snail family zinc finger 2	SNAI2_HUMAN	Histone modification erase cofactor	#	#	#	#
SP1	Pfam-B_20467 PB020467 61-148 Pfam-B_7620 PB007620 371-482 zf-C2H2 PF00096 626-650 686-708 zf-H2C2_2 PF13465 672-695	SP1_MOUSE	Sp1 transcription factor	SP1_HUMAN	Chromatin remodelling TF TF	# TF activator TF repressor	CREST-BRG1	DNA motif	#
SP100	HMG_box PF00505 769-837 HMG_box_2 PF09011 684-753 Pfam-B_182547 PB182547 845-873 Pfam-B_41802 PB041802 151-337 SAND PF01342 595-676 Sp100 PF03172 47-150	SP100_MOUSE	SP100 nuclear antigen	SP100_HUMAN	Chromatin remodelling cofactor	#	#	#	#
SP140	Bromodomain PF00439 775-842 PHD PF00628 692-736 SAND PF01342 580-661 Sp100 PF03172 36-139	#	SP140 nuclear body protein	SP140_HUMAN	Histone modification read TF	# #	#	H3	#
SPEN	Pfam-B_1253 PB001253 981-1331 Pfam-B_17673 PB017673 621-899 Pfam-B_17985 PB017985 901-979 Pfam-B_2825 PB002825 1826-1859 RRM_1 PF00076 8-74 337-407 440-507 RRM_5 PF13893 533-587 SPOC PF07744 3509-3630	MINT_MOUSE	spen family transcriptional repressor	MINT_HUMAN	Histone modification erase cofactor TF TF	Histone acetylation TF activator TF repressor	#	#	#
SPOP	BTB PF00651 190-297 MATH PF00917 38-163	SPOP_MOUSE	speckle-type POZ protein	SPOP_HUMAN	Histone modification write	Histone ubiquitination	#	MacroH2A1	MacroH2A1ub
SRCAP	HSA PF07529 125-196 Helicase_C PF00271 2077-2156 SNF2_N PF00176 621-907	#	Snf2-related CREBBP activator protein	SRCAP_HUMAN	Chromatin remodelling Histone modification erase	# Histone acetylation	NuA4-related complex SRCAP	H2A.Z	#
SRSF1	Pfam-B_5206 PB005206 192-246 RRM_1 PF00076 18-85 123-186	SRSF1_MOUSE	serine/arginine-rich splicing factor 1	SRSF1_HUMAN	RNA modification	#	#	#	#
SRSF3	Pfam-B_13909 PB013909 131-162 RRM_1 PF00076 12-77	SRSF3_MOUSE	serine/arginine-rich splicing factor 3	SRSF3_HUMAN	RNA modification	#	#	#	#
SS18L1	Pfam-B_16193 PB016193 365-394 Pfam-B_22298 PB022298 315-363 SSXT PF05030 11-76	CREST_MOUSE	synovial sarcoma translocation gene on chromosome 18-like 1	CREST_HUMAN	Chromatin remodelling	#	CREST-BRG1	#	#
SS18L2	SSXT PF05030 11-76	S18L2_MOUSE	synovial sarcoma translocation gene on chromosome 18-like 2	S18L2_HUMAN	Chromatin remodelling	#	#	#	#
SSRP1	HMG_box PF00505 547-615 Pfam-B_9245 PB009245 1-73 Rtt106 PF08512 338-428 SSrecog PF03531 74-285	SSRP1_MOUSE	structure specific recognition protein 1	SSRP1_HUMAN	Chromatin remodelling	#	FACT	H3 H4	#
STK4	Mst1_SARAH PF11629 432-480 Pfam-B_12195 PB012195 341-431 Pkinase PF00069 30-281	STK4_MOUSE	serine/threonine kinase 4	STK4_HUMAN	Histone modification write	Histone phosphorylation	#	H2AS14	H2BS14ph
SUDS3	Sds3 PF08598 53-223	SDS3_MOUSE	suppressor of defective silencing 3 homolog (S. cerevisiae)	SDS3_HUMAN	Histone modification erase cofactor	Histone acetylation	mSin3A	#	#
SUPT3H	TFIID-18kDa PF02269 106-198	#	suppressor of Ty 3 homolog (S. cerevisiae)	SUPT3_HUMAN	Histone modification write cofactor	Histone acetylation	PCAF SAGA STAGA	#	#
SUPT6H	DLD PF14878 1050-1160 HHH_7 PF14635 935-1038 HTH_44 PF14641 300-437 Pfam-B_17741 PB017741 172-225 Pfam-B_27919 PB027919 129-149 S1 PF00575 1226-1282 SH2_2 PF14633 1295-1515 SPT6_acidic PF14632 35-128 YqgF PF14639 775-931	SPT6H_MOUSE	suppressor of Ty 6 homolog (S. cerevisiae)	SPT6H_HUMAN	Histone modification erase cofactor	Histone methylation	#	#	#
SUPT7L	Bromo_TP PF07524 151-230 Pfam-B_18361 PB018361 301-379 Pfam-B_18885 PB018885 1-69	ST65G_MOUSE	suppressor of Ty 7 (S. cerevisiae)-like	ST65G_HUMAN	Histone chaperone	#	TFTC-HAT STAGA	#	#
SUPT16H	FACT-Spt16_Nlob PF14826 5-168 Peptidase_M24 PF00557 181-411 Pfam-B_18241 PB018241 958-1024 Rtt106 PF08512 806-896 SPT16 PF08644 529-689	SP16H_MOUSE	suppressor of Ty 16 homolog (S. cerevisiae)	SP16H_HUMAN	Histone modification read	#	WINAC FACT	H2A H2B	#
SUV39H1	Chromo PF00385 43-92 Pre-SET PF05033 135-235 SET PF00856 255-366	SUV91_MOUSE	suppressor of variegation 3-9 homolog 1 (Drosophila)	SUV91_HUMAN	Histone modification write Histone modification write	Histone methylation Histone phosphorylation	eNoSc	H3S10 H3K9me1 H4	H3K9me3
SUV39H2	Chromo PF00385 47-96 Pre-SET PF05033 144-242 SET PF00856 262-373	SUV92_MOUSE	suppressor of variegation 3-9 homolog 2 (Drosophila)	SUV92_HUMAN	Histone modification write	Histone methylation	#	H3K9me1	H3K9me3
SUV420H1	Pfam-B_23340 PB023340 771-839 Pfam-B_24134 PB024134 711-769 Pfam-B_32221 PB032221 551-609 Pfam-B_49669 PB049669 841-883 SET PF00856 99-308	SV421_MOUSE	suppressor of variegation 4-20 homolog 1 (Drosophila)	SV421_HUMAN	Histone modification write	Histone methylation	#	H4K20	H4K20me3
SUV420H2	Pfam-B_18005 PB018005 261-379 Pfam-B_59617 PB059617 1-39 Pfam-B_6511 PB006511 381-460 SET PF00856 121-218	SV422_MOUSE	suppressor of variegation 4-20 homolog 2 (Drosophila)	SV422_HUMAN	Histone modification write	Histone methylation	#	H4K20	H4K20me3
SUZ12	VEFS-Box PF09733 544-681	SUZ12_MOUSE	SUZ12 polycomb repressive complex 2 subunit	SUZ12_HUMAN	Histone modification write cofactor Histone modification write cofactor Polycomb group (PcG) protein TF	Histone methylation Histone ubiquitination # TF repressor	PRC2	DNA motif	#
SYNCRIP	RRM_1 PF00076 164-232 245-312 340-402	HNRPQ_MOUSE	synaptotagmin binding cytoplasmic RNA interacting protein	HNRPQ_HUMAN	RNA modification	mRNA editing	APOB_mRNA_editosome	mRNA	#
TADA1	SAGA-Tad1 PF12767 3-195	TADA1_MOUSE	transcriptional adaptor 1	TADA1_HUMAN	Histone chaperone	#	STAGA	H2A	#
TADA2A	Myb_DNA-binding PF00249 72-118 SWIRM PF04433 362-442	TAD2A_MOUSE	transcriptional adaptor 2A	TAD2A_HUMAN	Histone modification read TF	# TF activator	PCAF ATAC	H3	#
TADA2B	Myb_DNA-binding PF00249 67-113 ZZ PF00569 6-47	#	transcriptional adaptor 2B	TAD2B_HUMAN	Histone modification write cofactor	Histone acetylation	TFTC-HAT	#	#
TADA3	Ada3 PF10198 308-432	TADA3_MOUSE	transcriptional adaptor 3	TADA3_HUMAN	Histone modification write cofactor	Histone acetylation	PCAF TFTC-HAT ATAC STAGA	#	#
TAF1	Bromodomain PF00439 1389-1472 1509-1595 DUF3591 PF12157 565-1028 Pfam-B_10720 PB010720 311-366 TBP-binding PF09247 22-87 zf-CCHC_6 PF15288 1261-1300	TAF1_MOUSE	TAF1 RNA polymerase II TATA box binding protein (TBP)-associated factor 250kDa	TAF1_HUMAN	Histone modification write	Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	H3 H4	H3ac H4ac
TAF1L	Bromodomain PF00439 1408-1491 1528-1614 DUF3591 PF12157 584-1047 Pfam-B_10720 PB010720 330-385 TBP-binding PF09247 21-86 zf-CCHC_6 PF15288 1280-1319	#	TAF1 RNA polymerase II TATA box binding protein (TBP)-associated factor 210kDa-like	TAF1L_HUMAN	Histone modification read	#	#	H1.4ac H2Aac H2Bac H3ac H4ac	#
TAF2	Peptidase_M1 PF01433 21-406 Pfam-B_2101 PB002101 661-979 Pfam-B_21717 PB021717 1111-1159 Pfam-B_6210 PB006210 1161-1197 Pfam-B_8840 PB008840 981-1109	TAF2_MOUSE	TAF2 RNA polymerase II TATA box binding protein (TBP)-associated factor 150kDa	TAF2_HUMAN	TF	#	TFTC-HAT	DNA motif	#
TAF3	Bromo_TP PF07524 3-79 PHD PF00628 867-915	TAF3_MOUSE	TAF3 RNA polymerase II TATA box binding protein (TBP)-associated factor 140kDa	TAF3_HUMAN	Histone modification read	#	#	H3K4me	#
TAF4	Pfam-B_41790 PB041790 141-219 Pfam-B_7817 PB007817 411-499 Pfam-B_906 PB000906 1-139 TAF4 PF05236 834-1084 TAFH PF07531 590-688	#	TAF4 RNA polymerase II TATA box binding protein (TBP)-associated factor 135kDa	TAF4_HUMAN	Histone chaperone	#	TFTC-HAT CHD8 MLL2/3 MLL4/WBP7	#	#
TAF5	Pfam-B_22190 PB022190 61-159 Pfam-B_34937 PB034937 1-59 TFIID_90kDa PF04494 199-338 WD40 PF00400 461-498 533-571 575-613 617-655 659-697 701-739	TAF5_MOUSE	TAF5 RNA polymerase II TATA box binding protein (TBP)-associated factor 100kDa	TAF5_HUMAN	Histone modification write cofactor	Histone acetylation	TFTC-HAT	#	#
TAF5L	TFIID_90kDa PF04494 55-196 WD40 PF00400 259-296 332-370 375-412 416-454 458-496 500-538	TAF5L_MOUSE	TAF5-like RNA polymerase II p300/CBP-associated factor (PCAF)-associated factor 65kDa	TAF5L_HUMAN	Histone modification write cofactor	Histone acetylation	PCAF TFTC-HAT STAGA	#	#
TAF6	DUF1546 PF07571 308-399 Pfam-B_25920 PB025920 618-675 TAF PF02969 11-76	TAF6_MOUSE	TAF6 RNA polymerase II TATA box binding protein (TBP)-associated factor 80kDa	TAF6_HUMAN	Histone chaperone	#	TFTC-HAT CHD8 MLL2/3 MLL4/WBP7	#	#
TAF6L	DUF1546 PF07571 242-333 Pfam-B_32143 PB032143 200-239 Pfam-B_32396 PB032396 161-199 TAF PF02969 9-73	TAF6L_MOUSE	TAF6-like RNA polymerase II p300/CBP-associated factor (PCAF)-associated factor 65kDa	TAF6L_HUMAN	Histone chaperone	#	PCAF TFTC-HAT STAGA	#	#
TAF7	TAFII55_N PF04658 12-178	TAF7_MOUSE	TAF7 RNA polymerase II TATA box binding protein (TBP)-associated factor 55kDa	TAF7_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	#	#
TAF8	Bromo_TP PF07524 29-106 TAF8_C PF10406 144-194	TAF8_MOUSE	TAF8 RNA polymerase II TATA box binding protein (TBP)-associated factor 43kDa	TAF8_HUMAN	Histone chaperone	#	#	#	#
TAF9	TFIID-31kDa PF02291 2-130	TAF9_MOUSE	TAF9 RNA polymerase II TATA box binding protein (TBP)-associated factor 32kDa	TAF9_HUMAN	Histone chaperone	#	PCAF STAGA CHD8 MLL2/3 MLL4/WBP7	#	#
TAF9B	TFIID-31kDa PF02291 2-130	TAF9B_MOUSE	TAF9B RNA polymerase II TATA box binding protein (TBP)-associated factor 31kDa	TAF9B_HUMAN	Histone chaperone	#	TFTC-HAT	#	#
TAF10	TFIID_30kDa PF03540 128-178	TAF10_MOUSE	TAF10 RNA polymerase II TATA box binding protein (TBP)-associated factor 30kDa	TAF10_HUMAN	Histone chaperone Histone modification write	# Histone acetylation	PCAF TFTC-HAT SAGA STAGA	H3 H4	#
TAF12	Pfam-B_25018 PB025018 1-58 TFIID_20kDa PF03847 59-126	TAF12_MOUSE	TAF12 RNA polymerase II TATA box binding protein (TBP)-associated factor 20kDa	TAF12_HUMAN	Histone chaperone Histone modification write	# Histone acetylation	PCAF STAGA	#	#
TBL1XR1	LisH PF08513 6-32 Pfam-B_2526 PB002526 471-510 WD40 PF00400 160-197 224-253 256-294 298-335 339-377 381-428 432-470	TBL1R_MOUSE	transducin (beta)-like 1 X-linked receptor 1	TBL1R_HUMAN	#	#	#	#	#
TDG	UDG PF03167 125-293	TDG_MOUSE	thymine-DNA glycosylase	TDG_HUMAN	DNA modification	DNA hydroxymethylation	#	G:U G:T G:hmU	C 5mC 5hmC
TDRD3	TUDOR PF00567 542-615 UBA PF00627 194-230	TDRD3_MOUSE	tudor domain containing 3	TDRD3_HUMAN	Histone modification read	#	#	H3R17me2a H4R3me2a	#
TDRD7	OST-HTH PF12872 5-73 Pfam-B_27056 PB027056 101-149 TUDOR PF00567 459-581 648-775 908-1026	TDRD7_MOUSE	tudor domain containing 7	TDRD7_HUMAN	Histone modification read	#	#	H3K9	#
TDRKH	KH_1 PF00013 54-115 126-190 Pfam-B_19308 PB019308 201-301 TUDOR PF00567 302-423	TDRKH_MOUSE	tudor and KH domain containing	TDRKH_HUMAN	RNA modification	#	#	piRNA	#
TET1	Pfam-B_12165 PB012165 2056-2134 Pfam-B_35074 PB035074 1-139 Pfam-B_6123 PB006123 782-815 Tet_JBP PF12851 1580-2052 zf-CXXC PF02008 583-624	TET1_MOUSE	tet methylcytosine dioxygenase 1	TET1_HUMAN	DNA modification	DNA hydroxymethylation	#	mC	hmC
TET2	Pfam-B_32546 PB032546 930-1046 Pfam-B_34477 PB034477 1927-1975 Tet_JBP PF12851 1290-1905	TET2_MOUSE	tet methylcytosine dioxygenase 2	TET2_HUMAN	DNA modification	DNA hydroxymethylation	#	mC	hmC
TET3	Pfam-B_188 PB000188 1613-1658 Pfam-B_19260 PB019260 1-109 Tet_JBP PF12851 850-1562	TET3_MOUSE	tet methylcytosine dioxygenase 3	TET3_HUMAN	DNA modification	DNA hydroxymethylation	#	mC	hmC
TEX10	Ipi1_N PF12333 130-235 Pfam-B_18291 PB018291 611-869	TEX10_MOUSE	testis expressed 10	TEX10_HUMAN	Histone modification write cofactor Histone modification write cofactor	Histone methylation Histone acetylation	CHD8 MLL2/3 MLL4/WBP7	#	#
TFDP1	DP PF08781 200-344 E2F_TDP PF02319 111-193	TFDP1_MOUSE	transcription factor Dp-1	TFDP1_HUMAN	Histone modification	#	RING2-L3MBTL2	#	#
TFPT	Pfam-B_10240 PB010240 10-162 Pfam-B_26015 PB026015 181-212	TFPT_MOUSE	TCF3 (E2A) fusion partner (in childhood Leukemia)	TFPT_HUMAN	Chromatin remodelling cofactor DNA modification	# DNA hydroxymethylation	Ino80	#	#
TLE1	TLE_N PF03920 1-136 WD40 PF00400 477-511 523-558 565-602 606-644 689-726 736-767	TLE1_MOUSE	transducin-like enhancer of split 1 (E(sp1) homolog Drosophila)	TLE1_HUMAN	Chromatin remodelling Histone modification cofactor	# #	#	H3	#
TLE2	TLE_N PF03920 1-132 WD40 PF00400 450-484 538-575 579-617 661-699 709-740	TLE2_MOUSE	transducin-like enhancer of split 2	TLE2_HUMAN	Histone modification cofactor	#	#	H3	H3K4 H3K9 H3K27me
TLE4	TLE_N PF03920 8-141 WD40 PF00400 480-514 526-561 568-605 609-647 692-729 739-770	TLE4_MOUSE	transducin-like enhancer of split 4	TLE4_HUMAN	Histone modification erase cofactor TF	# #	#	H3ac H4ac	#
TLK1	Pfam-B_2740 PB002740 1-109 Pfam-B_9699 PB009699 111-179 Pkinase PF00069 456-734	TLK1_MOUSE	tousled-like kinase 1	TLK1_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10	H3S10ph
TLK2	Pfam-B_24604 PB024604 91-129 Pfam-B_3701 PB003701 1-89 Pkinase PF00069 462-741	TLK2_MOUSE	tousled-like kinase 2	TLK2_HUMAN	Histone modification write	Histone phosphorylation	#	#	#
TNP1	TP1 PF02079 2-55	STP1_MOUSE	transition protein 1 (during histone to protamine replacement)	STP1_HUMAN	Chromatin remodelling	#	#	#	#
TNP2	TP2 PF01254 1-138	STP2_MOUSE	transition protein 2 (during histone to protamine replacement)	STP2_HUMAN	Chromatin remodelling	#	#	#	#
TONSL	Ank PF00023 528-560 561-591 597-629 LRR_6 PF13516 1097-1121 Pfam-B_27656 PB027656 642-670 Pfam-B_51992 PB051992 204-263 TPR_11 PF13414 350-422	TONSL_MOUSE	tonsoku-like DNA repair protein	TONSL_HUMAN	Chromatin remodelling	#	#	#	#
TOP2A	DNA_gyraseB PF00204 266-430 DNA_topoisoIV PF00521 713-1172 DTHCT PF08070 1435-1523 HATPase_c PF02518 77-224 Toprim PF01751 456-572	TOP2A_MOUSE	topoisomerase (DNA) II alpha 170kDa	TOP2A_HUMAN	Chromatin remodelling	#	#	DNA	#
TOP2B	DNA_gyraseB PF00204 287-450 DNA_topoisoIV PF00521 734-1190 DTHCT PF08070 1508-1611 HATPase_c PF02518 98-245 Toprim PF01751 477-593	TOP2B_MOUSE	topoisomerase (DNA) II beta 180kDa	TOP2B_HUMAN	Chromatin remodelling	#	WINAC	#	#
TP53	P53 PF00870 95-289 P53_TAD PF08563 5-29 P53_tetramer PF07710 318-359	P53_MOUSE	tumor protein p53	P53_HUMAN	Histone modification write cofactor TF TF	Histone acetylation TF activator TF repressor	#	H3	#
TP53BP1	53-BP1_Tudor PF09038 1483-1604 Pfam-B_14288 PB014288 1213-1356 Pfam-B_21507 PB021507 1-59 Pfam-B_24656 PB024656 1358-1386 Pfam-B_24892 PB024892 970-1000 Pfam-B_44 PB000044 528-565 Pfam-B_689 PB000689 567-698 Pfam-B_9132 PB009132 902-939 Pfam-B_9249 PB009249 1611-1967	TP53B_MOUSE	tumor protein p53 binding protein 1	TP53B_HUMAN	Histone modification read	#	#	H4K79me2 H4K20me2	#
TRIM16	PRY PF13765 375-424 Pfam-B_10855 PB010855 281-339 SPRY PF00622 426-551 zf-B_box PF00643 126-165	TRI16_MOUSE	tripartite motif containing 16	TRI16_HUMAN	Histone modification write	Histone acetylation	#	#	#
TRIM24	Bromodomain PF00439 908-992 PHD PF00628 828-873 Pfam-B_14213 PB014213 595-656 Pfam-B_4946 PB004946 372-591 zf-B_box PF00643 158-205 218-259	TIF1A_MOUSE	tripartite motif containing 24	TIF1A_HUMAN	Histone modification read	#	#	H3K4 H3K23ac	#
TRIM27	PRY PF13765 318-366 SPRY PF00622 368-493 zf-B_box PF00643 91-132 zf-C3HC4 PF00097 16-56	TRI27_MOUSE	tripartite motif containing 27	TRI27_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
TRIM28	PHD PF00628 627-672 zf-B_box PF00643 148-195 204-245 zf-RING_5 PF14634 64-122	TIF1B_MOUSE	tripartite motif containing 28	TIF1B_HUMAN	Histone modification read	#	#	H3	#
TRIM33	Bromodomain PF00439 966-1051 PHD PF00628 889-933 Pfam-B_10963 PB010963 664-696 Pfam-B_11449 PB011449 608-663 Pfam-B_11628 PB011628 535-606 zf-B_box PF00643 212-258 271-312 zf-RING_2 PF13639 123-185	TRI33_MOUSE	tripartite motif containing 33	TRI33_HUMAN	Histone modification read	#	#	H3K9me3 H3K18ac	#
TRRAP	FAT PF02259 2849-3204 PI3_PI4_kinase PF00454 3526-3783 Pfam-B_11387 PB011387 1471-1587 Pfam-B_12811 PB012811 141-238 Pfam-B_15427 PB015427 1-139 Pfam-B_3253 PB003253 1858-1890 1946-2001 Pfam-B_6491 PB006491 1589-1667 Pfam-B_6680 PB006680 2445-2544	TRRAP_MOUSE	transformation/transcription domain-associated protein	TRRAP_HUMAN	Histone modification write cofactor	Histone acetylation	SWR PCAF TFTC-HAT NuA4 SAGA NuA4-related complex STAGA	#	#
TSSK6	Pkinase PF00069 12-267	TSSK6_MOUSE	testis-specific serine kinase 6	TSSK6_HUMAN	Histone modification write	Histone phosphorylation	#	H1 H2A H2AX H3	#
TTK	Pfam-B_2743 PB002743 1-291 Pkinase PF00069 525-791	TTK_MOUSE	TTK protein kinase	TTK_HUMAN	Histone modification write cofactor	Histone phosphorylation	#	H2AT120	H2AT120ph
TYW5	Cupin_8 PF13621 16-256	TYW5_MOUSE	tRNA-yW synthesizing protein 5	TYW5_HUMAN	RNA modification	#	#	#	#
UBE2A	UQ_con PF00179 8-145	UBE2A_MOUSE	ubiquitin-conjugating enzyme E2A	UBE2A_HUMAN	Histone modification write	Histone ubiquitination	#	H2A H2BK120	H2BK120ub1
UBE2B	UQ_con PF00179 8-145	UBE2B_MOUSE	ubiquitin-conjugating enzyme E2B	UBE2B_HUMAN	Histone modification write	Histone ubiquitination	#	H2A H2BK121	H2BK120ub2
UBE2D1	UQ_con PF00179 5-142	UB2D1_MOUSE	ubiquitin-conjugating enzyme E2D 1	UB2D1_HUMAN	Histone modification write	Histone ubiquitination	#	H2BK48	H2BK48ub
UBE2D3	UQ_con PF00179 5-142	UB2D3_MOUSE	ubiquitin-conjugating enzyme E2D 3	UB2D3_HUMAN	Histone modification write	Histone ubiquitination	#	H2AK119	H2AK119ub
UBE2E1	UQ_con PF00179 51-188	UB2E1_MOUSE	ubiquitin-conjugating enzyme E2E 1	UB2E1_HUMAN	Histone modification write	Histone ubiquitination	#	H2BK120	H2BK120ub
UBE2H	UQ_con PF00179 9-145	UBE2H_MOUSE	ubiquitin-conjugating enzyme E2H	UBE2H_HUMAN	Histone modification write	Histone ubiquitination	#	H2A H2B	H2Aub H2Bub
UBE2N	UQ_con PF00179 7-144	UBE2N_MOUSE	ubiquitin-conjugating enzyme E2N	UBE2N_HUMAN	Histone modification write	Histone ubiquitination	#	H2AX	H2AXub
UBE2T	UQ_con PF00179 6-147	UBE2T_MOUSE	ubiquitin-conjugating enzyme E2T (putative)	UBE2T_HUMAN	Histone modification write	Histone ubiquitination	#	#	#
UBN1	HUN PF08729 115-169 UBN_AB PF14075 353-575	UBN1_MOUSE	ubinuclein 1	UBN1_HUMAN	Histone modification write cofactor	Histone methylation	#	#	#
UBR2	ClpS PF02617 221-302 Pfam-B_10464 PB010464 668-730 Pfam-B_14814 PB014814 1413-1491 Pfam-B_15951 PB015951 1298-1365 Pfam-B_2665 PB002665 1020-1065 zf-UBR PF02207 97-167	UBR2_MOUSE	ubiquitin protein ligase E3 component n-recognin 2	UBR2_HUMAN	Histone modification write	Histone ubiquitination	#	H2A	#
UBR5	E3_UbLigase_EDD PF11547 178-230 HECT PF00632 2497-2799 PABP PF00658 2376-2449 Pfam-B_10556 PB010556 1381-1499 Pfam-B_14783 PB014783 601-649 Pfam-B_18259 PB018259 22-174 Pfam-B_5733 PB005733 1011-1149 Pfam-B_664 PB000664 651-1009 Pfam-B_8293 PB008293 1591-1748 Pfam-B_8878 PB008878 1249-1379 zf-UBR PF02207 1177-1248	UBR5_MOUSE	ubiquitin protein ligase E3 component n-recognin 5	UBR5_HUMAN	Chromatin remodelling Histone modification write cofactor	# Histone ubiquitination	#	H2A H2AX	H2Aub H2AXub
UBR7	Pfam-B_38998 PB038998 361-423 zf-UBR PF02207 44-115	UBR7_MOUSE	ubiquitin protein ligase E3 component n-recognin 7 (putative)	UBR7_HUMAN	DNA modification cofactor	DNA methylation	#	#	#
UCHL5	Peptidase_C12 PF01088 7-211	UCHL5_MOUSE	ubiquitin carboxyl-terminal hydrolase L5	UCHL5_HUMAN	Histone modification erase cofactor	Histone ubiquitination	Ino80	#	#
UHRF1	DUF3590 PF12148 140-236 PHD PF00628 317-366 SAD_SRA PF02182 415-586 ubiquitin PF00240 6-76	UHRF1_MOUSE	ubiquitin-like with PHD and ring finger domains 1	UHRF1_HUMAN	Histone modification read Histone modification write cofactor	Histone ubiquitination #	#	H3K9me3 H3R2 H3 mCG	H3ub
UHRF2	DUF3590 PF12148 177-261 PHD PF00628 346-395 SAD_SRA PF02182 444-616 ubiquitin PF00240 6-76	UHRF2_MOUSE	ubiquitin-like with PHD and ring finger domains 2 E3 ubiquitin protein ligase	UHRF2_HUMAN	Histone modification read	#	#	H3K9me3 mCG	#
UIMC1	Pfam-B_20901 PB020901 471-524	UIMC1_MOUSE	ubiquitin interaction motif containing 1	UIMC1_HUMAN	Histone modification read	#	BRCA1-A	H2AK63ub H2AXK63ub H2BK63ub	#
USP3	UCH PF00443 158-508 zf-UBP PF02148 29-107	UBP3_MOUSE	ubiquitin specific peptidase 3	UBP3_HUMAN	Histone modification write	Histone ubiquitination	#	H2Aub H2Bub	H2A H2B
USP7	MATH PF00917 56-197 Pfam-B_12182 PB012182 591-618 Pfam-B_45828 PB045828 1-39 UCH PF00443 213-518 USP7_C2 PF14533 874-1088 USP7_ICP0_bdg PF12436 619-865	UBP7_MOUSE	ubiquitin specific peptidase 7 (herpes virus-associated)	UBP7_HUMAN	Histone modification erase DNA modification cofactor	Histone ubiquitination DNA methylation	BCOR	H2Bub	H2B
USP11	DUSP PF06337 99-185 Pfam-B_176820 PB176820 1-47 UCH PF00443 308-927 Ubiquitin_3 PF14836 198-285	UBP11_MOUSE	ubiquitin specific peptidase 11	UBP11_HUMAN	Histone modification erase cofactor	Histone ubiquitination	#	#	#
USP12	UCH PF00443 38-366	UBP12_MOUSE	ubiquitin specific peptidase 12	UBP12_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Aub	H2A
USP15	DUSP PF06337 27-119 UCH PF00443 288-930 USP7_C2 PF14533 459-614 Ubiquitin_3 PF14836 135-222	UBP15_MOUSE	ubiquitin specific peptidase 15	UBP15_HUMAN	Histone modification erase	Histone ubiquitination	#	H2BK120ub	H2BK120
USP16	UCH PF00443 195-819 zf-UBP PF02148 48-128	UBP16_MOUSE	ubiquitin specific peptidase 16	UBP16_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Aub	H2A
USP17L2	HABP4_PAI-RBP1 PF04774 374-458 Pfam-B_24444 PB024444 1-39 UCH PF00443 79-372	U17PE_MOUSE	ubiquitin specific peptidase 17-like family member 2	U17L2_HUMAN	Histone modification erase cofactor	Histone ubiquitination	#	#	#
USP21	UCH PF00443 211-555	UBP21_MOUSE	ubiquitin specific peptidase 21	UBP21_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Aub	H2A
USP22	UCH PF00443 175-517 zf-UBP PF02148 63-124	UBP22_MOUSE	ubiquitin specific peptidase 22	UBP22_HUMAN	Histone modification write cofactor	Histone ubiquitination	SAGA	H2Aub H2Bub	H2A H2B
USP36	Pfam-B_17191 PB017191 1088-1118 Pfam-B_20267 PB020267 1065-1087 UCH PF00443 121-420	UBP36_MOUSE	ubiquitin specific peptidase 36	UBP36_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	H2Bub	H2B
USP44	UCH PF00443 272-675 zf-UBP PF02148 29-91	UBP44_MOUSE	ubiquitin specific peptidase 44	UBP44_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Bub1	H2B
USP46	UCH PF00443 34-362	UBP46_MOUSE	ubiquitin specific peptidase 46	UBP46_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Aub	H2A
USP49	UCH PF00443 252-654 zf-UBP PF02148 20-88	UBP49_MOUSE	ubiquitin specific peptidase 49	UBP49_HUMAN	Histone modification erase	Histone ubiquitination	#	H2Bub	H2B
UTY	JmjC PF02373 1080-1188 Pfam-B_2066 PB002066 1-49 Pfam-B_604 PB000604 580-716 Pfam-B_972 PB000972 718-1056 TPR_1 PF00515 127-160 315-348 349-377 TPR_17 PF13431 269-301 TPR_8 PF13181 202-233	UTY_MOUSE	ubiquitously transcribed tetratricopeptide repeat containing Y-linked	UTY_HUMAN	Histone modification erase	Histone ubiquitination	#	H3K27me	#
VDR	Hormone_recep PF00104 209-418 zf-C4 PF00105 22-91	VDR_MOUSE	vitamin D (1 25- dihydroxyvitamin D3) receptor	VDR_HUMAN	Chromatin remodelling cofactor TF	# #	#	H2BK12ac H3K14ac H4K16ac	#
VPS72	YL1 PF05764 4-218 YL1_C PF08265 290-319	VPS72_MOUSE	vacuolar protein sorting 72 homolog (S. cerevisiae)	VPS72_HUMAN	Histone modification write cofactor	Histone acetylation	NuA4 NuA4-related complex	#	#
VRK1	Pkinase PF00069 37-325	VRK1_MOUSE	vaccinia related kinase 1	VRK1_HUMAN	Histone modification write	Histone phosphorylation	#	H3S10 H3T3	H3S10ph H3T3ph
WAC	WW PF00397 131-160	WAC_MOUSE	WW domain containing adaptor with coiled-coil	WAC_HUMAN	Histone modification write cofactor	Histone ubiquitination	#	#	#
WDR5	WD40 PF00400 36-73 77-115 119-157 161-199 203-242 246-287 291-331	WDR5_MOUSE	WD repeat domain 5	WDR5_HUMAN	Histone modification read	#	ATAC NSL RING2-L3MBTL2 COMPASS Menin-associated_HMT MLL-HCF CHD8 MLL2/3 COMPASS-like MLL1 2 MLL4/WBP7 COMPASS-like MLL3 4	H3K4 H3K4me1 H3K4me2 H3K4me3	#
WDR77	Pfam-B_26289 PB026289 1-49 WD40 PF00400 117-153 157-196 245-284	MEP50_MOUSE	WD repeat domain 77	MEP50_HUMAN	Histone modification write	Histone methylation	methylosome	H2A H4	H2Ame H4me
WDR82	WD40 PF00400 12-49 97-135 245-267 273-304	WDR82_MOUSE	WD repeat domain 82	WDR82_HUMAN	Histone modification write cofactor	Histone methylation	COMPASS	#	#
WHSC1	HMG_box PF00505 455-508 PHD PF00628 833-875 PWWP PF00855 220-332 878-968 SET PF00856 1074-1180	NSD2_MOUSE	Wolf-Hirschhorn syndrome candidate 1	NSD2_HUMAN	Histone modification write	Histone methylation	#	H3K27	H3K27me
WHSC1L1	PWWP PF00855 268-378 958-1047 Pfam-B_7848 PB007848 619-671 SET PF00856 1156-1262	NSD3_MOUSE	Wolf-Hirschhorn syndrome candidate 1-like 1	NSD3_HUMAN	Chromatin remodelling cofactor TF	# #	#	H3K4 H3K27	#
WSB2	Pfam-B_17306 PB017306 1-52 SOCS_box PF07525 366-402 WD40 PF00400 83-139 143-182 187-225 229-267 288-321 337-361	WSB2_MOUSE	WD repeat and SOCS box containing 2	WSB2_HUMAN	Histone modification write	Histone ubiquitination	#	#	#
YAF2	zf-RanBP PF00641 20-46	YAF2_MOUSE	YY1 associated factor 2	YAF2_HUMAN	Chromatin remodelling cofactor	#	BCOR RING2-L3MBTL2 RING2-FBRS	#	#
YEATS2	Pfam-B_10841 PB010841 976-1072 Pfam-B_13347 PB013347 678-756 Pfam-B_19332 PB019332 758-854 YEATS PF03366 231-314	YETS2_MOUSE	YEATS domain containing 2	YETS2_HUMAN	Histone chaperone	#	ATAC	#	#
YEATS4	YEATS PF03366 44-126	YETS4_MOUSE	YEATS domain containing 4	YETS4_HUMAN	Histone modification write cofactor	Histone acetylation	NuA4 NuA4-related complex SRCAP	#	#
YWHAB	14-3-3 PF00244 5-238	1433B_MOUSE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta	1433B_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
YWHAE	14-3-3 PF00244 4-239	1433E_MOUSE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon	1433E_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
YWHAZ	14-3-3 PF00244 3-236	1433Z_MOUSE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	1433Z_HUMAN	Histone modification read	#	#	H3	#
YY1	zf-C2H2 PF00096 383-407 zf-H2C2_2 PF13465 339-365	TYY1_MOUSE	YY1 transcription factor	TYY1_HUMAN	Chromatin remodelling cofactor TF	# TF repressor	Ino80	DNA motif	#
ZBTB7C	BTB PF00651 24-130 zf-H2C2_2 PF13465 379-403 406-431 434-459	ZBT7C_MOUSE	zinc finger and BTB domain containing 7C	ZBT7C_HUMAN	Histone modification cofactor	#	#	#	#
ZBTB16	BTB PF00651 24-126 zf-C2H2 PF00096 491-512 630-652 zf-C2H2_4 PF13894 432-455 zf-C2H2_6 PF13912 460-486 zf-H2C2_2 PF13465 532-556 560-584 588-612	#	zinc finger and BTB domain containing 16	ZBT16_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZBTB33	BTB PF00651 22-118 zf-H2C2_2 PF13465 508-532 537-561	KAISO_MOUSE	zinc finger and BTB domain containing 33	KAISO_HUMAN	Histone modification write cofactor Histone modification erase cofactor TF	Histone acetylation Histone methylation TF repressor	#	CG mCG DNA motif	#
ZCWPW1	PWWP PF00855 315-411 Pfam-B_36867 PB036867 512-557 zf-CW PF07496 254-303	ZCPW1_MOUSE	zinc finger CW type with PWWP domain 1	ZCPW1_HUMAN	Histone modification read	#	#	H3K4me	#
ZFP57	KRAB PF01352 16-56 zf-C2H2 PF00096 91-113 175-197 zf-C2H2_4 PF13894 300-323 329-351 356-377 zf-H2C2_2 PF13465 133-156	ZFP57_MOUSE	ZFP57 zinc finger protein	ZFP57_HUMAN	TF	TF repressor	#	mC DNA motif	#
ZGPAT	G-patch PF01585 333-376	ZGPAT_MOUSE	zinc finger CCCH-type with G patch domain	ZGPAT_HUMAN	TF	TF repressor	#	DNA motif	#
ZHX1	Homeobox PF00046 297-339 467-521 573-623 665-717 Homez PF11569 776-827 Pfam-B_22595 PB022595 1-37	ZHX1_MOUSE	zinc fingers and homeoboxes 1	ZHX1_HUMAN	Chromatin remodelling Histone modification write cofactor Histone modification write cofactor	# Histone acetylation Histone methylation	#	#	#
ZMYM2	DUF3504 PF12012 1190-1361 Pfam-B_10252 PB010252 941-1179 Pfam-B_2297 PB002297 1-159 zf-FCS PF06467 323-363 365-409 417-456 459-502 528-570 576-616 631-671 719-758 760-799	ZMYM2_MOUSE	zinc finger MYM-type 2	ZMYM2_HUMAN	Histone modification erase cofactor TF	Histone acetylation #	BHC LSD-CoREST	DNA motif	#
ZMYM3	DUF3504 PF12012 1183-1354 Pfam-B_2297 PB002297 1-189 Pfam-B_24258 PB024258 191-229 Pfam-B_5192 PB005192 1100-1142 zf-FCS PF06467 304-343 345-389 402-440 443-488 490-532 538-578 583-623 626-664 671-710 712-751	ZMYM3_MOUSE	zinc finger MYM-type 3	ZMYM3_HUMAN	Histone modification erase cofactor	Histone acetylation	BHC	#	#
ZMYND8	Bromodomain PF00439 157-240 DUF3544 PF12064 412-622 PHD PF00628 90-133 PWWP PF00855 275-349 zf-MYND PF01753 1028-1062	#	zinc finger MYND-type containing 8	PKCB1_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZMYND11	Bromodomain PF00439 122-203 PWWP PF00855 238-313 Pfam-B_7883 PB007883 342-530 Pfam-B_8532 PB008532 532-560	ZMY11_MOUSE	zinc finger MYND-type containing 11	ZMY11_HUMAN	Histone modification read	Histone methylation	#	H3.3K36me3	#
ZNF217	Pfam-B_30131 PB030131 913-979 zf-C2H2 PF00096 128-150 156-178 zf-C2H2_4 PF13894 65-88 216-239 375-398 zf-H2C2_2 PF13465 485-510	#	zinc finger protein 217	ZN217_HUMAN	Histone modification erase cofactor TF	Histone acetylation TF repressor	BHC LSD-CoREST	#	#
ZNF516	zf-C2H2 PF00096 248-270 276-298 1098-1120 zf-C2H2_4 PF13894 174-197 zf-H2C2_2 PF13465 48-73	ZN516_MOUSE	zinc finger protein 516	ZN516_HUMAN	Histone modification erase cofactor TF	Histone acetylation TF repressor	LSD-CoREST	#	#
ZNF532	Pfam-B_17557 PB017557 601-719 Pfam-B_19362 PB019362 831-959 zf-C2H2 PF00096 1265-1286	ZN532_MOUSE	zinc finger protein 532	ZN532_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZNF541	ELM2 PF01448 1074-1131 Pfam-B_17081 PB017081 567-665 Pfam-B_27795 PB027795 956-1034 Pfam-B_3685 PB003685 772-954 Pfam-B_40457 PB040457 1171-1225 zf-C2H2 PF00096 168-190 zf-C2H2_4 PF13894 140-163 196-221	ZN541_MOUSE	zinc finger protein 541	ZN541_HUMAN	Chromatin remodelling	#	#	#	#
ZNF592	Pfam-B_21220 PB021220 499-547 Pfam-B_27046 PB027046 771-913 Pfam-B_379 PB000379 1-97 zf-C2H2 PF00096 1013-1036 1043-1069	ZN592_MOUSE	zinc finger protein 592	ZN592_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZNF687	zf-C2H2 PF00096 1200-1222 zf-C2H2_4 PF13894 858-881 963-986 993-1016	ZN687_MOUSE	zinc finger protein 687	ZN687_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZNF711	Pfam-B_16491 PB016491 1-63 Zfx_Zfy_act PF04704 64-368 zf-C2H2 PF00096 383-405 zf-C2H2_4 PF13894 562-583 733-756 zf-H2C2_2 PF13465 490-516 519-543 604-630 690-715 zf-H2C2_5 PF13909 414-437 647-671	ZN711_MOUSE	zinc finger protein 711	ZN711_HUMAN	Histone modification erase cofactor	Histone acetylation	#	#	#
ZNHIT1	zf-HIT PF04438 113-142	ZNHI1_MOUSE	zinc finger HIT-type containing 1	ZNHI1_HUMAN	Chromatin remodelling cofactor Histone modification erase cofactor	# Histone acetylation	SRCAP	#	#
ZRANB3	HNH PF01844 1009-1051 Helicase_C PF00271 357-435 Pfam-B_14328 PB014328 729-854 SNF2_N PF00176 40-326 zf-RanBP PF00641 621-650	ZRAB3_MOUSE	zinc finger RAN-binding domain containing 3	ZRAB3_HUMAN	Chromatin remodelling Histone modification read cofactor	# Histone methylation	#	#	#
ZZZ3	Myb_DNA-binding PF00249 652-703 Pfam-B_19065 PB019065 361-439 Pfam-B_22505 PB022505 211-359 ZZ PF00569 817-865	ZZZ3_MOUSE	zinc finger ZZ-type containing 3	ZZZ3_HUMAN	Histone modification read	#	ATAC	#	#